In:
PLOS ONE, Public Library of Science (PLoS), Vol. 15, No. 12 ( 2020-12-31), p. e0244824-
Abstract:
SARS-CoV-2 causes substantial morbidity and mortality in elderly and immunocompromised individuals, particularly in retirement homes, where transmission from asymptomatic staff and visitors may introduce the infection. Here we present a cheap and fast screening method based on direct RT-qPCR to detect SARS-CoV-2 in single or pooled gargle lavages (“mouthwashes”). This method detects individuals with large viral loads (Ct≤29) and we use it to test all staff at a nursing home daily over a period of three weeks in order to reduce the risk that the infection penetrates the facility. This or similar approaches can be implemented to protect hospitals, nursing homes and other institutions in this and future viral epidemics.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0244824
DOI:
10.1371/journal.pone.0244824.g001
DOI:
10.1371/journal.pone.0244824.g002
DOI:
10.1371/journal.pone.0244824.g003
DOI:
10.1371/journal.pone.0244824.g004
DOI:
10.1371/journal.pone.0244824.g005
DOI:
10.1371/journal.pone.0244824.s001
DOI:
10.1371/journal.pone.0244824.s002
DOI:
10.1371/journal.pone.0244824.s003
DOI:
10.1371/journal.pone.0244824.s004
DOI:
10.1371/journal.pone.0244824.r001
DOI:
10.1371/journal.pone.0244824.r002
DOI:
10.1371/journal.pone.0244824.r003
DOI:
10.1371/journal.pone.0244824.r004
DOI:
10.1371/journal.pone.0244824.r005
DOI:
10.1371/journal.pone.0244824.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2020
detail.hit.zdb_id:
2267670-3
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