In:
Circulation: Cardiovascular Quality and Outcomes, Ovid Technologies (Wolters Kluwer Health), Vol. 4, No. suppl_1 ( 2011-11)
Abstract:
Background: Syncope results in emergency department (ED) visits and hospital admissions. African-American (AA) patients often have multiple co-morbidities that translate to poorer outcome. We thought to evaluate the effect of AA race on outcome in patients with unexplained syncope. Methods: We evaluated 902 consecutive patients with unexplained pre-syncope/syncope between September 2007 and January 2009; all patients were enrolled in a prospective institutional registry. The primary endpoint was a composite of readmission for syncope, myocardial infarction (MI), stroke or death. In this study, we compared the outcome of AA to non African-American patients (non-AA). Results: There were 252 (28%) AA patients and 650 (72%) non-AA patients. When compared to non-AA patients, AA patients were older (64 ± 20 years vs. 59 ± 23 years, p 〈 0.001) and likely to have hypertension (69% vs. 47%, p 〈 0.001), diabetes (27% vs. 15%, p 〈 0.001), heart failure (12% vs. 5%, p 〈 0.001), and coronary disease (18% vs. 14%, p=0.01). During a follow-up period of 303 ± 140 days, the composite endpoint was observed in 92 (10.2%) patients and included 13 (1.4%) deaths, 5 (0.7%) strokes, 29 (3.2%) MIs and 45 (5%) syncope readmission. Multivariate regression analysis showed history of CAD (OR=1.9 95%CI 1.11-3.12), hypertension (OR=1.8 95%CI 1.03-3.43), diabetes (OR=1.7 95%CI 1.02-2.78) and AA race (OR=2.1 95%CI 1.30-3.28) to be predictors of worse outcome. Conclusions: African-American patients presenting with unexplained syncope have significantly worse 1-year outcome than non-AA. This is likely due in part to a higher incidence of significant co-morbidities in AA patients.
Type of Medium:
Online Resource
ISSN:
1941-7713
,
1941-7705
DOI:
10.1161/circoutcomes.4.suppl_1.AP122
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2011
detail.hit.zdb_id:
2453882-6
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