In:
International Journal of Dermatology, Wiley, Vol. 52, No. 9 ( 2013-09), p. 1135-1139
Abstract:
Livedoid vasculopathy ( LV ) is a thrombotic vasculopathy of the skin of unknown origin. No treatment has been validated in this indication, but case reports suggest the successful use of intravenous immunoglobulins (IVIG) in LV . Methods Outcomes in five patients treated with IVIG for treatment‐resistant ulcerated LV were retrospectively analyzed. Results Treatment with IVIG induced complete remission (based on clinical evaluation and a pain‐related visual analog scale) in four patients but was ineffective in one patient. Three patients relapsed; the median time to relapse was 10.7 months. Re‐treatment with IVIG in these three patients was successful. Conclusions These cases confirm previous reports that IVIG seems to be a rapid, effective, and safe treatment for patients with idiopathic refractory ulcerated LV . However, a placebo‐controlled study is mandatory to confirm these results.
Type of Medium:
Online Resource
ISSN:
0011-9059
,
1365-4632
DOI:
10.1111/ijd.2013.52.issue-9
DOI:
10.1111/j.1365-4632.2012.05826.x
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
2020365-2
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