In:
European Journal of Neurology, Wiley, Vol. 28, No. 4 ( 2021-04), p. 1292-1298
Abstract:
Previous studies reported reduced decision‐making abilities for patients with multiple sclerosis (MS) relative to healthy controls (HC). This study aimed to evaluate whether these problems arise when sampling information or when pondering about the evidence collected. Methods In a cross‐sectional, controlled study, 43 relapsing‐remitting MS patients (RRMS; Expanded Disability Status Scale 1.5, range 0–4) and 53 HC performed an information sampling task (‘beads task’), a health‐related framing task, and neuropsychological background tests. Results In the beads task, patients collected as much information as HC prior to a decision. However, there were twice as many patients as HC making irrational decisions, that is, decisions against the evidence collected (RRMS: 26/43, 60%; HC: 16/53, 30%; p = 0.003). Compared to HC, patients also showed a stronger framing effect, that is, they were more strongly biased by the way health‐related information was presented ( p 〈 0.05, Cohen's d = 0.5). Overall, the framing effect predicted whether a participant would make irrational decisions (OR 2.12, 95% CI 1.29–3.49, p 〈 0.001). Conclusions Predecisional information sampling is intact in RRMS. However, compared to HC, patients are more likely to make irrational decisions and to be biased by the way health‐related information is framed. This warrants caution in communication, especially in the medical context, with patients.
Type of Medium:
Online Resource
ISSN:
1351-5101
,
1468-1331
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2020241-6
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