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Use of comparative effectiveness research for similar Chinese patent medicine for angina pectoris of coronary heart disease: a new approach based on patient-important outcomes

Cao, Hongbo ; Zhai, Jingbo ; Mu, Wei ; [et al.]

Springer Science and Business Media LLC ; 2014

In: Trials Vol. 15, No. 1 ( 2014-12)

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In: Trials, Springer Science and Business Media LLC, Vol. 15, No. 1 ( 2014-12)

Type of Medium: Online Resource

ISSN: 1745-6215

URL: Article

DOI: 10.1186/1745-6215-15-84

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2014

detail.hit.zdb_id: 2040523-6

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Analysis of Spatiotemporal Characteristics of Pandemic SARS Spread in Mainland China

Cao, Chunxiang ; Chen, Wei ; Zheng, Sheng ; [et al.]

Hindawi Limited ; 2016

In: BioMed Research International Vol. 2016 ( 2016), p. 1-12

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In: BioMed Research International, Hindawi Limited, Vol. 2016 ( 2016), p. 1-12

Abstract: Severe acute respiratory syndrome (SARS) is one of the most severe emerging infectious diseases of the 21st century so far. SARS caused a pandemic that spread throughout mainland China for 7 months, infecting 5318 persons in 194 administrative regions. Using detailed mainland China epidemiological data, we study spatiotemporal aspects of this person-to-person contagious disease and simulate its spatiotemporal transmission dynamics via the Bayesian Maximum Entropy (BME) method. The BME reveals that SARS outbreaks show autocorrelation within certain spatial and temporal distances. We use BME to fit a theoretical covariance model that has a sine hole spatial component and exponential temporal component and obtain the weights of geographical and temporal autocorrelation factors. Using the covariance model, SARS dynamics were estimated and simulated under the most probable conditions. Our study suggests that SARS transmission varies in its epidemiological characteristics and SARS outbreak distributions exhibit palpable clusters on both spatial and temporal scales. In addition, the BME modelling demonstrates that SARS transmission features are affected by spatial heterogeneity, so we analyze potential causes. This may benefit epidemiological control of pandemic infectious diseases.

Type of Medium: Online Resource

ISSN: 2314-6133 , 2314-6141

URL: Article

DOI: 10.1155/2016/7247983

Language: English

Publisher: Hindawi Limited

Publication Date: 2016

detail.hit.zdb_id: 2698540-8

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Heterogeneous bimetallic sulfides based seawater electrolysis towards stable industrial-level large current density

Wang, Chengzhong ; Zhu, Mingze ; Cao, Zhengyi ; [et al.]

Elsevier BV ; 2021

In: Applied Catalysis B: Environmental Vol. 291 ( 2021-08), p. 120071-

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In: Applied Catalysis B: Environmental, Elsevier BV, Vol. 291 ( 2021-08), p. 120071-

Type of Medium: Online Resource

ISSN: 0926-3373

URL: Article

DOI: 10.1016/j.apcatb.2021.120071

Language: English

Publisher: Elsevier BV

Publication Date: 2021

detail.hit.zdb_id: 2017331-3

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Observed evidence of the growing contributions to aerosol pollution of wildfires with diverse spatiotemporal distinctions in China

Chen, Yiyu ; Cao, Chunxiang ; Cao, Yunfeng ; [et al.]

Elsevier BV ; 2021

In: Journal of Cleaner Production Vol. 298 ( 2021-05), p. 126860-

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In: Journal of Cleaner Production, Elsevier BV, Vol. 298 ( 2021-05), p. 126860-

Type of Medium: Online Resource

ISSN: 0959-6526

URL: Article

DOI: 10.1016/j.jclepro.2021.126860

Language: English

Publisher: Elsevier BV

Publication Date: 2021

detail.hit.zdb_id: 1179393-4

detail.hit.zdb_id: 2029338-0

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An investigation of metal ion diffusion in ceria‐based solid oxide fuel cell with barium‐containing anode

Cao, Jiafeng ; Ji, Yuexia ; Zhou, Xuejun ; [et al.]

Wiley ; 2018

In: Journal of the American Ceramic Society Vol. 101, No. 12 ( 2018-12), p. 5791-5800

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In: Journal of the American Ceramic Society, Wiley, Vol. 101, No. 12 ( 2018-12), p. 5791-5800

Abstract: Metal ion diffusion is an effective strategy to suppress the internal electronic short circuit in ceria‐based solid oxide fuel cells ( SOFC s). This could be achieved by fabricating an electron‐blocking layer between the barium‐containing anode and ceria‐based electrolyte. In this paper, a 0.6NiO‐0.4BaZr 0.1 Ce 0.7 Y 0.2 O 3‐δ (NiO‐ BZCY ) anode‐supported cell based on Gd 0.1 Ce 0.9 O 2‐δ ( GDC ) electrolyte was employed to evaluate the internal metal ion diffusion behavior. The high open circuit voltages of about 1 V obtained at 550‐700°C can be attributed to in situ formation of an electron‐blocking interlayer between NiO‐ BZCY and GDC . Microstructural analyses of the interlayer grains obtained by traditional solid‐state reaction were carried out. Phase identification demonstrated that the electron‐blocking interlayer had a perovskite structure. SEM and TEM analyses indicated formation of a new compound in the interlayer, of which the composition was determined as Zr, Y, and Ni co‐doped BaCe 0.9 Gd 0.1 O 3 with orthorhombic structure.

Type of Medium: Online Resource

ISSN: 0002-7820 , 1551-2916

URL: Issue

URL: Article

DOI: 10.1111/jace.2018.101.issue-12

DOI: 10.1111/jace.15796

RVK:

VA 1120

Language: English

Publisher: Wiley

Publication Date: 2018

detail.hit.zdb_id: 2008170-4

detail.hit.zdb_id: 219232-9

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Table_2.xlsx

Cao, Chunxiang ; Wu, Ran ; Wang, Shubei ; [et al.]

Frontiers Media SA ; 2024

In: Frontiers in Immunology Vol. 15 ( 2024-3-27)

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In: Frontiers in Immunology, Frontiers Media SA, Vol. 15 ( 2024-3-27)

Abstract: A mouse model of irradiation (IR)-induced heart injury was established to investigate the early changes in cardiac function after radiation and the role of cardiac macrophages in this process. Methods Cardiac function was evaluated by heart-to-tibia ratio, lung-to-heart ratio and echocardiography. Immunofluorescence staining and flow cytometry analysis were used to evaluate the changes of macrophages in the heart. Immune cells from heart tissues were sorted by magnetic beads for single-cell RNA sequencing, and the subsets of macrophages were identified and analyzed. Trajectory analysis was used to explore the differentiation relationship of each macrophage subset. The differentially expressed genes (DEGs) were compared, and the related enriched pathways were identified. Single-cell regulatory network inference and clustering (SCENIC) analysis was performed to identify the potential transcription factors (TFs) which participated in this process. Results Cardiac function temporarily decreased on Day 7 and returned to normal level on Day 35, accompanied by macrophages decreased and increased respectively. Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a high C5ar1 high ) on Day 7 and interferon-associated macrophage (Ccr2 high Isg15 high ) on Day 35. Moreover, we observed cardiac macrophages polarized over these two-time points based on M1/M2 and CCR2/major histocompatibility complex II (MHCII) expression. Finally, Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analyses suggested that macrophages on Day 7 were characterized by an inflammatory senescent phenotype with enhanced chemotaxis and inflammatory factors, while macrophages on Day 35 showed enhanced phagocytosis with reduced inflammation, which was associated with interferon-related pathways. SCENIC analysis showed AP-1 family members were associated with IR-induced macrophages changes. Conclusion We are the first study to characterize the diversity, features, and evolution of macrophages during the early stages in an IR-induced cardiac injury animal model.

Type of Medium: Online Resource

ISSN: 1664-3224

URL: Article

DOI: 10.3389/fimmu.2024.1363278

DOI: 10.3389/fimmu.2024.1363278.s001

DOI: 10.3389/fimmu.2024.1363278.s002

DOI: 10.3389/fimmu.2024.1363278.s003

DOI: 10.3389/fimmu.2024.1363278.s004

DOI: 10.3389/fimmu.2024.1363278.s005

DOI: 10.3389/fimmu.2024.1363278.s006

DOI: 10.3389/fimmu.2024.1363278.s007

DOI: 10.3389/fimmu.2024.1363278.s008

DOI: 10.3389/fimmu.2024.1363278.s009

DOI: 10.3389/fimmu.2024.1363278.s010

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2024

detail.hit.zdb_id: 2606827-8

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Comparing Regional Distribution Equity among Doctors in China before and after the 2009 Medical Reform Policy: A Data Analysis from 2002 to 2017

Cao, Xiaolin ; Bai, Ge ; Cao, Chunxiang ; [et al.]

MDPI AG ; 2020

In: International Journal of Environmental Research and Public Health Vol. 17, No. 5 ( 2020-02-27), p. 1520-

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In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 5 ( 2020-02-27), p. 1520-

Abstract: Background: Although China began implementing medical reforms in 2009 aimed at fair allocation of the regional distribution of doctors, little is known of their impact. This study analyzed the geographic distribution of doctors from 2002 to 2017. Methods: This study calculated the Gini coefficient and Theil index among doctors in the eastern, central, and western regions (Category 1) of China, and in urban and rural areas (Category 2). The statistical significance of fairness changes was analyzed using the Mann–Whitney U test. Results: The annual growth rates of the number of doctors for the periods from 2002 to 2009 and 2010 to 2017 were 2.38% and 4.44%. The Gini coefficients among Category 1 were lower than those in Category 2, and statistically decreased after the medical reforms (P 〈 0.01) but continued to increase in Category 2 (P = 0.463). In 2017, the Theil decomposition result of Category 1 was 74.33% for the between-group, and in Category 2, it was 95.22% for the within-group. Conclusions: The fairness among the regional distribution of doctors in Category 1 is now at a high level and is better than that before the reforms. While the fairness in Category 2 is worse than that before the reforms, it causes moderate inequality and is continually decreasing. Overall unfairness was found to be derived from the between-group.

Type of Medium: Online Resource

ISSN: 1660-4601

URL: Article

DOI: 10.3390/ijerph17051520

Language: English

Publisher: MDPI AG

Publication Date: 2020

detail.hit.zdb_id: 2175195-X

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Risk analysis for the highly pathogenic avian influenza in Mainland China using meta-modeling

Cao, ChunXiang ; Xu, Min ; Chang, ChaoYi ; [et al.]

Springer Science and Business Media LLC ; 2010

In: Chinese Science Bulletin Vol. 55, No. 36 ( 2010-12), p. 4168-4178

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In: Chinese Science Bulletin, Springer Science and Business Media LLC, Vol. 55, No. 36 ( 2010-12), p. 4168-4178

Type of Medium: Online Resource

ISSN: 1001-6538 , 1861-9541

URL: Article

DOI: 10.1007/s11434-010-4225-x

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2010

detail.hit.zdb_id: 2069521-4

detail.hit.zdb_id: 2816140-3

SSG: 11

SSG: 6,25

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The novel H1N1 Influenza A global airline transmission and early warning without travel containments

Chang, ChaoYi ; Cao, ChunXiang ; Wang, Qiao ; [et al.]

Springer Science and Business Media LLC ; 2010

In: Chinese Science Bulletin Vol. 55, No. 26 ( 2010-9), p. 3030-3036

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In: Chinese Science Bulletin, Springer Science and Business Media LLC, Vol. 55, No. 26 ( 2010-9), p. 3030-3036

Type of Medium: Online Resource

ISSN: 1001-6538 , 1861-9541

URL: Article

DOI: 10.1007/s11434-010-3180-x

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2010

detail.hit.zdb_id: 2069521-4

detail.hit.zdb_id: 2816140-3

SSG: 11

SSG: 6,25

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ALMA $[{\rm{N}}\,{\rm{II}}]$ 205 μ m Imaging Spectroscopy of the Lensed Submillimeter Galaxy ID 141 at Redshift 4.24

Cheng, Cheng ; Cao, Xiaoyue ; Lu, Nanyao ; [et al.]

American Astronomical Society ; 2020

In: The Astrophysical Journal Vol. 898, No. 1 ( 2020-07-20), p. 33-

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In: The Astrophysical Journal, American Astronomical Society, Vol. 898, No. 1 ( 2020-07-20), p. 33-

Type of Medium: Online Resource

ISSN: 1538-4357

URL: Article

DOI: 10.3847/1538-4357/ab980b

Language: Unknown

Publisher: American Astronomical Society

Publication Date: 2020

detail.hit.zdb_id: 2207648-7

detail.hit.zdb_id: 1473835-1

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