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1

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ESICM LIVES 2016: part one : Milan, Italy. 1-5 October 2016

Bos, L. ; Schouten, L. ; van Vught, L. ; [et al.]

Springer Science and Business Media LLC ; 2016

In: Intensive Care Medicine Experimental Vol. 4, No. S1 ( 2016-09-29)

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In: Intensive Care Medicine Experimental, Springer Science and Business Media LLC, Vol. 4, No. S1 ( 2016-09-29)

Type of Medium: Online Resource

ISSN: 2197-425X

URL: Article

DOI: 10.1186/s40635-016-0098-x

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2016

detail.hit.zdb_id: 2740385-3

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2

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ESICM LIVES 2016: part three : Milan, Italy. 1–5 October 2016

Velasquez, T. ; GETGAG Working Group ; Mackey, G. ; [et al.]

Springer Science and Business Media LLC ; 2016

In: Intensive Care Medicine Experimental Vol. 4, No. S1 ( 2016-9)

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In: Intensive Care Medicine Experimental, Springer Science and Business Media LLC, Vol. 4, No. S1 ( 2016-9)

Type of Medium: Online Resource

ISSN: 2197-425X

URL: Article

DOI: 10.1186/s40635-016-0100-7

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2016

detail.hit.zdb_id: 2740385-3

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Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

Tyndall, A. J. ; Bannert, B. ; Vonk, M. ; [et al.]

BMJ ; 2010

In: Annals of the Rheumatic Diseases Vol. 69, No. 10 ( 2010-10-01), p. 1809-1815

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In: Annals of the Rheumatic Diseases, BMJ, Vol. 69, No. 10 ( 2010-10-01), p. 1809-1815

Type of Medium: Online Resource

ISSN: 0003-4967

URL: Article

DOI: 10.1136/ard.2009.114264

RVK:

XA 10000

Language: English

Publisher: BMJ

Publication Date: 2010

detail.hit.zdb_id: 1481557-6

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Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

COVIDSurg Collaborative ; Dajti, I ; Valenzuela, J I ; [et al.]

Oxford University Press (OUP) ; 2021

In: British Journal of Surgery Vol. 108, No. 11 ( 2021-11-11), p. 1274-1292

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In: British Journal of Surgery, Oxford University Press (OUP), Vol. 108, No. 11 ( 2021-11-11), p. 1274-1292

Abstract: To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide range of surgical services for selected patients.

Type of Medium: Online Resource

ISSN: 0007-1323 , 1365-2168

URL: Article

DOI: 10.1093/bjs/znab183

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2021

detail.hit.zdb_id: 2006309-X

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The role of geosciences in the assessment of low-temperature geothermal resources (N-Portugal): a review

Marques, José M. ; Carreira, P. M. ; Marques, J. E. ; [et al.]

Springer Science and Business Media LLC ; 2010

In: Geosciences Journal Vol. 14, No. 4 ( 2010-12), p. 423-442

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In: Geosciences Journal, Springer Science and Business Media LLC, Vol. 14, No. 4 ( 2010-12), p. 423-442

Type of Medium: Online Resource

ISSN: 1226-4806 , 1598-7477

URL: Article

DOI: 10.1007/s12303-010-0034-0

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2010

detail.hit.zdb_id: 2140684-4

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Evidence that deletion at FCGR3B is a risk factor for systemic sclerosis

McKinney, C ; Broen, J C A ; Vonk, M C ; [et al.]

Springer Science and Business Media LLC ; 2012

In: Genes & Immunity Vol. 13, No. 6 ( 2012-09), p. 458-460

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In: Genes & Immunity, Springer Science and Business Media LLC, Vol. 13, No. 6 ( 2012-09), p. 458-460

Type of Medium: Online Resource

ISSN: 1466-4879 , 1476-5470

URL: Article

DOI: 10.1038/gene.2012.15

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2012

detail.hit.zdb_id: 2006268-0

SSG: 12

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Expression of types I, III and IV collagen genes in fibrotic skin and nerve lesions of toxic oil syndrome patients

GOMEZ-REINO, J J ; SANDBERG, M ; CARREIRA, P E ; [et al.]

Oxford University Press (OUP) ; 2008

In: Clinical and Experimental Immunology Vol. 93, No. 1 ( 2008-06-28), p. 103-107

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In: Clinical and Experimental Immunology, Oxford University Press (OUP), Vol. 93, No. 1 ( 2008-06-28), p. 103-107

Abstract: We have studied the skin and nerve fibrosis in toxic oil syndrome by in situ hybridization using specific cDNA probes for types I, III, and IV collagens, Fibroblasts with high levels of type I and III collagen mRNA were observed in biopsies from fibrotic skin areas. Similarly, type IV collagen mRNA was abundant in cells within the fibrotic process of the nerves. These results suggest that the excessive accumulation of collagen in toxic oil syndrome results from transcriptional activation of collagen genes in a subpopulation of fibroblasts.

Type of Medium: Online Resource

ISSN: 0009-9104 , 1365-2249

URL: Article

DOI: 10.1111/j.1365-2249.1993.tb06504.x

RVK:

XA 36770

RVK:

XA 10000

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2008

detail.hit.zdb_id: 2020024-9

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Systemic sclerosis without antinuclear antibodies or Raynaud's phenomenon: a multicentre study in the prospective EULAR Scleroderma Trials and Research (EUSTAR) database

Schneeberger, D. ; Tyndall, A. ; Kay, J. ; [et al.]

Oxford University Press (OUP) ; 2013

In: Rheumatology Vol. 52, No. 3 ( 2013-03-01), p. 560-567

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In: Rheumatology, Oxford University Press (OUP), Vol. 52, No. 3 ( 2013-03-01), p. 560-567

Type of Medium: Online Resource

ISSN: 1462-0324 , 1462-0332

URL: Article

DOI: 10.1093/rheumatology/kes315

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2013

detail.hit.zdb_id: 1474143-X

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9

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An open-label pilot study of infliximab therapy in diffuse cutaneous systemic sclerosis

Denton, C P ; Engelhart, M ; Tvede, N ; [et al.]

BMJ ; 2009

In: Annals of the Rheumatic Diseases Vol. 68, No. 9 ( 2009-09), p. 1433-1439

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In: Annals of the Rheumatic Diseases, BMJ, Vol. 68, No. 9 ( 2009-09), p. 1433-1439

Abstract: The safety and potential efficacy of a chimaeric anti-tumour necrosis factor alpha monoclonal antibody (infliximab) were examined in diffuse cutaneous systemic sclerosis (dcSSc). Methods: A 26-week open-label pilot study in which 16 cases of dcSSc received five infusions of infliximab (5 mg/kg). Clinical assessment included skin sclerosis score, scleroderma health assessment questionnaire, self-reported functional score and physician global visual analogue scale. Collagen turnover, skin biopsy analysis and full safety evaluation were performed. Results: There was no significant change in skin score at 26 weeks but a trend for lower modified Rodnan skin score at 22 weeks (OR 17, 95% CI 6 to 46) compared with peak value (OR 29, 95% CI 11 to 44; p = 0.10). Serum aminoterminal propeptide of type III collagen level was significantly lower at week 26 compared with baseline (p = 0.03). Secretion of type I collagen by dermal fibroblasts was reduced at 26 weeks compared with baseline (p = 0.02). There were no deaths during the study and no suspected unexpected serious adverse reactions. 21 serious adverse events (AE) occurred in seven subjects, mostly attributable to dcSSc. 127 distinct AE occurred in 16 subjects. Of these, 19 AE (15%) were probably or definitely related to infliximab treatment. Eight (50%) patients prematurely discontinued infliximab. Anti-infliximab antibodies developed during the study in five subjects and were significantly associated with suspected infusion reactions (p = 0.025). Conclusion: In dcSSc infliximab did not show clear benefit at 26 weeks but was associated with clinical stabilisation and a fall in two laboratory markers of collagen synthesis. The frequency of suspected infusion reactions may warrant additional immunosuppression in any future studies in systemic sclerosis.

Type of Medium: Online Resource

ISSN: 0003-4967 , 1468-2060

URL: Article

DOI: 10.1136/ard.2008.096123

RVK:

XA 10000

Language: English

Publisher: BMJ

Publication Date: 2009

detail.hit.zdb_id: 1481557-6

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The Role of Biomass Elemental Composition and Ion-Exchange in Metal Sorption from Wastewaters Onto Algae

Carreira, Ana R. F. ; Veloso, Telma ; Macário,, Inês P. E. ; [et al.]

Elsevier BV ; 2022

In: SSRN Electronic Journal

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In: SSRN Electronic Journal, Elsevier BV

Type of Medium: Online Resource

ISSN: 1556-5068

URL: Article

DOI: 10.2139/ssrn.4222728

Language: English

Publisher: Elsevier BV

Publication Date: 2022

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Berlin Brandenburg