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Genome-Wide Association Study of Treatment Refractory Schizophrenia in Han Chinese

Liou, Ying-Jay ; Wang, Hui-Hung ; Lee, Ming-Ta Michael ; [et al.]

Public Library of Science (PLoS) ; 2012

In: PLoS ONE Vol. 7, No. 3 ( 2012-3-27), p. e33598-

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In: PLoS ONE, Public Library of Science (PLoS), Vol. 7, No. 3 ( 2012-3-27), p. e33598-

Type of Medium: Online Resource

ISSN: 1932-6203

URL: Article

DOI: 10.1371/journal.pone.0033598

DOI: 10.1371/journal.pone.0033598.g001

DOI: 10.1371/journal.pone.0033598.g002

DOI: 10.1371/journal.pone.0033598.g003

DOI: 10.1371/journal.pone.0033598.g004

DOI: 10.1371/journal.pone.0033598.t001

DOI: 10.1371/journal.pone.0033598.t002

DOI: 10.1371/journal.pone.0033598.t003

DOI: 10.1371/journal.pone.0033598.s001

DOI: 10.1371/journal.pone.0033598.s002

DOI: 10.1371/journal.pone.0033598.s003

DOI: 10.1371/journal.pone.0033598.s004

DOI: 10.1371/journal.pone.0033598.s005

DOI: 10.1371/journal.pone.0033598.s006

DOI: 10.1371/journal.pone.0033598.s007

DOI: 10.1371/journal.pone.0033598.s008

DOI: 10.1371/journal.pone.0033598.s009

DOI: 10.1371/journal.pone.0033598.s010

DOI: 10.1371/journal.pone.0033598.s011

DOI: 10.1371/journal.pone.0033598.s012

DOI: 10.1371/journal.pone.0033598.s013

DOI: 10.1371/journal.pone.0033598.s014

DOI: 10.1371/journal.pone.0033598.s015

DOI: 10.1371/journal.pone.0033598.s016

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2012

detail.hit.zdb_id: 2267670-3

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Association of altered cardiac autonomic function with psychopathology and metabolic profiles in schizophrenia

Chung, Ming-Shun ; Yang, Albert C. ; Lin, Yu-Chung ; [et al.]

Elsevier BV ; 2013

In: Psychiatry Research Vol. 210, No. 3 ( 2013-12), p. 710-715

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In: Psychiatry Research, Elsevier BV, Vol. 210, No. 3 ( 2013-12), p. 710-715

Type of Medium: Online Resource

ISSN: 0165-1781

URL: Article

DOI: 10.1016/j.psychres.2013.07.034

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2013

detail.hit.zdb_id: 1500675-X

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Association of Pulmonary Tuberculosis and Ethambutol With Incident Depressive Disorder : A Nationwide, Population-Based Cohort Study

Yen, Yung-Feng ; Chung, Ming-Shun ; Hu, Hsiao-Yun ; [et al.]

Physicians Postgraduate Press, Inc ; 2015

In: The Journal of Clinical Psychiatry Vol. 76, No. 04 ( 2015-04-22), p. e505-e511

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In: The Journal of Clinical Psychiatry, Physicians Postgraduate Press, Inc, Vol. 76, No. 04 ( 2015-04-22), p. e505-e511

Type of Medium: Online Resource

ISSN: 0160-6689

URL: Article

DOI: 10.4088/JCP.14m09403

RVK:

XA 10000

Language: English

Publisher: Physicians Postgraduate Press, Inc

Publication Date: 2015

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Effects of empiric antibiotic treatment based on hospital cumulative antibiograms in patients with bacteraemic sepsis: a retrospective cohort study

Chang, Chia-Ming ; Hsieh, Ming-Shun ; Yang, Chi-Ju ; [et al.]

Elsevier BV ; 2023

In: Clinical Microbiology and Infection Vol. 29, No. 6 ( 2023-06), p. 765-771

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In: Clinical Microbiology and Infection, Elsevier BV, Vol. 29, No. 6 ( 2023-06), p. 765-771

Type of Medium: Online Resource

ISSN: 1198-743X

URL: Article

DOI: 10.1016/j.cmi.2023.01.004

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 2020034-1

SSG: 12

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Effect of Carbon Monoxide Poisoning on Epilepsy Development: A Nationwide Population-Based Cohort Study

Meng, Yu-Hsiang ; Hsieh, Ming-Shun ; Chi, Yu-Chi ; [et al.]

Elsevier BV ; 2023

In: Annals of Emergency Medicine Vol. 82, No. 2 ( 2023-08), p. 145-151

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In: Annals of Emergency Medicine, Elsevier BV, Vol. 82, No. 2 ( 2023-08), p. 145-151

Type of Medium: Online Resource

ISSN: 0196-0644

URL: Article

DOI: 10.1016/j.annemergmed.2022.11.021

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 2003465-9

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A rapid screening test for depression in junior high school children

Chung, Ming-Shun ; Chiu, Hsien-Jane ; Sun, Wen-Jung ; [et al.]

Ovid Technologies (Wolters Kluwer Health) ; 2011

In: Journal of the Chinese Medical Association Vol. 74, No. 8 ( 2011-08), p. 363-368

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In: Journal of the Chinese Medical Association, Ovid Technologies (Wolters Kluwer Health), Vol. 74, No. 8 ( 2011-08), p. 363-368

Type of Medium: Online Resource

ISSN: 1726-4901

URL: Article

DOI: 10.1016/j.jcma.2011.06.007

Language: English

Publisher: Ovid Technologies (Wolters Kluwer Health)

Publication Date: 2011

detail.hit.zdb_id: 2202774-9

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Hospital outcomes and cumulative burden from complications in type 2 diabetic sepsis patients: a cohort study using administrative and hospital-based databases

Hsieh, Ming-Shun ; Hu, Sung-Yuan ; How, Chorng-Kuang ; [et al.]

SAGE Publications ; 2019

In: Therapeutic Advances in Endocrinology and Metabolism Vol. 10 ( 2019-01), p. 204201881987540-

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In: Therapeutic Advances in Endocrinology and Metabolism, SAGE Publications, Vol. 10 ( 2019-01), p. 204201881987540-

Abstract: The association between type 2 diabetes and hospital outcomes of sepsis remains controversial when severity of diabetes is not taken into consideration. We examined this association using nationwide and hospital-based databases. Methods: The first part of this study was mainly conducted using a nationwide database, which included 1.6 million type 2 diabetic patients. The diabetic complication burden was evaluated using the adapted Diabetes Complications Severity Index score (aDCSI score). In the second part, we used laboratory data from a distinct hospital-based database to make comparisons using regression analyses. Results: The nationwide study included 19,719 type 2 diabetic sepsis patients and an equal number of nondiabetic sepsis patients. The diabetic sepsis patients had an increased odds ratio (OR) of 1.14 (95% confidence interval 1.1–1.19) for hospital mortality. The OR for mortality increased as the complication burden increased [aDCSI scores of 0, 1, 2, 3, 4, and ⩾5 with ORs of 0.91, 0.87, 1.14, 1.25, 1.56, and 1.77 for mortality, respectively (all p 〈 0.001)]. The hospital-based database included 1054 diabetic sepsis patients. Initial blood glucose levels did not differ significantly between the surviving and deceased diabetic sepsis patients: 273.9 ± 180.3 versus 266.1 ± 200.2 mg/dl ( p = 0.095). Moreover, the surviving diabetic sepsis patients did not have lower glycated hemoglobin (HbA1c; %) values than the deceased patients: 8.4 ± 2.6 versus 8.0 ± 2.5 ( p = 0.078). Conclusions: For type 2 diabetic sepsis patients, the diabetes-related complication burden was the major determinant of hospital mortality rather than diabetes per se, HbA1c level, or initial blood glucose level.

Type of Medium: Online Resource

ISSN: 2042-0188 , 2042-0196

URL: Article

DOI: 10.1177/2042018819875406

Language: English

Publisher: SAGE Publications

Publication Date: 2019

detail.hit.zdb_id: 2554822-0

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Clinical features, management, and outcome of iliopsoas abscess associated with cardiovascular disorders: a hospital-based observational case series study

Hu, Sung-Yuan ; Hsieh, Ming-Shun ; Chang, Yao-Tien ; [et al.]

Springer Science and Business Media LLC ; 2019

In: BMC Musculoskeletal Disorders Vol. 20, No. 1 ( 2019-12)

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In: BMC Musculoskeletal Disorders, Springer Science and Business Media LLC, Vol. 20, No. 1 ( 2019-12)

Abstract: Iliopsoas abscess (IPA) is a rare clinical entity and is difficult to diagnose due to its insidious onset and nonspecific symptoms. The association between IPA and cardiovascular disorders (CVD) has been rarely reported. Computed tomographic (CT) scan can provide a definitive diagnosis of IPA and associated foci of adjacent structures. IPA is a life-threatening condition, especially when associated with CVD. Materials and methods We conducted a hospital-based observational study of IPA associated with CVD. Data were collected from the electronic clinical database of Taichung Veterans General Hospital (1520-bed tertiary referral hospital in central Taiwan) between July 2007 and December 2017. The diagnosis of IPA associated with CVD was confirmed by classical findings on CT and transesophageal echocardiography with compatible clinical presentation and cultures from pus/tissue and blood. Results Fifteen patients of IPA associated with CVD were studied. They included 12 males (80%) and 3 females (20%), with a mean age 63.2 ± 16.9 years (31–85 years). CVD included stent-graft/endograft infection of abdominal aortic aneurysm (AAA) (40%), primary mycotic AAA (33.3%), and infective endocarditis (26.7%). Staphylococcus aureus is the most common microorganism in pus/tissue cultures ( n = 3, 37.5%) and in blood cultures ( n = 6, 40%). The average length of hospital stay was 33.1 ± 20.5 days (range, 3–81 days; median, 33 days). Hospital stay lasted 42.6 ± 19.2 days in the survival group and 19.0 ± 14.1 days ( P = 0.018) in the non-survival group. Incidence of patients staying in the intensive care unit (ICU) with intubation 〉 3 days was 33% in the survival group and 100% ( P = 0.028) in the non-survival group. Intra-hospital mortality rate was 40%. Poor prognostic factors in the non-survival group were hypoalbuminemia, hyponatremia, involved disc/vertebral body and/or epidural abscess, and ICU stay with intubation 〉 3 days. Cumulative survival rate was 25% under conservative treatments and 66.3% under aggressive treatments ( P = 0.038). Conclusion Due to high mortality rates, clinicians should keep a high suspicion index for IPA associated with CVD through clinical presentation, physical examination, and imaging study. Timely empiric antibiotics for common bacteria, drainage for IPA, endovascular repair, or vascular reconstruction by graft replacement or bypass with intensive care should be mandatory to shorten the hospital stay, reduce medical costs, and lower mortality rate.

Type of Medium: Online Resource

ISSN: 1471-2474

URL: Article

DOI: 10.1186/s12891-019-2798-3

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2019

detail.hit.zdb_id: 2041355-5

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Associations between daily steps and cognitive function among inpatients with schizophrenia

Chen, Li-Jung ; Stubbs, Brendon ; Chien, I-Chia ; [et al.]

Springer Science and Business Media LLC ; 2022

In: BMC Psychiatry Vol. 22, No. 1 ( 2022-12)

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In: BMC Psychiatry, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)

Abstract: Walking is the fundamental component of taking steps and is the main form of physical activity among individuals with schizophrenia; it also offers a range of health benefits. This study aimed to examine the associations between daily steps and cognitive function and further explored how many steps were related to better cognitive function among inpatients with schizophrenia. Methods Inpatients with schizophrenia were recruited from long-stay psychiatric wards across two hospitals (n=199 at site 1 and n=195 at site 2). Daily steps were collected with an accelerometer for 7 days. Four cognitive domains (attention, processing speed, reaction time, and motor speed) were tested at site 1, and two cognitive domains (attention and processing speed) were tested at site 2. The associations of daily steps and levels of steps/day with cognitive function were tested using multivariable linear regressions separated by site. Covariates included demographic variables, weight status, metabolic parameters, and clinical state. Results Participants took an average of 7445 (±3442) steps/day. More steps were related to better attention, processing speed, reaction time, and motor speed after multivariable adjustments. Compared with participants taking 〈 5000 steps/day, those taking ≥5000 steps/day showed significantly better processing speed. Participants taking ≥7500 steps/day were associated with better attention, better reaction time, and better motor speed than those taking 〈 5000 steps/day. Conclusion Daily steps are associated with better cognitive function among inpatients with schizophrenia. The optimal benefit for cognitive function among this clinical population is achieving 7500 steps/day or more.

Type of Medium: Online Resource

ISSN: 1471-244X

URL: Article

DOI: 10.1186/s12888-022-03736-2

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2022

detail.hit.zdb_id: 2050438-X

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Association among depressive disorder, adjustment disorder, sleep disturbance, and suicidal ideation in Taiwanese adolescent : Factors for adolescent suicidal ideation

Chung, Ming-Shun ; Chiu, Hsien-Jane ; Sun, Wen-Jung ; [et al.]

Wiley ; 2014

In: Asia-Pacific Psychiatry Vol. 6, No. 3 ( 2014-09), p. 319-325

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In: Asia-Pacific Psychiatry, Wiley, Vol. 6, No. 3 ( 2014-09), p. 319-325

Type of Medium: Online Resource

ISSN: 1758-5864

URL: Issue

URL: Article

DOI: 10.1111/appy.2014.6.issue-3

DOI: 10.1111/appy.12112

Language: English

Publisher: Wiley

Publication Date: 2014

detail.hit.zdb_id: 2506343-1

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