In:
International Journal of Cancer, Wiley, Vol. 139, No. 2 ( 2016-07-15), p. 404-413
Abstract:
What's New? The formation of new blood vessels is a crucial step in tumor growth and progression. In this study, the authors used an imaging method called DCE‐MRI to study tumor angiogenesis in a mouse model of breast cancer. They saw a significant increase in DCE‐MRI biomarkers during malignant transformation. This “angiogenic switch” coincided with an increase in vessel permeability and plasma volume, and histology confirmed that the number of microvessels had increased. These results suggest that DCE‐MRI may be a valuable tool for early, non‐invasive detection of breast cancer.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
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