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  • 1
    Online Resource
    Online Resource
    Preoperative, intraoperative, and postoperative assessment of corneal biomechanics in refractive surgery
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Current Opinion in Ophthalmology Vol. 31, No. 4 ( 2020-07), p. 234-240
    Details
    In: Current Opinion in Ophthalmology, Ovid Technologies (Wolters Kluwer Health), Vol. 31, No. 4 ( 2020-07), p. 234-240
    Abstract: To review current and emerging methods and utilities of preoperative, intraoperative, and postoperative measurements of corneal biomechanics and their effects on refractive surgery decision-making. Recent findings Several recent clinical and preclinical studies have demonstrated the utility of corneal biomechanical analysis in refractive surgery. These studies focus on both screening surgical candidates for keratoconic disease as well as intraoperative and postoperative monitoring. The measurement of spatially resolved biomechanics is beginning to be studied in humans. Summary Clinically available screening methods combining corneal biomechanics with topographic and tomographic data provide increased utility when screening for keratoconic disorder. Spatially resolved measurement of corneal biomechanics holds great potential for preoperative, intraoperative, and postoperative evaluation of refractive surgery candidates as well as for more individualized procedures in the future.
    Type of Medium: Online Resource
    ISSN: 1040-8738 , 1531-7021
    URL: Article
    DOI: 10.1097/ICU.0000000000000663
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2026983-3
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  • 2
    Online Resource
    Online Resource
    Transepithelial Corneal Crosslinking Using a Novel Ultraviolet Light-Emitting Contact Lens Device: A Pilot Study
    Association for Research in Vision and Ophthalmology (ARVO) ; 2021
    In:  Translational Vision Science & Technology Vol. 10, No. 5 ( 2021-04-29), p. 5-
    Details
    In: Translational Vision Science & Technology, Association for Research in Vision and Ophthalmology (ARVO), Vol. 10, No. 5 ( 2021-04-29), p. 5-
    Type of Medium: Online Resource
    ISSN: 2164-2591
    URL: Article
    DOI: 10.1167/tvst.10.5.5
    Language: English
    Publisher: Association for Research in Vision and Ophthalmology (ARVO)
    Publication Date: 2021
    detail.hit.zdb_id: 2674602-5
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  • 3
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    Online Resource
    The Relationship Between Corneal Biomechanics and Intraocular Pressure Dynamics in Patients Undergoing Intravitreal Injection
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Journal of Glaucoma Vol. 30, No. 5 ( 2021-05), p. 451-458
    Details
    In: Journal of Glaucoma, Ovid Technologies (Wolters Kluwer Health), Vol. 30, No. 5 ( 2021-05), p. 451-458
    Abstract: A higher “corneal resistance factor” (CRF) was associated with greater intraocular pressure (IOP) elevation after intravitreal injection of bevacizumab. Both higher “corneal hysteresis” (CH) and CRF were associated with more rapid IOP recovery postinjection. Purpose: The purpose of this study was to evaluate the relationship between measurable corneal biomechanical properties and acute IOP elevation after rapid intraocular volume expansion from the routine intravitreal injection. Materials and Methods: A total of 100 patients necessitating unilateral intravitreal injection with 0.05 mL of bevacizumab for retinal pathology were analyzed before injection with Goldmann Applanation Tonometry to measure IOP, Ocular Response Analyzer (ORA) to measure corneal biomechanical properties, and optical biometry to calculate globe measurements. IOP and ORA were measured again within 5 minutes of the injection and then IOP measurements were taken every 10 minutes until the IOP was ≤150% of the preinjection IOP. Linear regression and logistic regression were used to test variables associated with acute IOP increase. A Cox proportional hazard model accounting for preinjection IOP and postinjection IOP was used to test the effect of CH or CRF on the time required to return to 150% of baseline IOP. Results: Higher CRF was associated with greater immediate postinjection IOP ( P =0.026) elevation. A preinjection IOP 〉 15.5 mm Hg moderately predicted postinjection IOP≥35 mm Hg (area under the receiver operating characteristics curve=0.74). A preinjection IOP 〉 18.5 mm Hg combined with CH poorly predicted postinjection IOP 〉 50 mm Hg (area under the receiver operating characteristics curve=0.67). A higher CH [hazard ratio (HR)=1.24; 95% confidence interval (CI)=1.08-1.42; P =0.002] and preinjection IOP (HR=1.16; 95% CI=1.09-1.22; P 〈 0.001), along with a lower immediate postinjection IOP (HR=0.93; 95% CI=0.90-0.95; P 〈 0.001), were each independently associated with quicker IOP recovery postinjection. Similar results were seen in the Cox model examining CRF and IOP recovery. Conclusions: Higher CRF and preinjection IOP were independently associated with greater postinjection IOP elevations. ORA metrics did not greatly strengthen the prediction of patients who would have postinjection IOP 〉 50 mm Hg. Higher CH and CRF were associated with faster IOP recovery after intravitreal injection, demonstrating the dynamic relationship between ocular biomechanical properties and aqueous outflow pathways.
    Type of Medium: Online Resource
    ISSN: 1057-0829
    URL: Article
    DOI: 10.1097/IJG.0000000000001833
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 2060541-9
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