In:
Current Neurovascular Research, Bentham Science Publishers Ltd., Vol. 19, No. 4 ( 2022-08), p. 418-426
Abstract:
Most studies of cerebral microbleeds place more emphasis on
the elderly, which made it difficult to obtain data on youth, particularly young ischemic stroke patients. Our study sought to investigate the incidence and related risk factors of cerebral microbleeds
in young ischemic stroke patients. Methods: Young ischemic stroke patients who sought medical advice at Beijing Chaoyang Hospital
between June 2016 and September 2020 were included in our study. The clinical and imaging data of these patients were collected and assessed. These patients were grouped by cerebral microbleed
presence, count, and location. Univariate and multivariate logistic regression analyses were performed to investigate the association between these groups and screen the influencing factors of
cerebral microbleeds in young patients with ischemic stroke. Results: Among the 187 young ischemic stroke patients, the prevalence of microbleeds was 16%.
The presence of cerebral microbleeds was associated with hypertension (odds ratio [OR] 8.787, 95%
confidence interval [CI] 1.016-76.006, P=0.048), lower estimated glomerular filtration rate (OR
0.976, 95%CI 0. 957-0.995, P=0.014) and moderate/severe white matter hyperintensity (OR 10.681,
95%CI 3.611-31.595, P 〈 0.001) in young ischemic stroke patients. Conclusion: Cerebral microbleeds were common in young ischemic stroke patients and were associated
with hypertension, lower estimated glomerular filtration rate, and moderate/severe white matter hyperintensity.
Type of Medium:
Online Resource
ISSN:
1567-2026
DOI:
10.2174/1567202620666221102125214
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
2022
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