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  • 1
    Online Resource
    Online Resource
    EDP Sciences ; 2019
    In:  EPJ Web of Conferences Vol. 209 ( 2019), p. 01008-
    In: EPJ Web of Conferences, EDP Sciences, Vol. 209 ( 2019), p. 01008-
    Abstract: The Pierre Auger Observatory has been very successful in determining many aspects of the highest-energy cosmic rays including, among others, the flux suppression at energies above 4 × 10 19 eV, stringent upper limits on photon and neutrino fluxes at ultra-high energies and an unexpected evolution of the mass composition with energy. We expect an extension of the frontiers of our knowledge on these aspects from a major upgrade of the Observatory. The upgrade, known as AugerPrime, will include an addition of a 4 m 2 Surface Scintillator Detector atop each water-Cherenkov station of the Surface array. The new detectors will provide us with an unprecedented opportunity to perform a complementary measurement of the shower particles and thus determine the primary mass composition with good accuracy on an event-by-event basis. AugerPrime will also include an upgrade of electronics, installation of the AMIGA Underground Muon Detector and a change of observation mode of the Fluorescence Detector, which will increase its current duty cycle by about 50%. Current status of the upgrade with the main focus on the Surface Scintillator Detectors will be presented, following a brief description of the physics motivation for the upgrade.
    Type of Medium: Online Resource
    ISSN: 2100-014X
    Language: English
    Publisher: EDP Sciences
    Publication Date: 2019
    detail.hit.zdb_id: 2595425-8
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  • 2
    In: Symmetry, MDPI AG, Vol. 12, No. 11 ( 2020-11-05), p. 1835-
    Abstract: The Cosmic-Ray Extremely Distributed Observatory (CREDO) is a newly formed, global collaboration dedicated to observing and studying cosmic rays (CR) and cosmic-ray ensembles (CRE): groups of at least two CR with a common primary interaction vertex or the same parent particle. The CREDO program embraces testing known CR and CRE scenarios, and preparing to observe unexpected physics, it is also suitable for multi-messenger and multi-mission applications. Perfectly matched to CREDO capabilities, CRE could be formed both within classical models (e.g., as products of photon–photon interactions), and exotic scenarios (e.g., as results of decay of Super-Heavy Dark Matter particles). Their fronts might be significantly extended in space and time, and they might include cosmic rays of energies spanning the whole cosmic-ray energy spectrum, with a footprint composed of at least two extensive air showers with correlated arrival directions and arrival times. As the CRE are predominantly expected to be spread over large areas and, due to the expected wide energy range of the contributing particles, such a CRE detection might only be feasible when using all available cosmic-ray infrastructure collectively, i.e., as a globally extended network of detectors. Thus, with this review article, the CREDO Collaboration invites the astroparticle physics community to actively join or to contribute to the research dedicated to CRE and, in particular, to pool together cosmic-ray data to support specific CRE detection strategies.
    Type of Medium: Online Resource
    ISSN: 2073-8994
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2518382-5
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  • 3
    In: Universe, MDPI AG, Vol. 8, No. 10 ( 2022-09-22), p. 498-
    Abstract: Both the lack of observation of ultra-high energy (UHE) photons and the limitations of the state-of-the-art methodology being applied for their identification motivate studies on alternative approaches to the relevant simulations and the related observational strategies. One such new approach is proposed in this report and it concerns new observables allowing indirect identification of UHE photons through cosmic ray phenomena composed of many spatially correlated extensive air showers or primary cosmic rays observed at one time. The study is based on simulations of interactions of UHE photons with the magnetic field of the Sun using the PRESHOWER program with some essential modifications. One of the expected results of such interactions is a generation of cosmic ray ensembles (CREs) in the form of very thin and very elongated cascades of secondary photons of energies spanning the whole cosmic ray energy spectrum. Upon entering the Earth’s atmosphere, these cascades or their parts may generate uniquely characteristic walls of spatially correlated extensive air showers, and the effect is expected also in cases when primary UHE photons are not directed towards the Earth. Particle distributions in these multi-primary UHE photon footprints are expected to have thicknesses of the order of meters and elongations reaching even hundreds of millions of kilometers, making them potentially observable with a global, multi-experiment approach, including re-exploring of the historical data, with the expected event rate exceeding the capabilities of even very large cosmic ray observatories. In this report, we introduce for the first time the methods allowing for simulating the isotropic flux of UHE photons in the Sun’s vicinity. Presented methods were verified and optimised in such a way that they would successfully model the cumulative spatial distribution of secondary photons at the top of the atmosphere. The preliminary results of simulations for the UHE photon flux of energy 100 EeV demonstrate the possibility of simulating potentially observable quantities related to CRE induced by UHE photons: densities, energy spectra and geographical orientations of secondary particles at the top of the Earth’s atmosphere. A measurement of at least one of these quantities would be equivalent to a confirmation of the existence of UHE photons, which would give an insight into fundamental physics processes at unprecedentedly high energies, far beyond the reach of man-made accelerators. On the other hand, a lack of such an observation would allow for further constraining of these fundamental processes with the physically new upper limits on UHE photon fluxes after careful analysis of the technical observation ability. The novel advantage of such an approach would lay in the purely electrodynamical character of the underlying simulations which are fully independent on extrapolations of hadronic interaction models by many orders of magnitude. Such extrapolations are necessary in the UHE photon identification methods based on the analyses of properties of individual extensive air showers presently used to determine the UHE photon upper limits.
    Type of Medium: Online Resource
    ISSN: 2218-1997
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2813994-X
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  • 4
    Online Resource
    Online Resource
    American Astronomical Society ; 2023
    In:  The Astrophysical Journal Vol. 955, No. 2 ( 2023-10-01), p. 121-
    In: The Astrophysical Journal, American Astronomical Society, Vol. 955, No. 2 ( 2023-10-01), p. 121-
    Abstract: Blazars exhibit relentless variability across diverse spatial and temporal frequencies. The study of long- and short-term variability properties observed in the X-ray band provides insights into the inner workings of the central engine. In this work, we present timing and spectral analyses of the blazar 3C 273 using the X-ray observations from the XMM-Newton telescope covering the period from 2000 to 2020. The methods of timing analyses include estimation of fractional variability, long- and short-term flux distribution, rms–flux relation, and power spectral density analysis. The spectral analysis include estimating a model-independent flux hardness ratio and fitting the observations with multiplicative and additive spectral models such as power law , log-parabola , broken power law , and blackbody . The blackbody represents the thermal emission from the accretion disk, while the other models represent the possible energy distributions of the particles emitting synchrotron radiation in the jet. During the past two decades, the source flux changed by a factor of three, with a considerable fractional variability of 27%. However, the intraday variation was found to be moderate. Flux distributions of the individual observations were consistent with a normal or log-normal distribution, while the overall flux distribution including all observations appears to be rather multimodal and of a complex shape. The spectral analyses indicate that a log-parabola added to a blackbody gives the best fit for most of the observations. The results indicate a complex scenario in which the variability can be attributed to the intricate interaction between the disk/corona system and the jet.
    Type of Medium: Online Resource
    ISSN: 0004-637X , 1538-4357
    RVK:
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2023
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 1473835-1
    SSG: 16,12
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  • 5
    In: Astroparticle Physics, Elsevier BV, Vol. 123 ( 2020-12), p. 102489-
    Type of Medium: Online Resource
    ISSN: 0927-6505
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 1499883-X
    SSG: 16,12
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  • 6
    In: Journal of Institute of Medicine Nepal, Institute of Medicine, Nepal, Vol. 42, No. 1 ( 2020-04-30), p. 31-35
    Abstract: Introduction Laparoscopic donor nephrectomy is the gold standard for kidney retrieval in live donors. Until recently, donor nephrectomies were performed only by open technique in Nepal. There is no information on the experience and outcomes of laparoscopic donor nephrectomy in Nepal. The study was done to compare the outcomes among donors undergoing open and laparoscopic nephrectomies, and to compare the graft related outcomes between the two groups receiving these kidneys. MethodsIn this retrospective study, 44 kidney donors from March 2019 to October 2019 were analyzed. Donors were divided into 2 groups: open donor nephrectomy (ODN) and laparoscopic donor nephrectomy (LDN). Parameters for analysis included demographic data, warm ischemia time, surgery time and length of hospital stay. Data on early graft function and complications in recipients till 30th post-operative day were compared. ResultsThere were 22 donors each in the ODN and LDN groups. Baseline characteristics of the donors were comparable between two groups. Mean surgery duration (183.55±43.31 minutes vs 117.73±18.75 minutes) and first warm ischemia time (11.22±4.34 minutes vs 2.3±0.8 minutes) was significantly high in LDN. Hemoglobin drop, post-operative complications in donors, creatinine of donors at discharge, mean hospital stay, graft function at one month and complications in recipients were comparable among ODN and LDN. Pain score in 1st post-operative day was comparable between two groups, however, pain was significantly less in second post-operative day in LDN. ConclusionLaparoscopic donor nephrectomy is feasible in Nepal and associated with acceptable morbidity and graft function when compared to ODN.
    Type of Medium: Online Resource
    ISSN: 1993-2987 , 1993-2979
    Language: Unknown
    Publisher: Institute of Medicine, Nepal
    Publication Date: 2020
    detail.hit.zdb_id: 2481677-2
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  • 7
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2022
    In:  Monthly Notices of the Royal Astronomical Society Vol. 510, No. 4 ( 2022-01-21), p. 5280-5301
    In: Monthly Notices of the Royal Astronomical Society, Oxford University Press (OUP), Vol. 510, No. 4 ( 2022-01-21), p. 5280-5301
    Abstract: The X-ray emission from blazars has been widely investigated using several space telescopes. In this work, we explored statistical properties of the X-ray variability in the blazars S5 0716+714, OJ 287, Mkn 501, and RBS 2070 using the archival observations from the XMM-Newton telescope between the period 2002–2020. Several methods of timing and spectral analyses, including fractional variability, minimum variability time-scale, power spectral density analyses, and countrate distribution, were performed. In addition, we fitted various spectral models to the observations, as well as estimated hardness ratio. The results show that the sources are moderately variable within the intraday time-scale. Three of the four sources exhibited a clear bi-modal pattern in their countrate distribution, revealing possible indication of two distinct countrate states, that is, hard and soft countrate states. The slope indices of the power spectral density were found to be centred around 0.5. Furthermore, the spectra of the sources were fitted with single power law, broken power law, log-parabolic, and blackbody + log-parabolic models (the latter only for OJ 287). We conclude that for most of the observations log-parabolic model was the best fit. The power-spectral-density analysis revealed the variable nature of PSD slopes in the source light curves. The results of this analysis could indicate the non-stationary nature of the blazar processes on intraday time-scales. The observed features can be explained within the context of current blazar models, in which the non-thermal emission mostly arises from kilo-pc scale relativistic jets.
    Type of Medium: Online Resource
    ISSN: 0035-8711 , 1365-2966
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2016084-7
    SSG: 16,12
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  • 8
    Online Resource
    Online Resource
    American Astronomical Society ; 2020
    In:  The Astrophysical Journal Vol. 891, No. 2 ( 2020-03-12), p. 120-
    In: The Astrophysical Journal, American Astronomical Society, Vol. 891, No. 2 ( 2020-03-12), p. 120-
    Type of Medium: Online Resource
    ISSN: 1538-4357
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2020
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 1473835-1
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  • 9
    Online Resource
    Online Resource
    Nepal Journals Online (JOL) ; 2023
    In:  BIBECHANA Vol. 20, No. 1 ( 2023-04-05), p. 55-64
    In: BIBECHANA, Nepal Journals Online (JOL), Vol. 20, No. 1 ( 2023-04-05), p. 55-64
    Abstract: This research work was carried out to analyze the X-ray flares in Blazar Mkn 421 using data from XMM-Newton observation (Observation ID: 0658801301) that lasted for 8 hours. EPIC/pn data was used for statistical analysis of the light and spectrum curve in energy ranges from 0.3 to 10.0 keV. The best fit model for the spectrum was found to be the additive model (log-parabola + black-body). The measured integrated flux in the energy range of 0.3-2 keV is  5.015x10-10 ergs cm-2 s-1 with an associated uncertainty range of (5.010 – 5.020) x 10-10 ergs cm-2 s-1 at a 90% confidence level. Similarly, the measured integrated flux in the energy range of 2-10 keV is 2.398 x  10-10 ergs cm-2 s-1 with an associated uncertainty range of (2.392 – 2.405) x  10-10 ergs cm-2 s-1 at a 90% confidence level. The fractional variability of 0.444 is relatively high, which indicates that the source is variable. The fall in count per second per energy around 2 keV in the spectrum curve suggests that the intensity of X-rays decreases in a power law manner after a strong flare at this energy. The count-rate distribution of the observation analyzed is best described by a normal distribution which suggests that the emission mechanism in the blazar is governed by additive processes.
    Type of Medium: Online Resource
    ISSN: 2382-5340 , 2091-0762
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2023
    detail.hit.zdb_id: 2861633-9
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  • 10
    In: BioMed Research International, Hindawi Limited, Vol. 2016 ( 2016), p. 1-8
    Abstract: Introduction. Pseudomonas aeruginosa is the most frequently isolated organism as it acts as the opportunistic pathogen and can cause infections in immunosuppressed patients. The production of different types of beta-lactamases renders this organism resistant to many commonly used antimicrobials. Therefore, the aim of this study was to document the antibiotic resistance rate in Pseudomonas aeruginosa isolated from different clinical specimens. Methods. Pseudomonas aeruginosa recovered was identified by standard microbiological methods. Antibiotic susceptibility testing was performed by modified Kirby-Bauer disc diffusion method following Clinical and Laboratory Standard Institute (CLSI) guidelines and all the suspected isolates were tested for the production of ESBLs, MBLs, and AmpC. Results. Out of total (178) isolates, 83.1% were recovered from the inpatient department (IPD). Majority of the isolates mediated resistance towards the beta-lactam antibiotics, while nearly half of the isolates were resistant to ciprofloxacin. Most of the aminoglycosides used showed resistance rate up to 75% but amikacin proved to be better option. No resistance to polymyxin was observed. ESBLs, MBLs, and AmpC mediated resistance was seen in 33.1%, 30.9%, and 15.7% isolates, respectively. Conclusions . Antibiotic resistance rate and beta-lactamase mediated resistance were high. Thus, regular surveillance of drug resistance is of utmost importance.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2698540-8
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