In:
Italian Journal of Medicine, PAGEPress Publications, Vol. 9, No. 3 ( 2015-10-05)
Abstract:
We describe a 39-year-old male who presented with a fever of unknown origin the diagnostic work-up of which disclosed an acute CMV infection complicated by a partial superior mesenteric vein (SMV) thrombosis. Further investigations revealed the presence of factor V Leiden mutation. Oral anticoagulant treatment with warfarin lead to a complete recanalization of SMV two months after. A literature review on the association between CMV infection and portal system (PS) thrombosis in immunocompetent patients was performed. We found that, in agreement with our case, in a minority of case reports patients did not complain of abdominal pain, but presented with a mononucleosic-like syndrome with malaise and prolonged fever and displayed a variable elevation of aminotransferase levels. Interestingly, most of them exhibited a limited extension of portal thrombosis. On the whole, these data suggest that PS thrombosis during acute CMV infection may be an underestimated complication.
Type of Medium:
Online Resource
ISSN:
1877-9352
,
1877-9344
DOI:
10.4081/itjm.2015.596
Language:
Unknown
Publisher:
PAGEPress Publications
Publication Date:
2015
detail.hit.zdb_id:
2515650-0
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