In:
Digestive Surgery, S. Karger AG, Vol. 35, No. 1 ( 2018), p. 35-41
Abstract:
〈 b 〉 〈 i 〉 Background/Aims: 〈 /i 〉 〈 /b 〉 Several initiatives have started to transfer colorectal cancer follow-up (FU) from secondary to primary care. For this purpose, it is important to assess when and how recurrences of rectal carcinoma are detected after treatment with curative intent. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Retrospective multicentre cohort study. Patients participating in an FU programme after curative intended treatment for rectal cancer stages I-III between 2007 and 2014. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Of the 378 patients, 64 (17%) developed recurrent disease (RD). Most were detected during scheduled FU consultations ( 〈 i 〉 n 〈 /i 〉 = 55) by (a combination of) radiological examinations and carcinoembryonic antigen levels, and were asymptomatic ( 〈 i 〉 n 〈 /i 〉 = 53); outside scheduled FU consultations, RD was detected during the treatment of postoperative complications or ostomy reversal ( 〈 i 〉 n 〈 /i 〉 = 5), or due to symptoms ( 〈 i 〉 n 〈 /i 〉 = 4). Most frequent sites of recurrence were liver (50%), lung (44%), multiple (22%) or locoregional (16%). Treatment of RD with curative intent was performed more frequently when detected during scheduled FU (60 vs. 22%). The only predictive factor for developing RD was stage III disease on initial presentation. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 The majority of rectal cancer patients are diagnosed with RD at an asymptomatic stage during scheduled FU consultations. Only a few patients presented with RD outside the FU programme. Arguably, general practitioners could order these same diagnostic tests during FU.
Type of Medium:
Online Resource
ISSN:
0253-4886
,
1421-9883
Language:
English
Publisher:
S. Karger AG
Publication Date:
2018
detail.hit.zdb_id:
605888-7
detail.hit.zdb_id:
1468560-7
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