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  • 1
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2021
    In:  coloproctology Vol. 43, No. 5 ( 2021-10), p. 352-362
    In: coloproctology, Springer Science and Business Media LLC, Vol. 43, No. 5 ( 2021-10), p. 352-362
    Abstract: Die ileopouchanale Anastomose (IPAA) ist Goldstandard bei der Proktokolektomie. Ziel der vorliegenden Untersuchung ist es, die chirurgischen Ergebnisse der Operationen des Autors einschließlich Pouchüberleben und Lebensqualität über 30 Jahre zu überprüfen. Methodik Retrospektiv wurden die Krankenunterlagen von Patienten, bei denen zwischen 1986 und 2015 eine IPAA angelegt wurde, zu Früh- und Spätkomplikationen sowie Pouchüberleben ausgewertet. Mit einer Online-Befragung wurde die Lebensqualität ermittelt. Ergebnisse In einer Gruppe von 119 Patienten, von denen 84 an chronisch-entzündlichen (CED) und 35 an nicht chronisch-entzündlichen Darmerkrankungen (Non-CED) litten, wurde in 69 % der Pouch simultan und in 31 % metachron zur Proktokolektomie angelegt. Bei 100 Patienten wurde eine Doppelstapleranastomose mit zusätzlicher Tabaksbeutelnaht durchgeführt. Bei temporärer transanaler Dekompression mittels Kathetereinlage bei allen wurde selektiv in 68 % auf eine Loop-Ileostomie (LIS) verzichtet. Dabei ereigneten sich 3 Anastomoseninsuffizienzen ohne (4,4 %), aber auch 3 mit (9,4 %) LIS. Die perioperative Morbidität des Verschlusses der Lis war mit 33,3 % beträchtlich. Im Langzeitverlauf erlitten 36 Patienten (30.5 %) revisionspflichtige Komplikationen, deren kumulative Auftrittswahrscheinlichkeit bereits nach 15 Jahren 59,1 % erreichte. Die IPAA musste deswegen bei 16 Patienten (13,6 %) aufgehoben werden, wodurch die kumulative Kontinenzerhaltung nach 15 Jahren auf 72,9 % sank. Da in 6 Fällen mit nicht korrigierbaren funktionellen Komplikationen der Pouch zur kontinenten Ileostomie (CI) konvertiert werden konnte, lag das kumulative Pouchüberleben nach 27 Jahren noch bei 81,8 %. Die Online-Befragung ergab für die Bereiche Beruf, Sport und Reisen eine signifikante Verbesserung gegenüber vor der Proktokolektomie, für das Sexualleben dagegen keine Veränderung. Jedoch erreichten die physischen, psychologischen und sozialen Scores nicht die Werte der gesunden Altersgruppe. Obwohl mehr als 90 % mit dem operativen Ergebnis zumindest zufrieden waren, gaben nur 3 von 25 keine funktionellen Verbesserungswünsche an. Schlussfolgerung Die IPAA in Doppelstaplertechnik ist auch ohne protektive LIS ein sicheres Operationsverfahren. Die Kurz- und Langzeitmorbidität ist allerdings beträchtlich, woraus ein nicht vernachlässigbares Risiko des Kontinenzverlusts resultiert. Durch Konversion zur CI bei rein funktionellen Komplikationen kann das definitive Pouchversagen deutlich verringert werden. Trotz großer subjektiver Zufriedenheit der Operierten bleibt ihre Lebensqualität objektiv kompromittiert.
    Type of Medium: Online Resource
    ISSN: 0174-2442 , 1615-6730
    RVK:
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2023514-8
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  • 2
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2021
    In:  coloproctology Vol. 43, No. 5 ( 2021-10), p. 363-363
    In: coloproctology, Springer Science and Business Media LLC, Vol. 43, No. 5 ( 2021-10), p. 363-363
    Type of Medium: Online Resource
    ISSN: 0174-2442 , 1615-6730
    RVK:
    Language: German
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2023514-8
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  • 3
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  International Journal of Colorectal Disease Vol. 37, No. 12 ( 2022-11-21), p. 2459-2468
    In: International Journal of Colorectal Disease, Springer Science and Business Media LLC, Vol. 37, No. 12 ( 2022-11-21), p. 2459-2468
    Abstract: Comprehensive description of surgical techniques for revision of complications of continent ileostomy (CI). Methods By analyzing 133 revision procedures performed over 30 years, a systematically classified approach to the appropriate techniques for CI revision surgery has been derived. Based on the anatomic site and severity of the respective complication, four classes of revision surgeries have been defined: class 1 refers to the nipple valve, class 2 to the pouch, class 3 to the stoma, and class 4 to the afferent loop. The severity of the complication or the complexity of the revision procedure is indicated by a subdivision from a to d. Results The surgical variants (class 1a–d, class 2a–c, class 3a–b, and class 4a–b) are shown in schematic illustrations with accompanying descriptions of technical details, the respective fields of application, and the special indications. Conclusion Based on these classes of revision surgeries, the specialized surgeon may find differentiated techniques at their disposal to save the CI and avoid unnecessary sacrifice of the artificial continence organ.
    Type of Medium: Online Resource
    ISSN: 1432-1262
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1459217-4
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  • 4
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  International Journal of Colorectal Disease Vol. 37, No. 3 ( 2022-03), p. 553-561
    In: International Journal of Colorectal Disease, Springer Science and Business Media LLC, Vol. 37, No. 3 ( 2022-03), p. 553-561
    Abstract: The aim of the study was to investigate the underlying cause of long-term complications in patients requiring at least one revision surgery of a continent ileostomy (CI) and to analyze functional outcome. Methods Only patients with CI at least one revision were included in the retrospective data analysis. Four different classes of complications (Cl A–D) were defined: Cl A = Nipple valve (NV), Cl B = pouch, Cl C = outlet (stoma), and Cl D = afferent loop (AL). Associations between underlying disease and origin of complications were analyzed. Cumulative probabilities were calculated using Kaplan–Meier analysis. Results A total of 77 patients were identified with a follow-up of 30 years, requiring 133 surgeries for 148 complications (c.). Cl A 49 c. (33.1%), Cl B 50 c. (33.8%), Cl C 39 c. (26.4%), and Cl D 10 c. (6.8%). Cl A and C complications were not correlated to underlying disease, whereas Cl B and D complications were only found in ulcerative colitis (UC) and Crohn’s disease (CD). The cumulative probability of a second revision showed a linear rise, reaching 62.5% after 20 years. Cl A and B complications both reached 42.1%. Eleven (14.3%) patients (10 Cl B) had pouch failure in a follow-up period of 11.5 ± 8.7 years (1–31 years), whereas 66 (85.7%) had successful revisional surgery. Overall CI survival was 78.8% at 44 years. Conclusion CI survival is limited by inflammatory complications of the pouch based on the underlying disease and not by mechanical limitations of the NV. Trial registration numbers None.
    Type of Medium: Online Resource
    ISSN: 0179-1958 , 1432-1262
    RVK:
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1459217-4
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  • 5
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2021
    In:  BJS Open Vol. 5, No. 5 ( 2021-09-06)
    In: BJS Open, Oxford University Press (OUP), Vol. 5, No. 5 ( 2021-09-06)
    Abstract: Continent ileostomy (CI) aims to provide control of gas and faecal evacuation; however, it is rarely performed. This paper reports on outcomes of CI in a large single-surgeon series. Methods All consecutive patients who underwent CI between 1986 and 2015 were reviewed. Patients were classified according to the CI procedure (single stage versus two stage) and according to the underlying disease conditions (inflammatory bowel disease (IBD) versus no IBD). Primary outcome measures were early mortality and complications requiring surgical revision within 30 days (group Ia), those requiring surgical revision within 1–12 months (group Ib), and long-term complications after more than 12 months (group II). Secondary outcome measures were pouch survival and quality of life (QoL) assessed using questionnaires for occupational, sports, sexual, and travel activities; patients undergoing CI after conversion from ileostomy. Analyses were performed using descriptive statistics and Kaplan–Meier curves for the long-term outcomes. Results Sixty-two consecutive patients (28 men, 34 women) who underwent CI were reviewed, including 48 with IBD, and 14 without inflammatory conditions. Mean(s.d.) follow-up was 14.4 (9.5) (range 1–30) years. Twenty-seven patients (44 per cent) developed group I complications, of which 25 were corrected successfully. Two patients dropped out of the analysis: one who died from sepsis and the other owing to pouch loss attributed to unsolvable nipple complications. Of the remaining 60 patients, 23 (38 per cent) developed between one and five group II complications. The cumulative probability of reoperation was 54. per cent at 25 years. Overall, pouch survival was achieved in 90 per cent. The two-stage approach led to significantly fewer complications in group Ia (single stage versus two stage: 8 of 25 versus 2 of 37; P = 0.005), whereas complication rates in group Ib (5 of 23 versus 14 of 37) and group II (9 of 23 versus 14 of 37) were similar. Four CIs failed because of IBD complications. CI pouch and function were preserved in all patients without IBD, whereas in the group with IBD 2 of 31 with ulcerative colitis and 2 of 17 with Crohn’s colitis lost the CI owing to severe intractable inflammatory complications. In 16 patients who had conversion from ileostomy to CI, QoL improved significantly above precolectomy levels in all domains Conclusions CI remains an alternative to conventional ileostomy. Although affected by high reoperation rates, it has the benefit of a high rate of pouch survival.
    Type of Medium: Online Resource
    ISSN: 2474-9842
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2902033-5
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  • 6
    In: Colorectal Disease, Wiley, Vol. 24, No. 5 ( 2022-05), p. 631-638
    Abstract: The aim was to evaluate surgical strategies for conversion of failed ileo‐pouch anal anastomosis (IPAA) to continent ileostomy (CI), taking morbidity and overall outcome into account. The hypothesis was that complex conversions are equivalent to the primary construction of a CI at the time of proctocolectomy. Method This was a retrospective analysis of IPAA conversions acknowledging the underlying disease (inflammatory bowel disease [IBD] and non‐IBD) and extent of pouch reconstruction (PR): type 1 (without PR), type 2 (partial PR), and type 3 (complete PR). Results Twenty‐six patients (IBD, n  = 16; non‐IBD, n  = 10) were converted (type 1, n  = 13; type 2, n  = 7; and type 3, n  = 6).12/26 patients (46.2%) presented postoperative complications directly related to the conversion with scarification of two pouches. In a mean follow‐up time of 7.5 ± 6.6 years, 5/24 patients required revisional surgery. Of these, three required pouch excision. The cumulative probability of reoperation at the end of the second year increased to 21.7% and remained constant thereafter until the maximum follow‐up time of 26 years. The total pouch loss rate was 19.2% (5/26), of which all occurred in the first 3 years. No statistically significant differences were found between the conversion types, complications or pouch survival. For all parameters, IBD patients performed slightly unfavourably. Due to the overall small number of respective patients, a differentiated investigation of IBD was not performed. Conclusion Complex conversion procedures (types 1 and 2) deliver comparable long‐term results to new constructions (type 3), thereby limiting the loss of small bowel. IBD compromises outcome versus non‐IBD.
    Type of Medium: Online Resource
    ISSN: 1462-8910 , 1463-1318
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2004820-8
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  • 7
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2008
    In:  European Journal of Trauma and Emergency Surgery Vol. 34, No. 3 ( 2008-6), p. 219-228
    In: European Journal of Trauma and Emergency Surgery, Springer Science and Business Media LLC, Vol. 34, No. 3 ( 2008-6), p. 219-228
    Type of Medium: Online Resource
    ISSN: 1863-9933 , 1863-9941
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2008
    detail.hit.zdb_id: 2276432-X
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  • 8
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 1999
    In:  Diseases of the Colon & Rectum Vol. 42, No. 10 ( 1999-10), p. 1311-1317
    In: Diseases of the Colon & Rectum, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 10 ( 1999-10), p. 1311-1317
    Type of Medium: Online Resource
    ISSN: 0012-3706
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 1999
    detail.hit.zdb_id: 2046914-7
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  • 9
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 1999
    In:  European Journal of Gastroenterology & Hepatology Vol. 11, No. 3 ( 1999-03), p. 277-282
    In: European Journal of Gastroenterology & Hepatology, Ovid Technologies (Wolters Kluwer Health), Vol. 11, No. 3 ( 1999-03), p. 277-282
    Type of Medium: Online Resource
    ISSN: 0954-691X
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 1999
    detail.hit.zdb_id: 2030291-5
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  • 10
    Online Resource
    Online Resource
    Elsevier BV ; 1989
    In:  Baillière's Clinical Gastroenterology Vol. 3, No. 3 ( 1989-7), p. 531-541
    In: Baillière's Clinical Gastroenterology, Elsevier BV, Vol. 3, No. 3 ( 1989-7), p. 531-541
    Type of Medium: Online Resource
    ISSN: 0950-3528
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1989
    detail.hit.zdb_id: 2151812-9
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