In:
Molecular and Cellular Biology, Informa UK Limited, Vol. 10, No. 9 ( 1990-09), p. 4957-4960
Abstract:
Methylated DNA-binding protein (MDBP), a sequence-specific DNA-binding protein, was found to recognize more than 30 sites within an allele of the human apolipoprotein(a) gene. High plasma levels of apolipoprotein(a), a risk factor for atherosclerosis, have been correlated with genetically inherited lower-molecular-mass isoforms of this protein. MDBP might help down modulate the expression of the apolipoprotein(a) gene in a manner dependent on the length of a given allele of the gene and the number of MDBP sites in it.
Type of Medium:
Online Resource
ISSN:
0270-7306
,
1098-5549
DOI:
10.1128/MCB.10.9.4957
Language:
English
Publisher:
Informa UK Limited
Publication Date:
1990
detail.hit.zdb_id:
1474919-1
SSG:
12
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