In:
Journal of International Medical Research, SAGE Publications, Vol. 42, No. 5 ( 2014-10), p. 1168-1177
Abstract:
To examine retrospectively the relationship between acute kidney injury (AKI) and acute myocardial infarction (AMI), and the association between estimated glomerular filtration rate (eGFR) at admission and AKI outcome. Methods AKI was defined as an increase in serum creatinine (SCr) by ≥0.3 mg/dl within 48 h or an increase in SCr to ≥1.5 times baseline within the first 7 days of hospitalization. Patients with AMI were divided into subgroups according to their eGFR at admission and the development of AKI. Results This study enrolled 396 patients with AMI; 48 (12.1%) developed AKI. In-hospital mortality was 39.6% (19/48) for patients with AKI compared with 7.5% (26/348) in those without AKI (odds ratio [OR] 8.11; 95% confidence interval [CI] 4.02, 16.39). The mortality rate was 35.7% (five of 14) in the eGFR ≥ 60 ml/min/1.73m 2 with AKI group (OR 6.21, 95% CI 1.50, 25.69) and 41.2% (14/34) in the eGFR 〈 60 ml/min/1.73m 2 with AKI group (OR 12.62, 95% CI 5.54, 28.74). Conclusions AKI development was common and associated with mortality in AMI patients with either preserved or impaired eGFR levels.
Type of Medium:
Online Resource
ISSN:
0300-0605
,
1473-2300
DOI:
10.1177/0300060514541254
Language:
English
Publisher:
SAGE Publications
Publication Date:
2014
detail.hit.zdb_id:
2082422-1
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