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A second update on mapping the human genetic architecture of COVID-19

The COVID-19 Host Genetics Initiative ; Kanai, Masahiro ; Andrews, Shea J. ; [et al.]

Springer Science and Business Media LLC ; 2023

In: Nature Vol. 621, No. 7977 ( 2023-09-07), p. E7-E26

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In: Nature, Springer Science and Business Media LLC, Vol. 621, No. 7977 ( 2023-09-07), p. E7-E26

Type of Medium: Online Resource

ISSN: 0028-0836 , 1476-4687

URL: Article

DOI: 10.1038/s41586-023-06355-3

RVK:

TA 1000

RVK:

UA 1000

RVK:

WA 15000

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2023

detail.hit.zdb_id: 120714-3

detail.hit.zdb_id: 1413423-8

SSG: 11

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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, Gabriëlla A.M. ; Grove, Jakob ; Chen, Chia-Yen ; [et al.]

Elsevier BV ; 2022

In: Biological Psychiatry Vol. 91, No. 1 ( 2022-01), p. 102-117

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In: Biological Psychiatry, Elsevier BV, Vol. 91, No. 1 ( 2022-01), p. 102-117

Type of Medium: Online Resource

ISSN: 0006-3223

URL: Article

DOI: 10.1016/j.biopsych.2021.02.972

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2022

detail.hit.zdb_id: 1499907-9

SSG: 12

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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Ruderfer, Douglas M. ; Ripke, Stephan ; McQuillin, Andrew ; [et al.]

Elsevier BV ; 2018

In: Cell Vol. 173, No. 7 ( 2018-06), p. 1705-1715.e16

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In: Cell, Elsevier BV, Vol. 173, No. 7 ( 2018-06), p. 1705-1715.e16

Type of Medium: Online Resource

ISSN: 0092-8674

URL: Article

DOI: 10.1016/j.cell.2018.05.046

RVK:

XA 36269

RVK:

WA 15000

Language: English

Publisher: Elsevier BV

Publication Date: 2018

detail.hit.zdb_id: 187009-9

detail.hit.zdb_id: 2001951-8

SSG: 12

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Relationship Between Liver Biochemical Tests and Dietary Intake in Patients with Liver Disease

Deems, Rhonda Oetting ; Friedman, Lawrence S. ; Friedman, Mark I. ; [et al.]

Ovid Technologies (Wolters Kluwer Health) ; 1994

In: Journal of Clinical Gastroenterology Vol. 18, No. 4 ( 1994-06), p. 304-308

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In: Journal of Clinical Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 18, No. 4 ( 1994-06), p. 304-308

Type of Medium: Online Resource

ISSN: 0192-0790

URL: Article

DOI: 10.1097/00004836-199406000-00009

Language: English

Publisher: Ovid Technologies (Wolters Kluwer Health)

Publication Date: 1994

detail.hit.zdb_id: 2041558-8

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Limonene in expired lung air of patients with liver disease

Friedman, Mark I. ; Preti, George ; Deems, Rhonda O. ; [et al.]

Springer Science and Business Media LLC ; 1994

In: Digestive Diseases and Sciences Vol. 39, No. 8 ( 1994-8), p. 1672-1676

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In: Digestive Diseases and Sciences, Springer Science and Business Media LLC, Vol. 39, No. 8 ( 1994-8), p. 1672-1676

Type of Medium: Online Resource

ISSN: 0163-2116 , 1573-2568

URL: Article

DOI: 10.1007/BF02087774

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 1994

detail.hit.zdb_id: 2015102-0

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Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

Gaudet, Mia M. ; Kirchhoff, Tomas ; Green, Todd ; [et al.]

Public Library of Science (PLoS) ; 2010

In: PLoS Genetics Vol. 6, No. 10 ( 2010-10-28), p. e1001183-

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In: PLoS Genetics, Public Library of Science (PLoS), Vol. 6, No. 10 ( 2010-10-28), p. e1001183-

Type of Medium: Online Resource

ISSN: 1553-7404

URL: Article

DOI: 10.1371/journal.pgen.1001183

DOI: 10.1371/journal.pgen.1001183.g001

DOI: 10.1371/journal.pgen.1001183.t001

DOI: 10.1371/journal.pgen.1001183.t002

DOI: 10.1371/journal.pgen.1001183.s001

DOI: 10.1371/journal.pgen.1001183.s002

DOI: 10.1371/journal.pgen.1001183.s003

DOI: 10.1371/journal.pgen.1001183.s004

DOI: 10.1371/journal.pgen.1001183.s005

DOI: 10.1371/journal.pgen.1001183.s006

DOI: 10.1371/journal.pgen.1001183.s007

DOI: 10.1371/journal.pgen.1001183.s008

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2010

detail.hit.zdb_id: 2186725-2

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Chemosensory Function, Food Preferences and Appetite in Human Liver Disease

Deems, Rhonda Oetting ; Friedman, Mark I. ; Friedman, Lawrence S. ; [et al.]

Elsevier BV ; 1993

In: Appetite Vol. 20, No. 3 ( 1993-6), p. 209-216

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In: Appetite, Elsevier BV, Vol. 20, No. 3 ( 1993-6), p. 209-216

Type of Medium: Online Resource

ISSN: 0195-6663

URL: Article

DOI: 10.1006/appe.1993.1021

Language: English

Publisher: Elsevier BV

Publication Date: 1993

detail.hit.zdb_id: 1461347-5

SSG: 12

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Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial

Menon, Bijoy K ; Buck, Brian H ; Singh, Nishita ; [et al.]

Elsevier BV ; 2022

In: The Lancet Vol. 400, No. 10347 ( 2022-07), p. 161-169

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In: The Lancet, Elsevier BV, Vol. 400, No. 10347 ( 2022-07), p. 161-169

Type of Medium: Online Resource

ISSN: 0140-6736

URL: Article

DOI: 10.1016/S0140-6736(22)01054-6

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2022

detail.hit.zdb_id: 2067452-1

detail.hit.zdb_id: 3306-6

detail.hit.zdb_id: 1476593-7

SSG: 5,21

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Trapped fat: Obesity pathogenesis as an intrinsic disorder in metabolic fuel partitioning

Friedman, Mark I. ; Sørensen, Thorkild I. A. ; Taubes, Gary ; [et al.]

Wiley ; 2024

In: Obesity Reviews

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In: Obesity Reviews, Wiley

Abstract: Our understanding of the pathophysiology of obesity remains at best incomplete despite a century of research. During this time, two alternative perspectives have helped shape thinking about the etiology of the disorder. The currently prevailing view holds that excessive fat accumulation results because energy intake exceeds energy expenditure, with excessive food consumption being the primary cause of the imbalance. The other perspective attributes the initiating cause of obesity to intrinsic metabolic defects that shift fuel partitioning from pathways for mobilization and oxidation to those for synthesis and storage. The resulting reduction in fuel oxidation and trapping of energy in adipose tissue drives a compensatory increase in energy intake and, under some conditions, a decrease in expenditure. This theory of obesity pathogenesis has historically garnered relatively less attention despite its pedigree. Here, we present an updated comprehensive formulation of the fuel partitioning theory, focused on evidence gathered over the last 80 years from major animal models of obesity showing a redirection of fuel fluxes from oxidation to storage and accumulation of excess body fat with energy intake equal to or even less than that of lean animals. The aim is to inform current discussions about the etiology of obesity and by so doing, help lay new foundations for the design of more efficacious approaches to obesity research, treatment and prevention.

Type of Medium: Online Resource

ISSN: 1467-7881 , 1467-789X

URL: Article

DOI: 10.1111/obr.13795

Language: English

Publisher: Wiley

Publication Date: 2024

detail.hit.zdb_id: 2020497-8

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Drinking saccharin increases food intake and preference—I. Comparison with other drinks

Tordoff, Michael G. ; Friedman, Mark I.

Elsevier BV ; 1989

In: Appetite Vol. 12, No. 1 ( 1989-2), p. 1-10

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In: Appetite, Elsevier BV, Vol. 12, No. 1 ( 1989-2), p. 1-10

Type of Medium: Online Resource

ISSN: 0195-6663

URL: Article

DOI: 10.1016/0195-6663(89)90064-0

Language: English

Publisher: Elsevier BV

Publication Date: 1989

detail.hit.zdb_id: 1461347-5

SSG: 12

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