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  • 1
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 28_suppl ( 2022-10-01), p. 11-11
    Abstract: 11 Background: The Oncology Care Model (OCM), a 6-year long Medicare value-based care program, rewards practices for decreasing total cost of care (TCOC) compared to a benchmark price, while maintaining high quality cancer care. Care services for enrolled patients are divided into 6-month episodes within 1-year time intervals called Performance Periods (PP). One approach to reducing TCOC is reducing the expenditure for drug waste. In mid-2017, trastuzumab (HER2-targeted monoclonal antibody) 420 mg multi-dose vial (MDV) was discontinued and replaced with a 150 mg single-dose vial (SDV), leading to wastage of the remaining partial quantities of the SDV after preparation of a patient-defined dose. The increased drug waste led to an increase in the total drug cost of trastuzumab and TCOC. Late 2019, MDV and SDV biosimilar trastuzumab products were introduced, and The US Oncology Network (The Network) practices adopted the MDV biosimilar as a strategy to reduce drug waste and TCOC. This study highlights the impact of trastuzumab drug waste on TCOC. Methods: Claims data for 14 Network practices, participating in OCM, were assessed. The financial impact of drug waste and TCOC for The Network’s transition from MDV trastuzumab to SDV trastuzumab in 2017, and from SDV trastuzumab to the MDV biosimilar trastuzumab in 2020 was evaluated. Results: With the use of MDV trastuzumab during OCM PP1, drug waste accounted for 0.05% of the total dose of trastuzumab. After having to shift from MDV to SDV during PP2, as a result of the packaging change, trastuzumab drug waste increased to 10.25% of the total dose, with an increase in TCOC by 0.25% ($2M) per PP during PPs 3-7. As The Network practices adopted the use of MDV biosimilar trastuzumab starting in PP8, drug waste declined 57% to 4.4% of the total dose in PP9, reducing the drug waste component of TCOC by $1.4M (0.16%). Had all SDV trastuzumab doses been transitioned to the MDV biosimilar, an additional $600K (0.09%) in TCOC could have been reduced in PP9. Conclusions: TCOC fluctuations can be driven by not just increasing costs or increased utilization, but also by drug packaging and increasing drug waste. The discontinuation of MDV trastuzumab resulted in a substantial financial impact on drug waste, TCOC, and cost for patients. Swift transition to biosimilar MDV trastuzumab within The Network helped to significantly reduce drug waste and its impact on TCOC in the OCM. Trastuzumab biosimilars, in addition to being cost-effective alternatives to biological therapeutics, offer significant cost savings via drug waste reduction.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
    detail.hit.zdb_id: 2005181-5
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  • 2
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    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2019
    In:  Journal of Clinical Oncology Vol. 37, No. 15_suppl ( 2019-05-20), p. 6636-6636
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 37, No. 15_suppl ( 2019-05-20), p. 6636-6636
    Abstract: 6636 Background: Febrile neutropenia (FN) resulting from myelosuppressive chemotherapy can lead to increased hospitalizations and mortality. Pegfilgrastim can be used to reduce the risk of FN; however, few studies address pegfilgrastim’s value in patients with metastatic solid tumors. This observational study compared outcomes for pegfilgrastim-treated (peg-tx) and peg-untreated (no peg) patients with metastatic colorectal (CRC) at US Oncology practices (USO) participating in the Oncology Care Model. Methods: Patients with metastatic CRC treated at USO from July 1, 2013 – December 31, 2014 and a qualifying baseline OCM episode were included. Propensity scoring was used to match (1:2) peg-tx and no peg cohorts based on line of therapy, number of comorbidities, age, gender, ECOG performance status, chemotherapy neutropenic fever risk, and dose reduction. Outcomes assessed included all-cause and infection-related hospitalization rates; total cost of care per 6-month OCM episode; and overall survival (OS). Results: Matched peg-tx and no peg samples were 149:298. The all-cause hospitalization rate was higher in the peg-tx vs. no peg population, 45% vs. 32% (OR 1.7, (1.1, 2.5), p = 0.011). Infection-related hospitalization rates were no different in peg-tx vs. no peg cohorts, p = 0.367. Cost of care was significantly higher for peg-tx patients vs. no peg ($58,787 ± $20,490 vs. $37,811 ± $19,593 respectively, p 〈 .001). OS was 19.5 months (peg-tx) vs. 19.7 months (no peg), p = 0.882. Conclusions: While peg use in curative treatment settings for high risk patients is standard of care, in our Medicare population use in metastatic CRC did not result in a lower all-cause or infection-related hospitalization rate or impact in OS. There was a higher 6-month total cost of care associated with those patients who received peg during chemotherapy.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2019
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  • 3
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. e17019-e17019
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. e17019-e17019
    Abstract: e17019 Background: Therapeutic interchange (TIC) to lower-cost generic products offers significant cost savings to payers and patients while maintaining equivalent quality of care. The Oncology Care Model (OCM) is a value-based care program from Medicare that rewards practices for decreasing the total cost of care (TCOC) compared to historical baseline prices that are adjusted by a trend factor to account for rising cost trends in oncology. One strategy for bending the cost curve is to utilize lower cost medications. A generic version of abiraterone acetate (FDA approved for treatment of Prostate Cancer) was first introduced into the market in late 2018. This led to a concerted approach to interchange the brand product with the generic equivalent in The US Oncology Network (The Network) as an opportunity to reduce TCOC. Here we describe utilization and the financial impact of abiraterone TIC in The Network during OCM performance period 8 (PP8) which enrolled patients from 1/2/2020 to 7/1/2020. Methods: Prescription drugs dispense data for the 14 US Oncology Network practices participating in the OCM were used to determine brand and generic abiraterone utilization. The impact of TIC on TCOC was measured by comparing the cost of the generic product vs. the estimated cost of the brand agents. Results: TIC resulted in an increase in generic abiraterone use from prior performance periods. Generic abiraterone increased from 0% in PP4 to 24% in PP5, 55% in PP6, 67% in PP7 and 80% in PP8 within the Network. We compared the actual cost of all abiraterone dispenses in PP8 vs. the calculated cost (based on Average Wholesale Price less 17.5%) of the brand product if the more expensive brand drugs were used instead. The difference in the actual cost vs estimated cost led to a savings of $4.37 million in PP6, $6.34 million in PP7 and $9.37 million in PP8 (about 1% of TCOC) by using generic versus brand abiraterone alone. Conclusions: TIC from brand to generic abiraterone in The Network generated significant savings for OCM. Continued shift towards lower cost generics will increase savings to CMS in the Oncology Care Model. We estimate that 100% Network adoption of the generic abiraterone could save nearly 1.25% of the TCOC compared to continued use of brand product.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
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  • 4
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    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2018
    In:  Journal of Clinical Oncology Vol. 36, No. 30_suppl ( 2018-10-20), p. 33-33
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 36, No. 30_suppl ( 2018-10-20), p. 33-33
    Abstract: 33 Background: Texas Oncology (TO) is a community-based practice. with over 250 physicians (MD) who order chemotherapy. In 2015, pegfilgrastim (pgcsf) was the highest individual drug in billed claims. Concurrently, TO was participating in the United Healthcare (UHC) Episode of Care (EOC) program and anticipating the Oncology Care Model. Patient and program expense dictated understanding pgcsf utilization. Methods: Data were obtained in 9/2015 from EOC claims to identify overall and individual pgcsf use in solid tumor metastatic disease (MDx). Chart review was done for the top prescribers. In 3/16, ASCO pgcsf guidelines and TO education materials were emailed to all physicians. In 3/17 appropriate non-use recommendations were communicated and a real-time internal approval process begun. On 10/1/2017, UHC instituted a pgcsf prior authorization (PA) program. Retrospective data from the iKnowMed EHR system was collected in 3-month intervals from April 2016 through March 2018 and evaluated for number of pgcsf administrations at TO for MDx, as well as, administrations/provider/quarter for TO and The US Oncology Network. MDx was defined by any of the following criteria: stage IV at diagnosis (with certain disease exceptions); TNM M value of “1” or “+”; a metastatic line of therapy; evidence of metastatic disease documented within the EHR. Results: Initial survey of EOC claims indicated 16% of patients received pgcsf for MDx. Rates per MD ranged from 0 to 57%. Review of the top users indicated 90% of uses could have been addressed with dose reduction. In the first measured quarter of April to June 2016 to the last, October to December 2017, pgcsf use dropped by 50%. Changes for some diseases were dramatic: Use in colon cancer fell from 132 uses/quarter to a low of 46, and for non-small lung cancer – 80 to 23 respectively. Conclusions: The deadopting of low value care can be challenging. In the case of pgcsf substantial reductions in use were achieved using data and guidelines for education in the setting of value based contracts. Ultimately, the most change was achieved by an internal real time approval process. This was reinforced by a payer PA requirement.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2018
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  • 5
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    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2021
    In:  Journal of Clinical Oncology Vol. 39, No. 15_suppl ( 2021-05-20), p. 6514-6514
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 39, No. 15_suppl ( 2021-05-20), p. 6514-6514
    Abstract: 6514 Background: The emergence of biosimilars creates an opportunity for more cost-effective treatment. Utilization of biologics in cancer care has increased and accounts for 70% of oncologic drug spending growth from 2010 to 2015. Biosimilars can play a vital role in controlling this rapid rise in cost. Practices focused on Value Based Care arrangements, such as the Oncology Care Model, can reduce total cost of care by increasing utilization of biosimilars. The process of interchange is complicated by the designation of each biosimilar which prevents simple interchange. Communication with physicians and the healthcare team along with patient education and consent must be performed. We describe a successful model for therapeutic interchange of brand drugs to biosimilars. Methods: Texas Oncology elected to increase utilization of biosimilars in 2020. We collaborated with McKesson Specialty Health to create educational materials for patients and clinical staff. Communication was sent to all personnel about the therapeutic interchange process. A central pharmacy team reviewed all new orders and substituted a biosimilar for brand, unless a payer insisted on origin drug or a biosimilar not in the practice formulary. Additionally, a report was generated weekly of all existing patients who would benefit from switching. The pharmacists, upon consultation with the physician, then substituted a biosimilar for brand drug. Patients were then educated and re-consented. We started with rituximab in 07/2020 followed by bevacizumab in 09/2020 then trastuzumab in 10/2020. Results: The table below shows our conversion rate for all administrations. We were able to increase utilization of biosimilars from January of 2020 to December of 2020 from 5% to 80% for Rituximab, 9% to 88% for bevacizumab and 8% to 74% for trastuzumab. Based on average ASP for a 70 kg patient, the potential savings per administration is $550 for bevacizumab, $850 for trastuzumab, and $1400 for rituximab. In one month alone, this project dramatically reduced cost by $4 million or 21% by conversion to these three biosimilars. Additional savings can be realized with the use of biosimilar multi-dose vials vs single dose vials. Conclusions: Our comprehensive team approach successfully deploys therapeutic interchange of biosimilars for brand drugs in a community oncology practice which leads to substantial cost savings. This has real implications in controlling the total cost of care.[Table: see text]
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2021
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  • 6
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 28_suppl ( 2022-10-01), p. 5-5
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 28_suppl ( 2022-10-01), p. 5-5
    Abstract: 5 Background: The Oncology Care Model (OCM) is a Medicare value-based care program, that rewards practices for decreasing the total cost of care (TCOC) compared to a benchmark price. Enrolled patients are evaluated in 6-month episodes within a 1-year time window called Performance Periods (PP). The use of lower cost medication alternatives (LCA) is a critical strategy to bend the cost curve. Therapeutic interchange (TIC) with lower-cost generic/biosimilar/therapeutic alternative medications offer significant cost savings to payers and patients while maintaining equivalent quality of care. LCA for eight high-cost oncology therapeutic or supportive care medications became available during or just prior to OCM. The results of a clinically appropriate, physician-supported, pharmacist-led interchange of high-cost medications to LCA in The US Oncology Network (The Network) during OCM PP 7 (PP7), 8 (PP8), and 9 (PP9) is described here. Methods: Medicare Part B & D claims for 14 OCM practices in The Network were used to evaluate the impact of eight TIC opportunities during PP 7-9. TIC opportunities included changing therapy from reference products to biosimilars (bevacizumab, trastuzumab, rituximab, pegfilgrastim and filgrastim), from brand to generics (abiraterone, imatinib, fosaprepitant) and from high cost to LCA (aprepitant to fosaprepitant, denosumab to zoledronic acid). TCOC impact was measured by comparing the cost of each dose of the LCA vs the estimated cost if the more expensive alternative had been used instead. Results: The shift from high cost to LCAs in PP7, PP8 and PP9 is shown in Table as percentage of total doses dispensed or administered. Transitions from aprepitant to fosaprepitant, and from denosumab to zoledronic acid was done when clinically appropriate (as determined by the treating physician). The cumulative savings from TIC was $26.0M in PP7, $32.3M in PP8 and $32.9M in PP9. TIC to biosimilars contributed $6.6M in PP8 and $12.2M in PP9 of the cumulative savings. TIC reduced TCOC by 2.78% in PP7, 4.13% in PP8, 5.25% in PP9 within the OCM. Conclusions: TIC to biosimilars, generics and clinically appropriate LCA is an effective way to reduce TCOC while maintaining quality care in the OCM. Even small shifts in utilization towards LCA can generate a significant reduction in TCOC. Physician-supported, pharmacist-led TIC initiatives are critical to bending the cost curve within Oncology.[Table: see text]
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    RVK:
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
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  • 7
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. e18749-e18749
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. e18749-e18749
    Abstract: e18749 Background: Biosimilar adoption offers the potential to save significant cost while maintaining high quality of care. The Oncology Care Model (OCM) is structured to reward practices for decreasing total cost of care (TCOC) compared to historical baseline prices that are adjusted by a trend factor accounting for the rising cost of oncology care. Practices are rewarded for bending the cost curve by utilizing lower cost medications. Biosimilar options were introduced for 3 mainstay therapeutic classes in oncology, bevacizumab and trastuzumab in 2019, and rituximab in 2020. This led to a concerted approach for biosimilar adoption in The US Oncology Network (The Network) as an opportunity to reduce TCOC. Here we describe utilization and the financial impact of biosimilar adoption in The Network during OCM performance period 8 (PP8) which enrolled patients from 1/2/2020 to 7/1/2020. Methods: Claims data for the 14 US Oncology Network practices participating in the OCM were used to determine biosimilar utilization for bevacizumab, trastuzumab, and rituximab therapeutic classes. The impact of biosimilar utilization on TCOC was measured by comparing the cost of each dose of a biosimilar vs the estimated cost if the more expensive innovator agent had been used instead. Results: Biosimilar utilization increased for each therapeutic class from prior performance periods. Biosimilar use for bevacizumab was 0% in PP6, 5% in PP7 and 43% in PP8. For trastuzumab, utilization was 0% in PP6, 4% in PP7 and 33% in PP8. Rituximab biosimilar utilization was 0% in PP6, 2% in PP7 and 41% in PP8. We compared the actual cost of these three medications in our OCM claims in PP8 vs. the calculated cost based on Medicare reimbursement as ASP + 6% minus sequestration if the more expensive innovator drugs had been used entirely. The difference in the actual cost vs estimated cost led to a savings of $6.61 million by using the biosimilars over innovator drugs. Conclusions: The increased utilization of biosimilars in The Network generated significant savings in OCM. Continued adoption of biosimilars will increase savings to Medicare in the Oncology Care Model. We estimate that 100% Network adoption of these three biosimilars could save nearly 1.5% of the TCOC in our Network compared to continued use of innovator drugs.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    RVK:
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
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  • 8
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 28_suppl ( 2022-10-01), p. 12-12
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 28_suppl ( 2022-10-01), p. 12-12
    Abstract: 12 Background: The Oncology Care Model (OCM) is an episode-based, Medicare value-based care program, that rewards providers for decreasing the total cost of care (TCOC) compared to a benchmark price. The model differentiates breast & prostate cancer treated with hormone-only therapy, and bladder cancer treated with Bacillus Calmette-Guérin and/or mitomycin as low-risk episodes (LRE). All other qualifying cancers, including breast, prostate & bladder cancer treated with chemotherapy are designated as high-risk episodes (HRE). Independent evaluation of OCM Performance Periods (PP) 1-6 suggests that reductions in TCOC predominantly occurred in HRE but were offset by increased TCOC in LRE. We seek to evaluate the episode characteristics that have a bearing on LRE performance in OCM. Methods: Episode claims data for 14 practices in The US Oncology Network (The Network) participating in OCM during PP 1-6 were assessed. Several episode characteristics including patient age, gender, comorbidities, cancer type, oncology touchpoints, etc. were evaluated. Results: LRE accounted for 30.5% of total episodes for The Network in OCM from PP1-6, with average benchmark price of $6,700. 85% of LRE were breast cancer patients with average benchmark of $5,800. Only 30% of LRE had increased TCOC exceeding benchmark. Average TCOC increased gradually with increasing age, with highest TCOC at extremes of patient age (18-64 and 80+). Episodes with multiple comorbidities (defined as Hierarchical Condition Category (HCC) flags 3, 4-5, 6+) had an average TCOC 3-times higher than episodes with fewer-or-no comorbidities (HCC flags 0, 1, 2). Episode expenses beyond cancer care (inpatient, nursing facility, home health, long term care, durable medical equipment, and inpatient rehabilitation) were 2.5 times higher for patients with advancing age (75-79 or 80+) and multiple comorbidities. Additionally, these patients had lower physician services expenses, fewer oncology care touchpoints (defined as visits with the Oncology practice), and a four-fold higher death rate. Conclusions: In the OCM, LRE for older patients with multiple comorbidities had higher TCOC, with fewer oncology touchpoints, higher death rates, and episode expenses beyond cancer care contributing the most to TCOC. Incorporating a comprehensive geriatric assessment (composed of physical, functional, cognitive, mental, and socioenvironmental factors) could guide oncologic therapeutic choices, and appropriate clinical management of these patients to improve outcomes. In addition, a modified, resource utilization-based risk adjustment approach could better fit this population.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
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  • 9
    Online Resource
    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2023
    In:  Journal of Clinical Oncology Vol. 41, No. 16_suppl ( 2023-06-01), p. 1529-1529
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 41, No. 16_suppl ( 2023-06-01), p. 1529-1529
    Abstract: 1529 Background: The Oncology Care Model (OCM) was a 6-year long Medicare value-based care (VBC) program that rewarded practices for decreasing TCOC compared to a benchmark price, while maintaining high-quality cancer care. Drug waste from partially used single dose vials (SDV) of expensive anti-neoplastic agents is a leading contributor to avoidable Total Cost of Care (TCOC) expenditures for payers. Dose rounding (DR) of biological anti-neoplastic agents, using recommendations (https://www.nccn.org/docs/default-source/clinical/order-templates/hopa.pdf?sfvrsn=3af91118_6) from the Hematology Oncology Pharmacists Association (HOPA) and endorsed by the National Comprehensive Cancer Network (NCCN), is a standard approach to mitigate the impact of drug waste. Many of the practices in The US Oncology Network (The Network) adopted a DR program for biologic agents in 2018 as a strategy to reduce drug waste and TCOC. We studied the impact of a DR initiative targeting bevacizumab and its biosimilars (B+B) on TCOC and drug waste expenditures for The Network practices participating in the OCM. Methods: Claims data for 14 practices in The Network participating in the OCM were assessed. Drug administration data for B+B was used to evaluate drug waste, total dose, TCOC, DR and the financial impact of drug waste reduction on TCOC from 2017 to 2021. Results: In 2017, prior to implementing DR, an average of 5.3% (range 4.6% to 5.5%) of the total dose of B+B was wasted, with ~25% of B+B administrations having waste in excess of 10% of the total dose. Implementation of the initiative led to a reduction of waste on 30% of the total administrations of B+B across 14 OCM participant practices in The Network. As a result of DR, B+B drug waste decreased by 55% to an average of 2.5% (range - 2.3% to 2.7%) of the total dose in 2021. Decreasing drug waste resulted in TCOC reduction of approximately $100 per member episode per month (0.97% of TCOC) for episodes with B+B administrations in the OCM. The highest waste reduction was seen with B+B administered for treatment of gastrointestinal cancers (colon, rectal, anal, gastroesophageal, or pancreatic cancers) compared to other cancer types (lung, brain, ovarian, etc.), and for B+B administrations where drug waste was greater than 10% of the total dose (~50% reduction). Conclusions: Drug waste contributes avoidable expenditures to the TCOC. Implementing strategies such as DR can offset the impact of drug waste and offer meaningful TCOC savings for VBC programs such as the OCM. A similar DR approach may be adopted for other high-cost biologic agents where drug waste results from partial use of SDVs.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2023
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  • 10
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    Online Resource
    American Society of Clinical Oncology (ASCO) ; 2023
    In:  Journal of Clinical Oncology Vol. 41, No. 16_suppl ( 2023-06-01), p. 6651-6651
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 41, No. 16_suppl ( 2023-06-01), p. 6651-6651
    Abstract: 6651 Background: The Oncology Care Model (OCM) was a value-based care program implemented by the Centers for Medicare & Medicaid Innovation (CMMI) between July 1, 2016, and June 30, 2022, that aimed to provide high-quality care while reducing total cost of care (TCOC). In 2023 CMS plans to implement the Enhancing Oncology Model (EOM), which builds on lessons learned from the OCM. Over 200 novel therapies were approved by the FDA between 2016 and 2022. Novel therapies come with increased cost, leading to concerns that the model could discourage use of novel therapies. CMMI implemented a novel therapy adjustment (NTA) to offset the increased cost of these expensive therapies, when a practice has a higher proportion of novel therapy expenditures. A key change in the EOM is the calculation for NTA at the individual cancer type level compared to full population of episodes in the OCM. We studied the impact of moving from a population-based NTA to a cancer type-based NTA calculation. Methods: Claims and performance data from 10 performance periods (PP) in the OCM (PP1 to PP10) for 14 practices in The US Oncology Network were reviewed. Descriptive statistics for the simulation were evaluated to determine changes from population-based NTA to cancer-based NTA. The OCM NTA methodology was deconstructed to apply the NTA at a cancer type level. We performed a simulation exercise by applying cancer specific NTA methodology systematically to the claims and performance data. We then evaluated the impact of NTA on the EOM cancer types. Results: 20.95% of the TCOC was attributed to novel therapy expenditures in the OCM for all cancer types (range 0.0% - 49.4%) vs 24.2% (range - 3.5% - 43.7%) of TCOC for the EOM cancer types (high-risk breast, colon, lung, high-risk prostate, myeloma, lymphoma and chronic leukemia) in the same time-frame. 75.5% of the novel therapy expenditures in the OCM came from the 7 EOM cancers. In the OCM only 31.8% of eligible performance periods received a NTA. Had the NTA been applied at the cancer type level, 49.5% of eligible episodes would have received an adjustment. The top cancers with the most novel therapy use as a percentage of TCOC were lung, myeloma and high-risk/castrate-resistant prostate. The NTA for these practices adjusted the benchmark by an average of 0.56% (range - 0.21% to 1.1%) over 10 periods. When applied at a cancer type level, NTA increased the adjustment by 3 times to an average of 1.73% (range - 1.16% to 2.11%). Conclusions: The NTA applied at a cancer type level would have resulted in more instances where practices would have qualified for a benchmark adjustment. We believe that the EOM approach to NTA applied at a cancer type level is more favorable for participating practices and provides valuable financial protection when incorporating clinically appropriate novel therapy for cancer treatment. We commend CMMI for making improvements to the NTA risk adjustment methodology within the EOM.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
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    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2023
    detail.hit.zdb_id: 2005181-5
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