In:
Dermatology, S. Karger AG, Vol. 207, No. 1 ( 2003), p. 15-21
Abstract:
〈 i 〉 Background: 〈 /i 〉 In atopic eczema (AE), skin colonization with 〈 i 〉 Staphylococcus aureus 〈 /i 〉 is known to play a major triggering and possibly pathophysiological role. 〈 i 〉 Methods: 〈 /i 〉 In this open-labeled controlled side-to-side comparative trial, affected sites (flexures of both elbows) in 15 patients diagnosed as having generalized or localized AE were evaluated regarding 〈 i 〉 S. aureus 〈 /i 〉 colonization and clinical severity of AE over a 2-week period. Flexures of the elbows were covered with silver-coated textiles on one arm and cotton on the other for 7 days followed by a 7-day control period. 〈 i 〉 Results: 〈 /i 〉 A highly significant decrease in 〈 i 〉 S. aureus 〈 /i 〉 colonization could be seen on the site covered by the silver-coated textile already 2 days after initiation lasting until the end of the treatment. Seven days after cessation, 〈 i 〉 S. aureus 〈 /i 〉 density remained significantly lower compared to baseline. In addition, significantly lower numbers of 〈 i 〉 S. aureus 〈 /i 〉 were observed on the silver-coated textile site in comparison to cotton at the end of treatment as well as at the time point of control. Clinical improvement correlated with the reduction of 〈 i 〉 S. aureus 〈 /i 〉 colonization. 〈 i 〉 Conclusion: 〈 /i 〉 A superior improvement achieved by silver-coated compared to cotton textiles paralleled a potent anti- 〈 i 〉 S.-aureus 〈 /i 〉 effect.
Type of Medium:
Online Resource
ISSN:
1018-8665
,
1421-9832
Language:
English
Publisher:
S. Karger AG
Publication Date:
2003
detail.hit.zdb_id:
1482189-8
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