In:
Practical medicine, LLC Praktika, Vol. 18, No. 6 ( 2020), p. 128-132
Abstract:
Antibiotic resistance and resistome of intestinal strains of Kl. pneumoniae colonizing healthy babies in maternity hospitals were studied. According to the results of phenotype studies, Kl. pneumoniae in 92,3% of cases were ESBL producers and showed resistance to ampicillin, amoxiclav, co-trimoxazole, less to ciprofloxacin and nitrofurantoin. 90% of intestinal Kl. pneumoniae had multiple resistance to antimicrobial drugs. According to a genome-wide study, beta-lactamase genes were found in all strains. blaOXA-1 was found in 60%, blaTEM-30 in 70%, blaCTX-M-15 in 70%, blaSHV in 100% of the strains. Genes for resistance to aminoglycosides were found in 90%, fluoroquinolones — in 40%, sulfonamides — in 80%, chloramphenicol — in 70%, tetracycline — in 50%, and trimethoprim – in 70% of Kl. pneumoniae strains.
Type of Medium:
Online Resource
ISSN:
2072-1757
,
2307-3217
Uniform Title:
Антибиотикорезистентность кишечных штаммов Kl. pneumoniae, выделенных у новорожденных в родильном доме
DOI:
10.32000/2072-1757-2020-6-128-132
Language:
Unknown
Publisher:
LLC Praktika
Publication Date:
2020
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