In:
Cancer Research, American Association for Cancer Research (AACR), Vol. 79, No. 4_Supplement ( 2019-02-15), p. P3-03-39-P3-03-39
Abstract:
Nowadays, sentinel lymph node biopsy (SLNB) is one of the basic methods for diagnosing the lesion of regional lymph nodes (LN) and it is recommended by experts as a standard method in determining the prevalence of the disease in breast cancer patients (BC). The aim of the study was the possibility of sentinel lymph node biopsy after surgery with removal of the primary tumor. Materials and methods The study was conducted in the N.N. Petrov's National Medical Center of Oncology from 2013 to 2018. SLNB was performed in patients who had a primary tumorectomy in another medical institution. The study included patients with the stage cN0. Radionuclide imaging of the sentinel lymph nodes (SLN) was performed in 37 patients with breast cancer. The injection of radiopharmaceuticals in postoperative scar was performed before the biopsy. Median of the period between the operations was 21 days (14 to 30 days). Results After injection, the image of SLN was obtained in 91.9% (34 of 37) of patients. During the operation, 1-5 sentinel lymph nodes were visualized. The lesion of the sentinel lymph nodes (N+) was detected in 21.6% (8) patients, N0 in 78.4% (29) patients, respectively. There is no data for locoregional relapse for the period of observation from 2014 to nowadays. Conclusions The obtained results are comparable with the results of sentinel lymph node biopsy in primary patients with breast cancer stage cN0. This indicates the possibility of biopsy after surgery with removal of the primary tumor. Citation Format: Zhiltsova E, Krivorotko P, Dashayan G, Emelyanov A, Tabagua T, Bessonov A, Ivanova O, Kanaev S, Novikov S, Krzivickiyi P, Komayachov A, Nikolaev K, Gigolaeva L, Zernov K, Semiglazov V. Sentinel lymph node biopsy after surgery with removal of the primary tumor [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2019;79(4 Suppl):Abstract nr P3-03-39.
Type of Medium:
Online Resource
ISSN:
0008-5472
,
1538-7445
DOI:
10.1158/1538-7445.SABCS18-P3-03-39
Language:
English
Publisher:
American Association for Cancer Research (AACR)
Publication Date:
2019
detail.hit.zdb_id:
2036785-5
detail.hit.zdb_id:
1432-1
detail.hit.zdb_id:
410466-3
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