In:
Acta Paediatrica, Wiley, Vol. 112, No. 3 ( 2023-03), p. 496-504
Abstract:
To describe the relationship between loss of control events in preschoolers with asthma and persistence of disease. Methods We reviewed medical records of children 〈 6 years diagnosed with asthma in 2018 to assess loss of control events during three years of follow‐up. Asthma persistency was defined by redeem of short‐acting β2‐agonist or asthma controllers within one year after the end of follow‐up. Logistic regression models were applied to analyse the association between loss of control events and persistence of asthma. Results We included 172 patients (median age 1.8 years), whereof 126 (73.3%) experienced a loss of control event and 87 (50.6%) had asthma one year after the end of follow‐up. Any loss of control event was associated with persistence of asthma adjusted for controller treatment at inclusion, prior exacerbations, atopic comorbidity and caesarean section: aOR, 10.9 (95% CI, 3.9–34.6), p 〈 0.001. This was also significant restricted to events in the first year of follow‐up: 3.52 (1.50–8.67), p 〈 0.01 and among children only experiencing one event: 6.4 (1.7–27.3), p = 0.01. Conclusion Loss of control events during a 3‐year period among preschoolers with asthma are closely related to disease persistency, which may aid clinicians to assess risk of persistent asthma in young children.
Type of Medium:
Online Resource
ISSN:
0803-5253
,
1651-2227
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
1492629-5
detail.hit.zdb_id:
1501466-6
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