In:
Journal of Clinical Laboratory Analysis, Wiley, Vol. 32, No. 6 ( 2018-07)
Abstract:
Enhanced recovery after surgery ( ERAS ) programs, following a variety of perioperative treatments with evidence‐based medical evidence, has indicated its validity to accelerate rehabilitation in a wide variety of surgical procedures. This randomized controlled trial ( RCT ) study was implemented to verify the safety and efficacy of the perioperative effects in patients undergoing hepatectomy with ERAS or with conventional surgery ( CS ). Methods From August 2016 to November 2017, according to the inclusion criteria, 160 patients with liver diseases were suitable for participating in this experiment. Patients before liver resection were randomized into ERAS group (n = 80) and CS group (n = 80), and then the outcome measures were compared between the two groups. Results Enhanced recovery after surgery group had significantly less complications than CS group ( P = .009). Compared with CS group, patients in ERAS group had low peak of WBC s in postoperative day ( POD 1), ALT in POD 1 and POD 3 ( P 〈 .05), high value of ALB in POD 3 and POD 5 ( P 〈 .05), less pain and higher patient satisfaction ( P 〈 .001), earlier exhaust, oral feeding, ambulation and extubation time ( P 〈 .05),and also had less hospital stay and cost ( P 〈 .001). There were no significant differences in readmission rate ( 〈 30 days) between two groups ( P = .772). Conclusions Enhanced recovery after surgery programs applied to patients undergoing hepatectomy can safely and effectively relieve stress response, reduce the incidence of complications, improve patient satisfaction, accelerate patient recovery, reduce financial burden, and bring economic benefits.
Type of Medium:
Online Resource
ISSN:
0887-8013
,
1098-2825
DOI:
10.1002/jcla.2018.32.issue-6
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2001635-9
Bookmarklink