In:
Science, American Association for the Advancement of Science (AAAS), Vol. 346, No. 6213 ( 2014-11-28), p. 1109-1113
Abstract:
Mitochondria, the power houses of the cell, contain their own genome. Nevertheless, the majority of their constituent proteins are encoded by nuclear genes and are translated in the cytosol. During the cell cycle, a cell needs to duplicate each of its constituent parts and organelles. Surprisingly, it has never been clear how or whether mitochondrial protein import is linked with the cell cycle. Harbauer et al. (see the Perspective by Schulz and Rehling) now show that one of the main conduits for mitochondrial protein import is directly regulated by phosphorylation during mitosis, and that this in turn promotes respiratory activity. Science , this issue p. 1109
Type of Medium:
Online Resource
ISSN:
0036-8075
,
1095-9203
DOI:
10.1126/science.1261253
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2014
detail.hit.zdb_id:
128410-1
detail.hit.zdb_id:
2066996-3
detail.hit.zdb_id:
2060783-0
SSG:
11
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