In:
Scientific Reports, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2021-05-18)
Abstract:
This study aimed to investigate the effect of intraoperative fluid volume on the postoperative ileus (POI) recovery period. A retrospective review of the Korean robot-assisted radical cystectomy database identified 718 patients who underwent robot-assisted radical cystectomy (RARC). Regression analyses were performed to identify the associations between the amount of intraoperative fluid administration (crystalloid/colloid/total), POI period (time to flatus/bowel movements), and length of hospital stay (LOS) after adjusting for covariates. In addition, we analyzed the risk factors for gastrointestinal complications and prolonged POI using a logistic regression model. An increasing volume of the administered crystalloid/total fluid was associated with prolonged POI (crystalloid R 2 = 0.0725 and P 〈 0.0001; total amount R 2 = 0.0812 and P 〈 0.0001), and the total fluid volume was positively associated with the LOS (R 2 = 0.099 and P 〈 0.0001). The crystalloid amount was a risk factor for prolonged POI (P 〈 0.001; odds ratio, 1.361; 95% confidence interval, 1.133–1.641; P 〈 0.001). In the context of RARC, increased intravenous fluids are associated with prolonged POI and longer LOS.
Type of Medium:
Online Resource
ISSN:
2045-2322
DOI:
10.1038/s41598-021-89806-z
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2021
detail.hit.zdb_id:
2615211-3
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