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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, Daniel J ; Abdelmohsen, Kotb ; Abe, Akihisa ; [et al.]

Informa UK Limited ; 2016

In: Autophagy Vol. 12, No. 1 ( 2016-01-02), p. 1-222

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In: Autophagy, Informa UK Limited, Vol. 12, No. 1 ( 2016-01-02), p. 1-222

Type of Medium: Online Resource

ISSN: 1554-8627 , 1554-8635

URL: Article

DOI: 10.1080/15548627.2015.1100356

Language: English

Publisher: Informa UK Limited

Publication Date: 2016

detail.hit.zdb_id: 2262043-6

SSG: 12

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The Genetic Architecture of Depression in Individuals of East Asian Ancestry : A Genome-Wide Association Study

Giannakopoulou, Olga ; Lin, Kuang ; Meng, Xiangrui ; [et al.]

American Medical Association (AMA) ; 2021

In: JAMA Psychiatry Vol. 78, No. 11 ( 2021-11-01), p. 1258-

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In: JAMA Psychiatry, American Medical Association (AMA), Vol. 78, No. 11 ( 2021-11-01), p. 1258-

Type of Medium: Online Resource

ISSN: 2168-622X

URL: Article

DOI: 10.1001/jamapsychiatry.2021.2099

Language: English

Publisher: American Medical Association (AMA)

Publication Date: 2021

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Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial

Holman, Rury R ; Coleman, Ruth L ; Chan, Juliana C N ; [et al.]

Elsevier BV ; 2017

In: The Lancet Diabetes & Endocrinology Vol. 5, No. 11 ( 2017-11), p. 877-886

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In: The Lancet Diabetes & Endocrinology, Elsevier BV, Vol. 5, No. 11 ( 2017-11), p. 877-886

Type of Medium: Online Resource

ISSN: 2213-8587

URL: Article

DOI: 10.1016/S2213-8587(17)30309-1

Language: English

Publisher: Elsevier BV

Publication Date: 2017

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Functional Trachea Reconstruction Using 3D‐Bioprinted Native‐Like Tissue Architecture Based on Designable Tissue‐Specific Bioinks

Huo, Yingying ; Xu, Yong ; Wu, Xiaodi ; [et al.]

Wiley ; 2022

In: Advanced Science Vol. 9, No. 29 ( 2022-10)

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In: Advanced Science, Wiley, Vol. 9, No. 29 ( 2022-10)

Abstract: Functional segmental trachea reconstruction remains a remarkable challenge in the clinic. To date, functional trachea regeneration with alternant cartilage‐fibrous tissue‐mimetic structure similar to that of the native trachea relying on the three‐dimensional (3D) bioprinting technology has seen very limited breakthrough. This fact is mostly due to the lack of tissue‐specific bioinks suitable for both cartilage and vascularized fibrous tissue regeneration, as well as the need for firm interfacial integration between stiff and soft tissues. Here, a novel strategy is developed for 3D bioprinting of cartilage‐vascularized fibrous tissue‐integrated trachea ( CVFIT ), utilizing photocrosslinkable tissue‐specific bioinks. Both cartilage‐ and fibrous tissue‐specific bioinks created by this study provide suitable printability, favorable biocompatibility, and biomimetic microenvironments for chondrogenesis and vascularized fibrogenesis based on the multicomponent synergistic effect through the hybrid photoinitiated polymerization reaction. As such, the tubular analogs are successfully bioprinted and the ring‐to‐ring alternant structure is tightly integrated by the enhancement of interfacial bonding through the amidation reaction. The results from both the trachea regeneration and the in situ trachea reconstruction demonstrate the satisfactory tissue‐specific regeneration along with realization of mechanical and physiological functions. This study thus illustrates the 3D‐bioprinted native tissue‐like trachea as a promising alternative for clinical trachea reconstruction.

Type of Medium: Online Resource

ISSN: 2198-3844 , 2198-3844

URL: Issue

URL: Article

DOI: 10.1002/advs.v9.29

DOI: 10.1002/advs.202202181

Language: English

Publisher: Wiley

Publication Date: 2022

detail.hit.zdb_id: 2808093-2

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Instant trachea reconstruction using 3D-bioprinted C-shape biomimetic trachea based on tissue-specific matrix hydrogels

Sun, Yuyan ; Huo, Yingying ; Ran, Xinyue ; [et al.]

Elsevier BV ; 2024

In: Bioactive Materials Vol. 32 ( 2024-02), p. 52-65

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In: Bioactive Materials, Elsevier BV, Vol. 32 ( 2024-02), p. 52-65

Type of Medium: Online Resource

ISSN: 2452-199X

URL: Article

DOI: 10.1016/j.bioactmat.2023.09.011

Language: English

Publisher: Elsevier BV

Publication Date: 2024

detail.hit.zdb_id: 2970496-0

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Video3.MOV

Xu, Wei ; Wang, Tao ; Wang, Yahui ; [et al.]

Frontiers Media SA ; 2022

In: Frontiers in Bioengineering and Biotechnology Vol. 10 ( 2022-4-14)

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In: Frontiers in Bioengineering and Biotechnology, Frontiers Media SA, Vol. 10 ( 2022-4-14)

Abstract: Cell–hydrogel constructs are frequently used as injectable platforms for irregular cartilage regeneration. However, cell–hydrogel constructs have obvious disadvantages, such as long culture times, high probability of infection, and poor cartilage formation capacity, significantly limiting their clinical translation. In this study, we aimed to develop a novel injectable platform comprising engineered cartilage gel (ECG) and gelatin methacrylate (GelMA) to improve cartilage regeneration. We first prepared an ECG by cutting the in vitro engineered cartilage sheet into pieces. The chondrocytes and ECG were evenly encapsulated into GelMA to form Cell-GelMA and ECG-GelMA constructs. The ECG-GelMA construct exhibited preferred gel characteristics and superior biocompatibility compared with the Cell-GelMA construct counterpart. After subcutaneous implantation in nude mice and goat, both gross views and histological evaluations showed that the ECG-GelMA construct achieved more homogenous, stable, and mature cartilage regeneration than the Cell-GelMA construct. Immunological evaluations showed that ECG-GelMA had a mitigatory immunologic reaction than the Cell-GelMA construct. Overall, the results suggest that the ECG-GelMA is a promising injectable platform for cartilage regeneration that may advance clinical translation.

Type of Medium: Online Resource

ISSN: 2296-4185

URL: Article

DOI: 10.3389/fbioe.2022.884036

DOI: 10.3389/fbioe.2022.884036.s001

DOI: 10.3389/fbioe.2022.884036.s002

DOI: 10.3389/fbioe.2022.884036.s003

DOI: 10.3389/fbioe.2022.884036.s004

DOI: 10.3389/fbioe.2022.884036.s005

DOI: 10.3389/fbioe.2022.884036.s006

DOI: 10.3389/fbioe.2022.884036.s007

DOI: 10.3389/fbioe.2022.884036.s008

DOI: 10.3389/fbioe.2022.884036.s009

DOI: 10.3389/fbioe.2022.884036.s010

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2022

detail.hit.zdb_id: 2719493-0

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Functional Trachea Reconstruction Using 3D‐Bioprinted Native‐Like Tissue Architecture Based on Designable Tissue‐Specific Bioinks (Adv. Sci. 29/2022)

Huo, Yingying ; Xu, Yong ; Wu, Xiaodi ; [et al.]

Wiley ; 2022

In: Advanced Science Vol. 9, No. 29 ( 2022-10)

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In: Advanced Science, Wiley, Vol. 9, No. 29 ( 2022-10)

Type of Medium: Online Resource

ISSN: 2198-3844 , 2198-3844

URL: Issue

URL: Article

DOI: 10.1002/advs.v9.29

DOI: 10.1002/advs.202270184

Language: English

Publisher: Wiley

Publication Date: 2022

detail.hit.zdb_id: 2808093-2

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GW26-e2467 Risk of hemorrhagic and ischemic stroke for dual antiplatelet therapy and new generation oral anticoagulants in patients with acute coronary syndrome

Gao, Fei ; Shen, Hua ; Wang, Zhijian ; [et al.]

Elsevier BV ; 2015

In: Journal of the American College of Cardiology Vol. 66, No. 16 ( 2015-10), p. C158-

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In: Journal of the American College of Cardiology, Elsevier BV, Vol. 66, No. 16 ( 2015-10), p. C158-

Type of Medium: Online Resource

ISSN: 0735-1097

URL: Article

DOI: 10.1016/j.jacc.2015.06.605

RVK:

XA 17760

Language: English

Publisher: Elsevier BV

Publication Date: 2015

detail.hit.zdb_id: 1468327-1

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DataSheet_1.pdf

Zhang, Le ; Badai, Jiayidaer ; Wang, Guan ; [et al.]

Frontiers Media SA ; 2023

In: Frontiers in Immunology Vol. 14 ( 2023-2-7)

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In: Frontiers in Immunology, Frontiers Media SA, Vol. 14 ( 2023-2-7)

Abstract: Central nervous system (CNS) diseases, such as neurodegenerative disorders and brain diseases caused by acute injuries, are important, yet challenging to study due to disease lesion locations and other complexities. Methods Utilizing the powerful method of spatial transcriptome analysis together with novel algorithms we developed for the study, we report here for the first time a 3D trajectory map of gene expression changes in the brain following acute neural injury using a mouse model of intraventricular hemorrhage (IVH). IVH is a common and representative complication after various acute brain injuries with severe mortality and mobility implications. Results Our data identified three main 3D global pseudospace-time trajectory bundles that represent the main neural circuits from the lateral ventricle to the hippocampus and primary cortex affected by experimental IVH stimulation. Further analysis indicated a rapid response in the primary cortex, as well as a direct and integrated effect on the hippocampus after IVH stimulation. Discussion These results are informative for understanding the pathophysiological changes, including the spatial and temporal patterns of gene expression changes, in IVH patients after acute brain injury, strategizing more effective clinical management regimens, and developing novel bioinformatics strategies for the study of other CNS diseases. The algorithm strategies used in this study are searchable via a web service ( www.combio-lezhang.online/3dstivh/home ).

Type of Medium: Online Resource

ISSN: 1664-3224

URL: Article

DOI: 10.3389/fimmu.2023.1123652

DOI: 10.3389/fimmu.2023.1123652.s001

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2023

detail.hit.zdb_id: 2606827-8

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Tobacco smoking and risks of more than 470 diseases in China: a prospective cohort study

Chan, Ka Hung ; Wright, Neil ; Xiao, Dan ; [et al.]

Elsevier BV ; 2022

In: The Lancet Public Health Vol. 7, No. 12 ( 2022-12), p. e1014-e1026

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In: The Lancet Public Health, Elsevier BV, Vol. 7, No. 12 ( 2022-12), p. e1014-e1026

Type of Medium: Online Resource

ISSN: 2468-2667

URL: Article

DOI: 10.1016/S2468-2667(22)00227-4

Language: English

Publisher: Elsevier BV

Publication Date: 2022

detail.hit.zdb_id: 2917200-7

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