In:
Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 26, No. 6 ( 2005-06), p. 540-547
Abstract:
To determine the mortality, hospital stay, and total hospital charges and cost of hospitalization attributable to candidemia by comparing patients with candidemia with control-patients who have otherwise similar illnesses. Prior studies lack broad patient and hospital representation or cost-related information that accurately reflects current medical practices. Design: Our case-control study included case-patients with candidemia and their cost-related data, ascertained from laboratory-based candidemia surveillance conducted among all residents of Connecticut and Baltimore and Baltimore County, Maryland, during 1998 to 2000. Control-patients were matched on age, hospital type, admission year, discharge diagnoses, and duration of hospitalization prior to candidemia onset. Results: We identified 214 and 529 sets of matched case-patients and control-patients from the two locations, respectively. Mortality attributable to candidemia ranged between 19% and 24%. On multivariable analysis, candidemia was associated with mortality (OR, 5.3 for Connecticut and 8.5 for Baltimore and Baltimore County; P 〈 .05), whereas receiving adequate treatment was protective (OR, 0.5 and 0.4 for the two locations, respectively; P 〈 .05). Candidemia itself did not increase the total hospital charges and cost of hospitalization; when treatment status was accounted for, having received adequate treatment for candidemia significantly increased the total hospital charges and cost of hospitalization ($6,000 to $29,000 and $3,000 to $22,000, respectively) and the length of stay (3 to 13 days). Conclusion: Our findings underscore the burden of candidemia, particularly regarding the risk of death, length of hospitalization, and cost associated with treatment ( Infect Control Hosp Epidemiol 2005;26:540-547).
Type of Medium:
Online Resource
ISSN:
0899-823X
,
1559-6834
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
2005
detail.hit.zdb_id:
2106319-9
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