In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 1 ( 2021-1-14), p. e0244006-
Abstract:
In this study, we examined the role of the eastern bent-winged bat (Miniopterus fuliginosus) in the dispersion of bat adenovirus and bat alphacoronavirus in east Asia, considering their gene flows and divergence times (based on deep-sequencing data), using bat fecal guano samples. Bats in China moved to Jeju Island and/or Taiwan in the last 20,000 years via the Korean Peninsula and/or Japan. The phylogenies of host mitochondrial D-loop DNA was not significantly congruent with those of bat adenovirus (m 2 XY = 0.07, p = 0.08), and bat alphacoronavirus (m 2 XY = 0.48, p = 0.20). We estimate that the first divergence time of bats carrying bat adenovirus in five caves studied (designated as K1, K2, JJ, N2, and F3) occurred approximately 3.17 million years ago. In contrast, the first divergence time of bat adenovirus among bats in the 5 caves was estimated to be approximately 224.32 years ago. The first divergence time of bats in caves CH, JJ, WY, N2, F1, F2, and F3 harboring bat alphacoronavirus was estimated to be 1.59 million years ago. The first divergence time of bat alphacoronavirus among the 7 caves was estimated to be approximately 2,596.92 years ago. The origin of bat adenovirus remains unclear, whereas our findings suggest that bat alphacoronavirus originated in Japan. Surprisingly, bat adenovirus and bat alphacoronavirus appeared to diverge substantially over the last 100 years, even though our gene-flow data indicate that the eastern bent-winged bat serves as an important natural reservoir of both viruses.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0244006
DOI:
10.1371/journal.pone.0244006.g001
DOI:
10.1371/journal.pone.0244006.g002
DOI:
10.1371/journal.pone.0244006.g003
DOI:
10.1371/journal.pone.0244006.g004
DOI:
10.1371/journal.pone.0244006.g005
DOI:
10.1371/journal.pone.0244006.g006
DOI:
10.1371/journal.pone.0244006.t001
DOI:
10.1371/journal.pone.0244006.t002
DOI:
10.1371/journal.pone.0244006.t003
DOI:
10.1371/journal.pone.0244006.t004
DOI:
10.1371/journal.pone.0244006.s001
DOI:
10.1371/journal.pone.0244006.s002
DOI:
10.1371/journal.pone.0244006.s003
DOI:
10.1371/journal.pone.0244006.s004
DOI:
10.1371/journal.pone.0244006.s005
DOI:
10.1371/journal.pone.0244006.s006
DOI:
10.1371/journal.pone.0244006.s007
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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