In:
The Journal of Dermatology, Wiley, Vol. 43, No. 8 ( 2016-08), p. 900-905
Abstract:
The clinical and laboratory factors related to Pru p 7 sensitization in peach allergy, compared with those associated with sensitization to Pru p 1, which is related to pollen‐food allergy syndrome ( PFAS ), have still not been clarified. The aim of the present study was to identify the clinical and laboratory features associated with sensitization to Pru p 7. Fifty patients (male : female, 14:36; mean age, 31.8 years) with peach allergy were enrolled in this study. Specific immunoglobulin E ( sIgE ) against the purified nP ru p 7 was measured by enzyme‐linked immunoassay, whereas using Immuno CAP , sIgE levels against peach, rP ru p 1, rP ru p 3 and rP ru p 4 were measured. Correlations between the clinical characteristics of peach allergy and sensitization to the allergens were statistically analyzed. In 50 patients with peach allergy, 13 and 33 patients were sensitized with nP ru p 7 and rP ru p 1, respectively. Laryngeal tightness, conjunctival injection, facial edema, eyelid edema and urticaria were significantly associated with Pru p 7 sensitization. In contrast, oropharyngeal symptoms were strongly related to Pru p 1 sensitization but were significantly less common in the Pru p 7‐positive group. Co‐sensitization to the representative pollens related to PFAS , such as alder pollens, was significantly related to Pru p 1 sensitization, but not Pru p 7 sensitization. Along with the absence of co‐sensitization to pollens related to PFAS , facial edema and especially eyelid edema after the ingestion of peaches could be a predictive factor for sensitization to Pru p 7.
Type of Medium:
Online Resource
ISSN:
0385-2407
,
1346-8138
DOI:
10.1111/jde.2016.43.issue-8
DOI:
10.1111/1346-8138.13316
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2222121-9
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