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Evaluation of Impact of Water Deficit on Morphological Characters and Yield of Alfalfa (Medicago sativa) Cultivars in Khuzestan Conditions - Ahwaz

Behnamfar, K. ; Siadat, S. A. ; Bakhshandeh, A. M. ; [et al.]

CASRP: Center of Advanced Scientific Research and Publications ; 2015

In: Journal of Crop production and processing Vol. 5, No. 17 ( 2015-12-01), p. 171-180

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In: Journal of Crop production and processing, CASRP: Center of Advanced Scientific Research and Publications, Vol. 5, No. 17 ( 2015-12-01), p. 171-180

Type of Medium: Online Resource

ISSN: 2251-8517

URL: Article

DOI: 10.18869/acadpub.jcpp.5.17.171

Language: Persian

Publisher: CASRP: Center of Advanced Scientific Research and Publications

Publication Date: 2015

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Prognostic significance of SF3B1 mutations in patients with myelodysplastic syndromes: A meta-analysis

Jafari, Pourya Arbab ; Sadeghian, Mohammad Hadi ; Miri, Hamid Heidarian ; [et al.]

Elsevier BV ; 2020

In: Critical Reviews in Oncology/Hematology Vol. 145 ( 2020-01), p. 102832-

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In: Critical Reviews in Oncology/Hematology, Elsevier BV, Vol. 145 ( 2020-01), p. 102832-

Type of Medium: Online Resource

ISSN: 1040-8428

URL: Article

DOI: 10.1016/j.critrevonc.2019.102832

Language: English

Publisher: Elsevier BV

Publication Date: 2020

detail.hit.zdb_id: 2025731-4

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Health system performance in Iran: a systematic analysis for the Global Burden of Disease Study 2019

Farzadfar, Farshad ; Naghavi, Mohsen ; Sepanlou, Sadaf G ; [et al.]

Elsevier BV ; 2022

In: The Lancet Vol. 399, No. 10335 ( 2022-04), p. 1625-1645

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In: The Lancet, Elsevier BV, Vol. 399, No. 10335 ( 2022-04), p. 1625-1645

Type of Medium: Online Resource

ISSN: 0140-6736

URL: Article

DOI: 10.1016/S0140-6736(21)02751-3

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2022

detail.hit.zdb_id: 2067452-1

detail.hit.zdb_id: 3306-6

detail.hit.zdb_id: 1476593-7

SSG: 5,21

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The Effect of Topography and Irrigation on Soil Development and Clay Mineral Diversity of Khuzestan's Gypsic Soils

Abdoli, Y. ; Jafari, S. ; Dept. of Soil Sci., Ramin Agric. and Natural Resour. Univ. of Khuzestan, Ahvaz, Iran.

Academic World Research ; 2018

In: Journal of Water and Soil Science Vol. 22, No. 1 ( 2018-6-01), p. 387-403

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In: Journal of Water and Soil Science, Academic World Research, Vol. 22, No. 1 ( 2018-6-01), p. 387-403

Type of Medium: Online Resource

ISSN: 2476-3594 , 2476-5554

URL: Article

DOI: 10.29252/jstnar.22.1.387

Language: Persian

Publisher: Academic World Research

Publication Date: 2018

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Antiproliferative and apoptotic effects of conditioned medium released from human amniotic epithelial stem cells on breast and cervical cancer cells

Jafari, Ameneh ; Niknejad, Hassan ; Rezaei-Tavirani, Mostafa ; [et al.]

SAGE Publications ; 2023

In: International Journal of Immunopathology and Pharmacology Vol. 37 ( 2023-12), p. 039463202211507-

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In: International Journal of Immunopathology and Pharmacology, SAGE Publications, Vol. 37 ( 2023-12), p. 039463202211507-

Abstract: Human amniotic membrane (hAM) and its cells have been proposed for several clinical applications, including cancer therapy. However, reports on the anticancer effects of human amniotic epithelial stem cells-conditioned media (hAECs-CM) are limited. This work aims to evaluate the anticancer effects of hAECs-CM on cervical cancer and breast cancer cell lines in vitro . Methods Human term placentas were gained from uncomplicated Cesarean sections from healthy donor women. After amnion peeling from the chorion, its epithelial stem cells were isolated and cultured, and its conditioned medium (CM) was collected for experiments. MTT assay was performed to assess cancer cells viability. Migration rate of cancer cells was examined via wound healing assay. Cell-cycle distribution and apoptosis were determined using flow cytometry. Results Based on MTT assay hAECs-CM was cytotoxic against cancerous cell lines in a dose-time-dependent manner. After 48 h of treatment with hAECs-CM pure, the cell viability of breast cancer cells includes MCF-7 and MDA-MB-231 reached to 73.2% and 65.5%, respectively. In the same situation, HeLa cervical cancer cell line revealed the lowest viability by 47.3%. The wound-healing assay displayed an incomplete wound closure of scratched MDA-MB-231 cells and significant inhibition of cell migration after hAECs-CM treatment. The results also revealed that hAECs-CM exerted anti-proliferation activity by prompting cell cycle arrest and apoptosis of cancer cells. Conclusions: hAECs-CM is a potent candidate for inducing apoptosis and simultaneously inhibition of the proliferation and migration of cancer cells via inhibiting cell cycle blockade.

Type of Medium: Online Resource

ISSN: 0394-6320 , 2058-7384

URL: Article

DOI: 10.1177/03946320221150712

Language: English

Publisher: SAGE Publications

Publication Date: 2023

detail.hit.zdb_id: 2505963-4

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Measurement of the liver iron concentration in transfusional iron overload by MRI R2* and by high-transition-temperature superconducting magnetic susceptometry

Sheth, Sujit ; Allen, Christopher J. ; Farrell, David E. ; [et al.]

Elsevier BV ; 2019

In: Clinical Imaging Vol. 55 ( 2019-05), p. 65-70

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In: Clinical Imaging, Elsevier BV, Vol. 55 ( 2019-05), p. 65-70

Type of Medium: Online Resource

ISSN: 0899-7071

URL: Article

DOI: 10.1016/j.clinimag.2019.01.012

Language: English

Publisher: Elsevier BV

Publication Date: 2019

detail.hit.zdb_id: 2004578-5

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Free‐breathing high isotropic resolution quantitative susceptibility mapping ( QSM ) of liver using 3D multi‐echo UTE cones acquisition and respiratory motion‐resolved image reconstruction

Kang, MungSoo ; Behr, Gerald G. ; Jafari, Ramin ; [et al.]

Wiley ; 2023

In: Magnetic Resonance in Medicine Vol. 90, No. 5 ( 2023-11), p. 1844-1858

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In: Magnetic Resonance in Medicine, Wiley, Vol. 90, No. 5 ( 2023-11), p. 1844-1858

Abstract: To enable free‐breathing and high isotropic resolution liver quantitative susceptibility mapping (QSM) using 3D multi‐echo UTE cones acquisition and respiratory motion‐resolved image reconstruction. Methods Using 3D multi‐echo UTE cones MRI, a respiratory motion was estimated from the k‐space center of the imaging data. After sorting the k‐space data with estimated motion, respiratory motion state‐resolved reconstruction was performed for multi‐echo data followed by nonlinear least‐squares fitting for proton density fat fraction (PDFF), , and fat‐corrected B 0 field maps. PDFF and B 0 field maps were subsequently used for QSM reconstruction. The proposed method was compared with motion‐averaged (gridding) reconstruction and conventional 3D multi‐echo Cartesian MRI in moving gadolinium phantom and in vivo studies. Region of interest (ROI)‐based linear regression analysis was performed on these methods to investigate correlations between gadolinium concentration and QSM in the phantom study and between and QSM in in vivo study. Results Cones with motion‐resolved reconstruction showed sharper image quality compared to motion‐averaged reconstruction with a substantial reduction of motion artifacts in both moving phantom and in vivo studies. For ROI‐based linear regression analysis of the phantom study, susceptibility values from cones with motion‐resolved reconstruction ( = 0.31 0.05, = 0.999) and Cartesian without motion ( = 0.32 0.04, = 1.000) showed linear relationships with gadolinium concentrations and showed good agreement with each other. For in vivo, motion‐resolved reconstruction showed higher goodness of fit ( = 0.00261 0.524, = 0.977) compared to motion‐averaged reconstruction ( = 0.0021 0.572, = 0.723) in ROI‐based linear regression analysis between and QSM. Conclusion Feasibility of free‐breathing liver QSM was demonstrated with motion‐resolved 3D multi‐echo UTE cones MRI, achieving high isotropic resolution currently unachievable in conventional Cartesian MRI.

Type of Medium: Online Resource

ISSN: 0740-3194 , 1522-2594

URL: Issue

URL: Article

DOI: 10.1002/mrm.v90.5

DOI: 10.1002/mrm.29779

Language: English

Publisher: Wiley

Publication Date: 2023

detail.hit.zdb_id: 1493786-4

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Integrated quantitative susceptibility and R 2 * mapping for evaluation of liver fibrosis: An ex vivo feasibility study

Jafari, Ramin ; Hectors, Stefanie J. ; Koehne de González, Anne K. ; [et al.]

Wiley ; 2021

In: NMR in Biomedicine Vol. 34, No. 1 ( 2021-01)

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In: NMR in Biomedicine, Wiley, Vol. 34, No. 1 ( 2021-01)

Abstract: To develop a method for noninvasive evaluation of liver fibrosis, we investigated the differential sensitivities of quantitative susceptibility mapping (QSM) and R 2 * mapping using corrections for the effects of liver iron. Liver fibrosis is characterized by excessive accumulation of collagen and other extracellular matrix proteins. While collagen increases R 2 * relaxation, measures of R 2 * for fibrosis are confounded by liver iron, which may be present in the liver over a wide range of concentrations. The diamagnetic collagen contribution to susceptibility values measured by QSM is much less than the contribution of highly paramagnetic iron. In 19 ex vivo liver explants with and without fibrosis, QSM (χ), R 2 * and proton density fat fraction (PDFF) maps were constructed from multiecho gradient‐recalled echo (mGRE) sequence acquisition at 3 T. Median parameter values were recorded and differences between the MRI parameters in nonfibrotic vs. advanced fibrotic/cirrhotic samples were evaluated using Mann–Whitney U tests and receiver operating characteristic analyses. Logistic regression with stepwise feature selection was employed to evaluate the utility of combined MRI measurements for detection of fibrosis. Median R 2 * increased in fibrotic vs. nonfibrotic liver samples ( P = .041), while differences in χ and PDFF were nonsignificant ( P = .545 and P = .395, respectively). Logistic regression identified the combination of χ and R 2 * significant for fibrosis detection (logit [prediction] = −8.45 + 0.23 R 2 * − 28.8 χ). For this classifier, a highly significant difference between nonfibrotic vs. advanced fibrotic/cirrhotic samples was observed ( P = .002). The model exhibited an AUC of 0.909 ( P = .003) for detection of advanced fibrosis/cirrhosis, which was substantially higher compared with AUCs of the individual parameters (AUC 0.591–0.784). An integrated QSM and R 2 * analysis of mGRE 3 T imaging data is promising for noninvasive diagnostic assessment of liver fibrosis.

Type of Medium: Online Resource

ISSN: 0952-3480 , 1099-1492

URL: Issue

URL: Article

DOI: 10.1002/nbm.v34.1

DOI: 10.1002/nbm.4412

Language: English

Publisher: Wiley

Publication Date: 2021

detail.hit.zdb_id: 2002003-X

detail.hit.zdb_id: 1000976-0

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Composition and production rate of dental solid waste and associated management practices in Hamadan, Iran

Nabizadeh, Ramin ; Koolivand, Ali ; Jafari, Ahmad Jonidi ; [et al.]

SAGE Publications ; 2012

In: Waste Management & Research: The Journal for a Sustainable Circular Economy Vol. 30, No. 6 ( 2012-06), p. 619-624

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In: Waste Management & Research: The Journal for a Sustainable Circular Economy, SAGE Publications, Vol. 30, No. 6 ( 2012-06), p. 619-624

Abstract: The objective of this study was to identify the components, composition and production rate of dental solid waste and associated management practices in dental offices in Hamadan. A total of 28 offices, including ten general dentist offices, eight specialist dentist offices, five practical dentist offices and five denture maker offices were selected in a random way. Three samples from each selected type were taken and the waste was manually separated into 74 sub-fractions and each sub-fraction was weighed. The results showed that the total annual dental waste production in dental offices was 41947.43 kg. Domestic type, potentially infectious, chemical and pharmaceutical and toxic waste constituted 71.15, 21.40, 7.26 and 0.18%, respectively of this amount. Only seven fractions including gypsum, latex gloves, nylon, dental impression material, used medicine ampoules, saliva-contaminated paper towels and saliva ejectors constituted about 80% of the waste. It was also indicated that there were no effective activity for waste minimization, separation, reuse and recycling in dental offices and the management of sharps, potentially infectious waste and other hazardous waste was poor.

Type of Medium: Online Resource

ISSN: 0734-242X , 1096-3669

URL: Article

DOI: 10.1177/0734242X11412110

Language: English

Publisher: SAGE Publications

Publication Date: 2012

detail.hit.zdb_id: 1480483-9

detail.hit.zdb_id: 46937-3

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Clinical Applications and Anticancer Effects of Antimicrobial Peptides: From Bench to Bedside

Jafari, Ameneh ; Babajani, Amirhesam ; Sarrami Forooshani, Ramin ; [et al.]

Frontiers Media SA ; 2022

In: Frontiers in Oncology Vol. 12 ( 2022-2-23)

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In: Frontiers in Oncology, Frontiers Media SA, Vol. 12 ( 2022-2-23)

Abstract: Cancer is a multifaceted global health issue and one of the leading causes of death worldwide. In recent years, medical science has achieved great advances in the diagnosis and treatment of cancer. Despite the numerous advantages of conventional cancer therapies, there are major drawbacks including severe side effects, toxicities, and drug resistance. Therefore, the urgency of developing new drugs with low cytotoxicity and treatment resistance is increasing. Antimicrobial peptides (AMPs) have attracted attention as a novel therapeutic strategy for the treatment of various cancers, targeting tumor cells with less toxicity to normal tissues. In this review, we present the structure, biological function, and underlying mechanisms of AMPs. The recent experimental studies and clinical trials on anticancer peptides in different cancer types as well as the challenges of their clinical application have also been discussed.

Type of Medium: Online Resource

ISSN: 2234-943X

URL: Article

DOI: 10.3389/fonc.2022.819563

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2022

detail.hit.zdb_id: 2649216-7

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