In:
Digestive Surgery, S. Karger AG, Vol. 27, No. 5 ( 2010), p. 409-416
Abstract:
〈 i 〉 Aims: 〈 /i 〉 The aim of the study was to assess the long-term outcomes of the surgical-only management of gastric cancer (GC) patients treated in a single centre over 10-year span preceding introduction of multimodal therapy to the clinical practice. 〈 i 〉 Methods: 〈 /i 〉 Two hundred and one patients with pathologic confirmation of GC treated for resectable tumor mostly with curative intent were enrolled in the study. The analysis comprised a review of the medical histories, descriptions of the operations, results of histopathological studies and long-time survival. 〈 i 〉 Results: 〈 /i 〉 Median survival time and 5-year survival rate for patients with R0 vs. R1 and R2 resection were 3.85 years and 43.5% versus 0.86 years and 7.8%, respectively. Univariate analyses showed that 5-year survival rates were correlated with histopathological type according to Laurén, type of lymphadenectomy performed, spleen preservation, stage of disease and the degree of radical resection. Independent prognostic factors in multivariate analysis were: no residual tumor after resection, type of lymphadenectomy, depth of tumor invasion in the gastric wall and lymph nodes status. 〈 i 〉 Conclusions: 〈 /i 〉 Retrospective analysis of the long-term results of the surgical-only management of GC patients may be useful in assessment of the quality of medical services, especially prior to introduction of multimodal therapy.
Type of Medium:
Online Resource
ISSN:
0253-4886
,
1421-9883
Language:
English
Publisher:
S. Karger AG
Publication Date:
2010
detail.hit.zdb_id:
1468560-7
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