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  • 1
    Online Resource
    Online Resource
    American Meteorological Society ; 2023
    In:  Bulletin of the American Meteorological Society Vol. 104, No. 9 ( 2023-09), p. S1-S10
    In: Bulletin of the American Meteorological Society, American Meteorological Society, Vol. 104, No. 9 ( 2023-09), p. S1-S10
    Abstract: —J. BLUNDEN, T. BOYER, AND E. BARTOW-GILLIES Earth’s global climate system is vast, complex, and intricately interrelated. Many areas are influenced by global-scale phenomena, including the “triple dip” La Niña conditions that prevailed in the eastern Pacific Ocean nearly continuously from mid-2020 through all of 2022; by regional phenomena such as the positive winter and summer North Atlantic Oscillation that impacted weather in parts the Northern Hemisphere and the negative Indian Ocean dipole that impacted weather in parts of the Southern Hemisphere; and by more localized systems such as high-pressure heat domes that caused extreme heat in different areas of the world. Underlying all these natural short-term variabilities are long-term climate trends due to continuous increases since the beginning of the Industrial Revolution in the atmospheric concentrations of Earth’s major greenhouse gases. In 2022, the annual global average carbon dioxide concentration in the atmosphere rose to 417.1±0.1 ppm, which is 50% greater than the pre-industrial level. Global mean tropospheric methane abundance was 165% higher than its pre-industrial level, and nitrous oxide was 24% higher. All three gases set new record-high atmospheric concentration levels in 2022. Sea-surface temperature patterns in the tropical Pacific characteristic of La Niña and attendant atmospheric patterns tend to mitigate atmospheric heat gain at the global scale, but the annual global surface temperature across land and oceans was still among the six highest in records dating as far back as the mid-1800s. It was the warmest La Niña year on record. Many areas observed record or near-record heat. Europe as a whole observed its second-warmest year on record, with sixteen individual countries observing record warmth at the national scale. Records were shattered across the continent during the summer months as heatwaves plagued the region. On 18 July, 104 stations in France broke their all-time records. One day later, England recorded a temperature of 40°C for the first time ever. China experienced its second-warmest year and warmest summer on record. In the Southern Hemisphere, the average temperature across New Zealand reached a record high for the second year in a row. While Australia’s annual temperature was slightly below the 1991–2020 average, Onslow Airport in Western Australia reached 50.7°C on 13 January, equaling Australia's highest temperature on record. While fewer in number and locations than record-high temperatures, record cold was also observed during the year. Southern Africa had its coldest August on record, with minimum temperatures as much as 5°C below normal over Angola, western Zambia, and northern Namibia. Cold outbreaks in the first half of December led to many record-low daily minimum temperature records in eastern Australia. The effects of rising temperatures and extreme heat were apparent across the Northern Hemisphere, where snow-cover extent by June 2022 was the third smallest in the 56-year record, and the seasonal duration of lake ice cover was the fourth shortest since 1980. More frequent and intense heatwaves contributed to the second-greatest average mass balance loss for Alpine glaciers around the world since the start of the record in 1970. Glaciers in the Swiss Alps lost a record 6% of their volume. In South America, the combination of drought and heat left many central Andean glaciers snow free by mid-summer in early 2022; glacial ice has a much lower albedo than snow, leading to accelerated heating of the glacier. Across the global cryosphere, permafrost temperatures continued to reach record highs at many high-latitude and mountain locations. In the high northern latitudes, the annual surface-air temperature across the Arctic was the fifth highest in the 123-year record. The seasonal Arctic minimum sea-ice extent, typically reached in September, was the 11th-smallest in the 43-year record; however, the amount of multiyear ice—ice that survives at least one summer melt season—remaining in the Arctic continued to decline. Since 2012, the Arctic has been nearly devoid of ice more than four years old. In Antarctica, an unusually large amount of snow and ice fell over the continent in 2022 due to several landfalling atmospheric rivers, which contributed to the highest annual surface mass balance, 15% to 16% above the 1991–2020 normal, since the start of two reanalyses records dating to 1980. It was the second-warmest year on record for all five of the long-term staffed weather stations on the Antarctic Peninsula. In East Antarctica, a heatwave event led to a new all-time record-high temperature of −9.4°C—44°C above the March average—on 18 March at Dome C. This was followed by the collapse of the critically unstable Conger Ice Shelf. More than 100 daily low sea-ice extent and sea-ice area records were set in 2022, including two new all-time annual record lows in net sea-ice extent and area in February. Across the world’s oceans, global mean sea level was record high for the 11th consecutive year, reaching 101.2 mm above the 1993 average when satellite altimetry measurements began, an increase of 3.3±0.7 over 2021. Globally-averaged ocean heat content was also record high in 2022, while the global sea-surface temperature was the sixth highest on record, equal with 2018. Approximately 58% of the ocean surface experienced at least one marine heatwave in 2022. In the Bay of Plenty, New Zealand’s longest continuous marine heatwave was recorded. A total of 85 named tropical storms were observed during the Northern and Southern Hemisphere storm seasons, close to the 1991–2020 average of 87. There were three Category 5 tropical cyclones across the globe—two in the western North Pacific and one in the North Atlantic. This was the fewest Category 5 storms globally since 2017. Globally, the accumulated cyclone energy was the lowest since reliable records began in 1981. Regardless, some storms caused massive damage. In the North Atlantic, Hurricane Fiona became the most intense and most destructive tropical or post-tropical cyclone in Atlantic Canada’s history, while major Hurricane Ian killed more than 100 people and became the third costliest disaster in the United States, causing damage estimated at $113 billion U.S. dollars. In the South Indian Ocean, Tropical Cyclone Batsirai dropped 2044 mm of rain at Commerson Crater in Réunion. The storm also impacted Madagascar, where 121 fatalities were reported. As is typical, some areas around the world were notably dry in 2022 and some were notably wet. In August, record high areas of land across the globe (6.2%) were experiencing extreme drought. Overall, 29% of land experienced moderate or worse categories of drought during the year. The largest drought footprint in the contiguous United States since 2012 (63%) was observed in late October. The record-breaking megadrought of central Chile continued in its 13th consecutive year, and 80-year record-low river levels in northern Argentina and Paraguay disrupted fluvial transport. In China, the Yangtze River reached record-low values. Much of equatorial eastern Africa had five consecutive below-normal rainy seasons by the end of 2022, with some areas receiving record-low precipitation totals for the year. This ongoing 2.5-year drought is the most extensive and persistent drought event in decades, and led to crop failure, millions of livestock deaths, water scarcity, and inflated prices for staple food items. In South Asia, Pakistan received around three times its normal volume of monsoon precipitation in August, with some regions receiving up to eight times their expected monthly totals. Resulting floods affected over 30 million people, caused over 1700 fatalities, led to major crop and property losses, and was recorded as one of the world’s costliest natural disasters of all time. Near Rio de Janeiro, Brazil, Petrópolis received 530 mm in 24 hours on 15 February, about 2.5 times the monthly February average, leading to the worst disaster in the city since 1931 with over 230 fatalities. On 14–15 January, the Hunga Tonga-Hunga Ha'apai submarine volcano in the South Pacific erupted multiple times. The injection of water into the atmosphere was unprecedented in both magnitude—far exceeding any previous values in the 17-year satellite record—and altitude as it penetrated into the mesosphere. The amount of water injected into the stratosphere is estimated to be 146±5 Terragrams, or ∼10% of the total amount in the stratosphere. It may take several years for the water plume to dissipate, and it is currently unknown whether this eruption will have any long-term climate effect.
    Type of Medium: Online Resource
    ISSN: 0003-0007 , 1520-0477
    Language: Unknown
    Publisher: American Meteorological Society
    Publication Date: 2023
    detail.hit.zdb_id: 2029396-3
    detail.hit.zdb_id: 419957-1
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  • 2
    In: Advanced Science, Wiley, Vol. 4, No. 10 ( 2017-10)
    Abstract: This study has designed and implemented a library of hetero‐nanostructured catalysts, denoted as Pd@Nb 2 O 5 , comprised of size‐controlled Pd nanocrystals interfaced with Nb 2 O 5 nanorods. This study also demonstrates that the catalytic activity and selectivity of CO 2 reduction to CO and CH 4 products can be systematically tailored by varying the size of the Pd nanocrystals supported on the Nb 2 O 5 nanorods. Using large Pd nanocrystals, this study achieves CO and CH 4 production rates as high as 0.75 and 0.11 mol h −1 g Pd −1 , respectively. By contrast, using small Pd nanocrystals, a CO production rate surpassing 18.8 mol h −1 g Pd −1 is observed with 99.5% CO selectivity. These performance metrics establish a new milestone in the champion league of catalytic nanomaterials that can enable solar‐powered gas‐phase heterogeneous CO 2 reduction. The remarkable control over the catalytic performance of Pd@Nb 2 O 5 is demonstrated to stem from a combination of photothermal, electronic and size effects, which is rationally tunable through nanochemistry.
    Type of Medium: Online Resource
    ISSN: 2198-3844 , 2198-3844
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2808093-2
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  • 3
    In: The American Journal of Human Genetics, Elsevier BV, Vol. 108, No. 2 ( 2021-02), p. 337-345
    Type of Medium: Online Resource
    ISSN: 0002-9297
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 1473813-2
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Informa UK Limited ; 2017
    In:  Energy Sources, Part A: Recovery, Utilization, and Environmental Effects Vol. 39, No. 3 ( 2017-02-01), p. 277-283
    In: Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, Informa UK Limited, Vol. 39, No. 3 ( 2017-02-01), p. 277-283
    Type of Medium: Online Resource
    ISSN: 1556-7036 , 1556-7230
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2238587-3
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  • 5
    In: Advanced Science, Wiley, Vol. 4, No. 10 ( 2017-10)
    Type of Medium: Online Resource
    ISSN: 2198-3844 , 2198-3844
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2808093-2
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  • 6
    In: Journal of Energy Storage, Elsevier BV, Vol. 62 ( 2023-06), p. 106855-
    Type of Medium: Online Resource
    ISSN: 2352-152X
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2826805-2
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  • 7
    In: Advanced Sustainable Systems, Wiley, Vol. 1, No. 11 ( 2017-11)
    Type of Medium: Online Resource
    ISSN: 2366-7486 , 2366-7486
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2880982-8
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  • 8
    Online Resource
    Online Resource
    Wiley ; 2017
    In:  Advanced Sustainable Systems Vol. 1, No. 11 ( 2017-11)
    In: Advanced Sustainable Systems, Wiley, Vol. 1, No. 11 ( 2017-11)
    Abstract: More than 20 gigatonnes of carbon dioxide are released into the atmosphere every year. The conversion of CO 2 into value‐added chemicals and fuels by solar energy is an immediate solution to mitigate CO 2 emissions, while providing global energy security. In this work, boron‐ and phosphorus‐doped silicon nanocrystals (ncSi), comprised of three earth‐abundant elements, are investigated for gas‐phase heterogeneous photoreduction of CO 2 for the first time. Surface dopants are demonstrated to induce CO 2 adsorption capacity. Remarkably, phosphorus‐doped ncSi is found to be the best performer among the singly doped and co‐doped ncSi samples, doubling the rate of pristine ncSi. The enhancement of activity is attributed to the combination of the number of surface hydrides, its surface hydrophobicity, the addition of electronegative surface atoms, and perhaps an enhanced hydridic character of the SiH induced by the n‐doping effect. Significantly, boron and phosphorus dopants are shown to provide increased stability of CO 2 reduction activity compared to pristine ncSi after storing the samples in air for 2 weeks. These noteworthy findings open up a pathway to develop sustainable alternatives for existing photocatalysts for CO 2 conversion.
    Type of Medium: Online Resource
    ISSN: 2366-7486 , 2366-7486
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2880982-8
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  • 9
    In: The Journal of Gene Medicine, Wiley
    Abstract: Multiple myeloma (MM) is a malignancy in which plasma cells proliferate abnormally, and it remains incurable. The cells are characterized by high levels of endoplasmic reticulum stress (ERS) and depend on the ERS response for survival. Thus, we aim to find an ERS‐related signature of MM and assess its diagnostic value. Methods We downloaded three datasets of MM from the Gene Expression Omnibus database. After identifying ERS‐related differentially expressed genes (ERDEGs), we analyzed them using Gene Ontology enrichment analysis. A protein–protein interaction network, a transcription factor–mRNA network, a miRNA–mRNA network and a drug–mRNA network were constructed to explore the ERDEGs. The clinical application of these genes was identified by calculating the infiltration of immune cells and using receiver operating characteistic analyses. Finally, qPCR was performed to further confirm the roles of ERDEGs. Results We obtained nine ERDEGs of MM. Gene Ontology enrichment indicated that the ERDEGs played a role in the endoplasmic reticulum membrane. Additionally, the protein–protein interaction network showed interaction among the ERDEGs, and there were 20 proteins, 107 transcription factors, 42 drugs or molecular compounds and 51 miRNAs which were likely to interact with the nine genes. In addition, immune cell infiltration analyses showed that there was a strong correlation between the nine genes and immune cells, and these potential biomarkers exhibited good diagnostic values. Finally, the expression of ERDEGs in MM cells was different from that in healthy donor samples. Conclusion The nine ERS‐related genes, CR2, DHCR7, DNAJC3, KDELR2, LPL, OSBPL3, PINK1, VCAM1 and XBP1 are potential biomarkers of MM, and this supports further clinical development of the diagnosis and treatment of MM.
    Type of Medium: Online Resource
    ISSN: 1099-498X , 1521-2254
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2002203-7
    SSG: 12
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  • 10
    In: Cellular & Molecular Immunology, Springer Science and Business Media LLC, Vol. 19, No. 5 ( 2022-03-10), p. 577-587
    Abstract: Neutrophil extracellular traps (NETs) can capture and kill viruses, such as influenza viruses, human immunodeficiency virus (HIV), and respiratory syncytial virus (RSV), thus contributing to host defense. Contrary to our expectation, we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2, as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model. The histone H3 or H4 selectively binds to subunit 2 of the spike (S) protein, as shown by a biochemical binding assay, surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids. Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein. Moreover, histones enhance cell–cell fusion. Finally, treatment with an inhibitor of NETosis, histone H3 or H4, or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model. These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19.
    Type of Medium: Online Resource
    ISSN: 2042-0226
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2219471-X
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