In:
Lipids, Wiley, Vol. 36, No. 12 ( 2001-12), p. 1327-1329
Abstract:
To assess the oxidative metabolism of conjugated linoleic acid (CLA) isomers, rats were force‐fed 1.5–2.6 MBq of [1‐ 14 C]‐linoleic acid (9 c ,12 c ‐18∶2),‐rumenic acid (9 c ,11 t ‐18∶2), or‐10 trans , 12 cis ‐18∶2 (10 t , 12 c ‐18∶2), and 14 CO 2 production was monitored for 24 h. The animals were then necropsied and the radioactivity determined in different tissues. Both CLA isomers were oxidized significantly more than linoleic acid. Moreover, less radioactivity was recovered in most tissues after CLA intake than after linoleic acid intake. The substantial oxidation of CLA isomers must be considered when assessing the putative health benefits of CLA supplements.
Type of Medium:
Online Resource
ISSN:
0024-4201
,
1558-9307
DOI:
10.1007/s11745-001-0848-8
Language:
English
Publisher:
Wiley
Publication Date:
2001
detail.hit.zdb_id:
2030265-4
SSG:
12
Bookmarklink