In:
Catheterization and Cardiovascular Interventions, Wiley, Vol. 76, No. 7 ( 2010-12), p. 986-992
Abstract:
Objectives : To determine immediate and long‐term clinical outcome, as well prognostic factors in patients who underwent repeat percutaneous mitral balloon valvuloplasty (PMBV). Background : Repeat PMBV may be a method of treatment for symptomatic patients with restenosis after successful initial PMBV, but data regarding its long term safety and efficacy are scarce. Methods : The study group consisted of 67 patients (mean age 52.1 ± 10.5 years). All PMBV procedures were performed using the Inoue balloon system. Results : Repeat PMBV resulted in significant increase in MVA from 1.17 ± 0.16 cm 2 to 1.63 ± 0.22 cm 2 ( P 〈 0.001). Good immediate result (MVA ≥1.5 cm 2 , mitral regurgitation ≤2) was obtained in 52 (77.6%) patients and was not predicted by any analyzed factors. During follow‐up (mean time 4.9 ± 2.9 years) six patients died, nine underwent mitral valve replacement, four—third PMBV, and four developed heart failure. The 3‐, 5‐, and 8‐year good functional results (survival free of mitral valve replacement, third PMBV or heart failure ≥ NYHA III) by Kaplan–Meier estimates were 89.3, 75.6, and 52.6%, respectively. These results were significantly superior in patients with good immediate results and echo score 〈 7. In the entire population multivariate Cox regression analysis identified echo score 〈 7 and absence of prior surgical commissurotomy as the independent predictors of event‐free survival. Conclusions : Repeat PMBV is safe and provides good immediate results in patients with restenosis after successful first procedure. Long‐term results of repeat PMBV are satisfactory and related mainly to the echo score and quality of the procedure. © 2010 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
1522-1946
,
1522-726X
Language:
English
Publisher:
Wiley
Publication Date:
2010
detail.hit.zdb_id:
2001555-0
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