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Assessment of Still and Moving Images in the Diagnosis of Gastric Lesions Using Magnifying Narrow-Band Imaging in a Prospective Multicenter Trial

Hayashi, Tomoyuki ; Doyama, Hisashi ; Shirota, Yukihiro ; [et al.]

Public Library of Science (PLoS) ; 2014

In: PLoS ONE Vol. 9, No. 7 ( 2014-7-2), p. e100857-

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In: PLoS ONE, Public Library of Science (PLoS), Vol. 9, No. 7 ( 2014-7-2), p. e100857-

Type of Medium: Online Resource

ISSN: 1932-6203

URL: Article

DOI: 10.1371/journal.pone.0100857

DOI: 10.1371/journal.pone.0100857.g001

DOI: 10.1371/journal.pone.0100857.g002

DOI: 10.1371/journal.pone.0100857.g003

DOI: 10.1371/journal.pone.0100857.g004

DOI: 10.1371/journal.pone.0100857.t001

DOI: 10.1371/journal.pone.0100857.t002

DOI: 10.1371/journal.pone.0100857.t003

DOI: 10.1371/journal.pone.0100857.t004

DOI: 10.1371/journal.pone.0100857.t005

DOI: 10.1371/journal.pone.0100857.t006

DOI: 10.1371/journal.pone.0100857.t007

DOI: 10.1371/journal.pone.0100857.s001

DOI: 10.1371/journal.pone.0100857.s002

DOI: 10.1371/journal.pone.0100857.s003

DOI: 10.1371/journal.pone.0100857.s004

DOI: 10.1371/journal.pone.0100857.s005

DOI: 10.1371/journal.pone.0100857.s006

DOI: 10.1371/journal.pone.0100857.s007

DOI: 10.1371/journal.pone.0100857.s008

DOI: 10.1371/journal.pone.0100857.s009

DOI: 10.1371/journal.pone.0100857.s010

DOI: 10.1371/journal.pone.0100857.s011

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2014

detail.hit.zdb_id: 2267670-3

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Visualization and quantification of the atrioventricular conduction axis in hearts with ventricular septal defect using phase contrast computed tomography

Yoshitake, Shuichi ; Kaneko, Yukihiro ; Morita, Kiyozo ; [et al.]

Elsevier BV ; 2020

In: The Journal of Thoracic and Cardiovascular Surgery Vol. 160, No. 2 ( 2020-08), p. 490-496

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In: The Journal of Thoracic and Cardiovascular Surgery, Elsevier BV, Vol. 160, No. 2 ( 2020-08), p. 490-496

Type of Medium: Online Resource

ISSN: 0022-5223

URL: Article

DOI: 10.1016/j.jtcvs.2020.02.036

Language: English

Publisher: Elsevier BV

Publication Date: 2020

detail.hit.zdb_id: 2007600-9

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GARFIELD-AF: risk profiles, treatment patterns and 2-year outcomes in patients with atrial fibrillation in Germany, Austria and Switzerland (DACH) compared to 32 countries in other regions worldwide

Haas, Sylvia ; Camm, John A. ; Harald, Darius ; [et al.]

Springer Science and Business Media LLC ; 2023

In: Clinical Research in Cardiology Vol. 112, No. 6 ( 2023-06), p. 759-771

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In: Clinical Research in Cardiology, Springer Science and Business Media LLC, Vol. 112, No. 6 ( 2023-06), p. 759-771

Type of Medium: Online Resource

ISSN: 1861-0684 , 1861-0692

URL: Article

DOI: 10.1007/s00392-022-02079-y

RVK:

XA 37040

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2023

detail.hit.zdb_id: 2218331-0

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5th Japanese Association of Hepato-Biliary-Pancreatic Surgery : October 14?15, 1993, Arcadia Ichigaya, Tokyo, Japan President: Fujio Hanyu

Miyazaki, Kohji ; Tsutsumi, Nobuo ; Kitahara, Kenji ; [et al.]

Springer Science and Business Media LLC ; 1993

In: Journal of Hepato-Biliary-Pancreatic Surgery Vol. 1, No. 1 ( 1993-2), p. 42-104

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In: Journal of Hepato-Biliary-Pancreatic Surgery, Springer Science and Business Media LLC, Vol. 1, No. 1 ( 1993-2), p. 42-104

Type of Medium: Online Resource

ISSN: 0944-1166 , 1436-0691

URL: Article

DOI: 10.1007/BF01235934

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 1993

detail.hit.zdb_id: 2536390-6

detail.hit.zdb_id: 1473162-9

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Factors Influencing Treatment Efficacy of 24-Week Combination Therapy with Interferon α-2b Plus Ribavirin for Chronic Hepatitis C

Moriyama, Mitsuhiko ; Matsumura, Hiroshi ; Nirei, Kazushige ; [et al.]

Springer Science and Business Media LLC ; 2007

In: Digestive Diseases and Sciences Vol. 52, No. 9 ( 2007-8-7), p. 2418-2426

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In: Digestive Diseases and Sciences, Springer Science and Business Media LLC, Vol. 52, No. 9 ( 2007-8-7), p. 2418-2426

Type of Medium: Online Resource

ISSN: 0163-2116 , 1573-2568

URL: Article

DOI: 10.1007/s10620-006-9693-0

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2007

detail.hit.zdb_id: 2015102-0

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Serum levels of soluble interferon alfa/beta receptor as an inhibitory factor of interferon in the patients with chronic hepatitis C

Mizukoshi, Eishiro ; Kaneko, Shuichi ; Kaji, Kyosuke ; [et al.]

Ovid Technologies (Wolters Kluwer Health) ; 1999

In: Hepatology Vol. 30, No. 5 ( 1999-11), p. 1325-1331

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In: Hepatology, Ovid Technologies (Wolters Kluwer Health), Vol. 30, No. 5 ( 1999-11), p. 1325-1331

Type of Medium: Online Resource

ISSN: 0270-9139 , 1527-3350

URL: Issue

URL: Journal

URL: Article

DOI: 10.1002/hep.v30:5

DOI: 10.1002/(ISSN)1527-3350

DOI: 10.1002/hep.510300516

Language: English

Publisher: Ovid Technologies (Wolters Kluwer Health)

Publication Date: 1999

detail.hit.zdb_id: 1472120-X

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Optimal uric acid levels by febuxostat treatment and cerebral, cardiorenovascular risks: post hoc analysis of a randomized controlled trial

Kojima, Sunao ; Uchiyama, Kazuaki ; Yokota, Naoto ; [et al.]

Oxford University Press (OUP) ; 2022

In: Rheumatology Vol. 61, No. 6 ( 2022-05-30), p. 2346-2359

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In: Rheumatology, Oxford University Press (OUP), Vol. 61, No. 6 ( 2022-05-30), p. 2346-2359

Abstract: Hyperuricaemia is recognized as an independent risk marker for cardiovascular and renal diseases. However, uric acid is a powerful free-radical scavenger, and the optimal level of serum uric acid (SUA) determining outcomes is unknown. This study explored whether interventional treatments for excessive SUA reduction were harmful and what constituted the optimal lowering of SUA levels for the prevention of events in patients with asymptomatic hyperuricaemia. Methods This was a post hoc analysis of a randomized trial (Febuxostat for Cerebral and CaRdiorenovascular Events PrEvEntion StuDy [FREED]) in which 1070 older patients with asymptomatic hyperuricaemia were enrolled and allocated to febuxostat (n = 537) or non-febuxostat treatment group (n = 533). We assessed the relationship between the endpoint (withdrawal or study completion) SUA levels and clinical outcomes. Primary endpoint was defined as a composite of all-cause mortality, cerebral and cardiorenovascular events. Results In the febuxostat group, patients achieving SUA levels ≤4 mg/dl (hazard ratio: 2.01 [95% CI: 1.05, 3.87]), & gt;4 to ≤5 mg/dl (2.12 [1.07, 4.20], & gt;6 to ≤7 mg/dl (2.42 [1.05, 5.60]), and & gt;7 mg/dl (4.73 [2.13, 10.5]) had significantly higher risks for a primary composite event than those achieving SUA levels & gt;5 to ≤6 mg/dl (P = 0.003 [log-rank test]). This J-shaped relationship applied to patients with renal impairment (P = 0.007 [Gray’s test] ) and was not significant in the non-febuxostat treatment group (P = 0.212 [log-rank test]). Conclusion Optimal SUA level by febuxostat treatment is 5–6 mg/dl for reducing all-cause mortality, cerebral, cardiovascular and renal events. Excessive SUA reduction may be harmful in older hyperuricaemic populations. Trial Registration ClinicalTrial.gov, https://clinicaltrials.gov, NCT01984749

Type of Medium: Online Resource

ISSN: 1462-0324 , 1462-0332

URL: Article

DOI: 10.1093/rheumatology/keab739

Language: English

Publisher: Oxford University Press (OUP)

Publication Date: 2022

detail.hit.zdb_id: 1474143-X

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Evaluation of a new histologic staging and grading system for primary biliary cirrhosis in comparison with classical systems

Kakuda, Yuko ; Harada, Kenichi ; Sawada-Kitamura, Seiko ; [et al.]

Elsevier BV ; 2013

In: Human Pathology Vol. 44, No. 6 ( 2013-6), p. 1107-1117

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In: Human Pathology, Elsevier BV, Vol. 44, No. 6 ( 2013-6), p. 1107-1117

Type of Medium: Online Resource

ISSN: 0046-8177

URL: Article

DOI: 10.1016/j.humpath.2012.09.017

RVK:

XA 10000

Language: English

Publisher: Elsevier BV

Publication Date: 2013

detail.hit.zdb_id: 2041481-X

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Rhythmic Messenger Ribonucleic Acid Expression of Clock Genes and Adipocytokines in Mouse Visceral Adipose Tissue

Ando, Hitoshi ; Yanagihara, Hayato ; Hayashi, Yohei ; [et al.]

The Endocrine Society ; 2005

In: Endocrinology Vol. 146, No. 12 ( 2005-12-01), p. 5631-5636

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In: Endocrinology, The Endocrine Society, Vol. 146, No. 12 ( 2005-12-01), p. 5631-5636

Abstract: Various peripheral tissues show circadian rhythmicity, which is generated at the cellular level by their own core oscillators that are composed of transcriptional/translational feedback loops involving a set of clock genes. Although the circulating levels of some adipocytokines, i.e. bioactive substances secreted by adipocytes, are on a 24-h rhythmic cycle, it remains to be elucidated whether the clock gene system works in adipose tissue. To address this issue, we investigated the daily mRNA expression profiles of the clock genes and adipocytokines in mouse perigonadal adipose tissues. In C57BL/6J mice, all transcript levels of the clock genes (Bmal1, Per1, Per2, Cry1, Cry2, and Dbp) and adipocytokines (adiponectin, resistin, and visfatin) clearly showed 24-h rhythms. On the other hand, the rhythmic expression of these genes was mildly attenuated in obese KK mice and greatly attenuated in more obese, diabetic KK-Ay mice. Obese diabetes also diminished the rhythmic expression of the clock genes in the liver. Interestingly, a 2-wk treatment of KK and KK-Ay mice with pioglitazone impaired the 24-h rhythmicity of the mRNA expression of the clock genes and adipocytokines despite the antidiabetic effect of the drug. In contrast, pioglitazone improved the attenuated rhythmicity in the liver. These findings suggest that the intracellular clock gene system acts in visceral adipose tissues as well as liver and is influenced by the conditions of obesity/type 2 diabetes and pioglitazone treatment.

Type of Medium: Online Resource

ISSN: 0013-7227 , 1945-7170

URL: Article

DOI: 10.1210/en.2005-0771

Language: English

Publisher: The Endocrine Society

Publication Date: 2005

detail.hit.zdb_id: 2011695-0

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Identification of the atrioventricular conduction axis and its positional relationship with anatomical landmarks of a heart with tricuspid atresia

Wada, Yuson ; Matsuhisa, Hironori ; Oshima, Yoshihiro ; [et al.]

Elsevier BV ; 2021

In: JTCVS Open Vol. 8 ( 2021-12), p. 557-560

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In: JTCVS Open, Elsevier BV, Vol. 8 ( 2021-12), p. 557-560

Type of Medium: Online Resource

ISSN: 2666-2736

URL: Article

DOI: 10.1016/j.xjon.2021.09.048

Language: English

Publisher: Elsevier BV

Publication Date: 2021

detail.hit.zdb_id: 3028409-0

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