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Operation and performance of the ATLAS semiconductor tracker in LHC Run 2

Aad, Georges ; Abbott, Brad ; Abbott, Dale Charles ; [et al.]

IOP Publishing ; 2022

In: Journal of Instrumentation Vol. 17, No. 01 ( 2022-01-01), p. P01013-

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In: Journal of Instrumentation, IOP Publishing, Vol. 17, No. 01 ( 2022-01-01), p. P01013-

Abstract: The semiconductor tracker (SCT) is one of the tracking systems for charged particles in the ATLAS detector. It consists of 4088 silicon strip sensor modules. During Run 2 (2015–2018) the Large Hadron Collider delivered an integrated luminosity of 156 fb -1 to the ATLAS experiment at a centre-of-mass proton-proton collision energy of 13 TeV. The instantaneous luminosity and pile-up conditions were far in excess of those assumed in the original design of the SCT detector. Due to improvements to the data acquisition system, the SCT operated stably throughout Run 2. It was available for 99.9% of the integrated luminosity and achieved a data-quality efficiency of 99.85%. Detailed studies have been made of the leakage current in SCT modules and the evolution of the full depletion voltage, which are used to study the impact of radiation damage to the modules.

Type of Medium: Online Resource

ISSN: 1748-0221

URL: Article

DOI: 10.1088/1748-0221/17/01/P01013

Language: Unknown

Publisher: IOP Publishing

Publication Date: 2022

detail.hit.zdb_id: 2235672-1

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Experimental, numerical and theoretical investigations of Tesla turbines

Klingl, Stefan ; Lecheler, Stefan ; Pfitzner, Michael ; [et al.]

EDP Sciences ; 2019

In: E3S Web of Conferences Vol. 113 ( 2019), p. 03003-

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In: E3S Web of Conferences, EDP Sciences, Vol. 113 ( 2019), p. 03003-

Abstract: We use analytical, numerical and experimental methods to characterize the laminar flow inside a Tesla turbine rotor gap. A comparison based on one particular set of operating conditions mutually validates the three approaches. The simplicity of the analytical flow model allows for a cost efficient optimization of the underlying turbine parameters. Performance charts exhibit general trends and serve as a guide for preliminary turbine design and optimization. In terms of the ratio of half the gap width to inlet radius and the ratio of outletto inlet radius, the designer of a tesla turbine has to find a compromise between optimal efficiency and optimal power output.

Type of Medium: Online Resource

ISSN: 2267-1242

URL: Article

DOI: 10.1051/e3sconf/201911303003

Language: English

Publisher: EDP Sciences

Publication Date: 2019

detail.hit.zdb_id: 2755680-3

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A novel Methylomirabilota methanotroph potentially couples methane oxidation to iodate reduction

Zhu, Baoli ; Karwautz, Clemens ; Andrei, Stefan ; [et al.]

Wiley ; 2022

In: mLife Vol. 1, No. 3 ( 2022-09), p. 323-328

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In: mLife, Wiley, Vol. 1, No. 3 ( 2022-09), p. 323-328

Abstract: Methane oxidizing microbes play a key role in reducing the emission of this potent greenhouse gas to the atmosphere. The known versatility of the recently discovered anaerobic Methylomirabilota methanotrophs is limited. Here, we report a novel uncultured Methylomirabilis species, Candidatus Methylomirabilis iodofontis , with the genetic potential of iodate respiration from biofilm in iodine‐rich cavern spring water. Star‐like cells resembling Methylomirabilis oxyfera were directly observed from the biofilm and a high‐quality metagenome‐assembled genome (MAG) of Ca . M. iodofontis was assembled. In addition to oxygenic denitrification and aerobic methane oxidation pathways, the M. iodofontis MAG also indicated its iodate‐reducing potential, a capability that would enable the bacterium to use iodate other than nitrite as an electron acceptor, a hitherto unrecognized metabolic potential of Methylomirabilota methanotrophs. The results advance the current understanding of the ecophysiology of anaerobic Methylomirabilota methanotrophs and may suggest an additional methane sink, especially in iodate‐rich ecosystems.

Type of Medium: Online Resource

ISSN: 2770-100X , 2770-100X

URL: Issue

URL: Article

DOI: 10.1002/mlf2.v1.3

DOI: 10.1002/mlf2.12033

Language: English

Publisher: Wiley

Publication Date: 2022

detail.hit.zdb_id: 3120417-X

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Reinterpretation of LHC Results for New Physics: Status and recommendations after Run 2

Abdallah, Waleed ; Salam, Shehu Abdus ; Ahmadov, Azar ; [et al.]

Stichting SciPost ; 2020

In: SciPost Physics Vol. 9, No. 2 ( 2020-08-21)

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In: SciPost Physics, Stichting SciPost, Vol. 9, No. 2 ( 2020-08-21)

Abstract: We report on the status of efforts to improve the reinterpretation of searches and measurements at the LHC in terms of models for new physics, in the context of the LHC Reinterpretation Forum. We detail current experimental offerings in direct searches for new particles, measurements, technical implementations and Open Data, and provide a set of recommendations for further improving the presentation of LHC results in order to better enable reinterpretation in the future. We also provide a brief description of existing software reinterpretation frameworks and recent global analyses of new physics that make use of the current data.

Type of Medium: Online Resource

ISSN: 2542-4653

URL: Journal

URL: Article

DOI: 10.21468/SciPostPhys

DOI: 10.21468/SciPostPhys.9.2.022

Language: Unknown

Publisher: Stichting SciPost

Publication Date: 2020

detail.hit.zdb_id: 2886659-9

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Fibroblast Growth Factor 2‐Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons

Kumar, Rohit ; Tang, Qilin ; Müller, Stephan A. ; [et al.]

Wiley ; 2020

In: Advanced Science Vol. 7, No. 6 ( 2020-03)

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In: Advanced Science, Wiley, Vol. 7, No. 6 ( 2020-03)

Abstract: Extracellular vesicles (EVs) are endogenous membrane‐derived vesicles that shuttle bioactive molecules between glia and neurons, thereby promoting neuronal survival and plasticity in the central nervous system (CNS) and contributing to neurodegenerative conditions. Although EVs hold great potential as CNS theranostic nanocarriers, the specific molecular factors that regulate neuronal EV uptake and release are currently unknown. A combination of patch‐clamp electrophysiology and pH‐sensitive dye imaging is used to examine stimulus‐evoked EV release in individual neurons in real time. Whereas spontaneous electrical activity and the application of a high‐frequency stimulus induce a slow and prolonged fusion of multivesicular bodies (MVBs) with the plasma membrane (PM) in a subset of cells, the neurotrophic factor basic fibroblast growth factor (bFGF) greatly increases the rate of stimulus‐evoked MVB‐PM fusion events and, consequently, the abundance of EVs in the culture medium. Proteomic analysis of neuronal EVs demonstrates bFGF increases the abundance of the v‐SNARE vesicle‐associated membrane protein 3 (VAMP3, cellubrevin) on EVs. Conversely, knocking‐down VAMP3 in cultured neurons attenuates the effect of bFGF on EV release. The results determine the temporal characteristics of MVB‐PM fusion in hippocampal neurons and reveal a new function for bFGF signaling in controlling neuronal EV release.

Type of Medium: Online Resource

ISSN: 2198-3844 , 2198-3844

URL: Issue

URL: Article

DOI: 10.1002/advs.v7.6

DOI: 10.1002/advs.201902372

Language: English

Publisher: Wiley

Publication Date: 2020

detail.hit.zdb_id: 2808093-2

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Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions

Scherer, Myriam ; Klingl, Stefan ; Sevvana, Madhumati ; [et al.]

Public Library of Science (PLoS) ; 2014

In: PLoS Pathogens Vol. 10, No. 11 ( 2014-11-20), p. e1004512-

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In: PLoS Pathogens, Public Library of Science (PLoS), Vol. 10, No. 11 ( 2014-11-20), p. e1004512-

Type of Medium: Online Resource

ISSN: 1553-7374

URL: Article

DOI: 10.1371/journal.ppat.1004512

DOI: 10.1371/journal.ppat.1004512.g001

DOI: 10.1371/journal.ppat.1004512.g002

DOI: 10.1371/journal.ppat.1004512.g003

DOI: 10.1371/journal.ppat.1004512.g004

DOI: 10.1371/journal.ppat.1004512.g005

DOI: 10.1371/journal.ppat.1004512.g006

DOI: 10.1371/journal.ppat.1004512.g007

DOI: 10.1371/journal.ppat.1004512.g008

DOI: 10.1371/journal.ppat.1004512.s001

DOI: 10.1371/journal.ppat.1004512.s002

DOI: 10.1371/journal.ppat.1004512.s003

DOI: 10.1371/journal.ppat.1004512.s004

DOI: 10.1371/journal.ppat.1004512.s005

DOI: 10.1371/journal.ppat.1004512.s006

DOI: 10.1371/journal.ppat.1004512.s007

DOI: 10.1371/journal.ppat.1004512.s008

DOI: 10.1371/journal.ppat.1004512.s009

DOI: 10.1371/journal.ppat.1004512.s010

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2014

detail.hit.zdb_id: 2205412-1

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Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica

Peters, Britta ; Stein, Johanna ; Klingl, Stefan ; [et al.]

Public Library of Science (PLoS) ; 2017

In: PLOS Pathogens Vol. 13, No. 5 ( 2017-5-30), p. e1006418-

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In: PLOS Pathogens, Public Library of Science (PLoS), Vol. 13, No. 5 ( 2017-5-30), p. e1006418-

Type of Medium: Online Resource

ISSN: 1553-7374

URL: Article

DOI: 10.1371/journal.ppat.1006418

DOI: 10.1371/journal.ppat.1006418.g001

DOI: 10.1371/journal.ppat.1006418.g002

DOI: 10.1371/journal.ppat.1006418.g003

DOI: 10.1371/journal.ppat.1006418.g004

DOI: 10.1371/journal.ppat.1006418.g005

DOI: 10.1371/journal.ppat.1006418.g006

DOI: 10.1371/journal.ppat.1006418.g007

DOI: 10.1371/journal.ppat.1006418.g008

DOI: 10.1371/journal.ppat.1006418.g009

DOI: 10.1371/journal.ppat.1006418.t001

DOI: 10.1371/journal.ppat.1006418.t002

DOI: 10.1371/journal.ppat.1006418.s001

DOI: 10.1371/journal.ppat.1006418.s002

DOI: 10.1371/journal.ppat.1006418.s003

DOI: 10.1371/journal.ppat.1006418.s004

DOI: 10.1371/journal.ppat.1006418.s005

DOI: 10.1371/journal.ppat.1006418.s006

DOI: 10.1371/journal.ppat.1006418.s007

DOI: 10.1371/journal.ppat.1006418.s008

DOI: 10.1371/journal.ppat.1006418.s009

DOI: 10.1371/journal.ppat.1006418.s010

DOI: 10.1371/journal.ppat.1006418.s011

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2017

detail.hit.zdb_id: 2205412-1

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Recombinant protein production and purification of SiiD, SiiE and SiiF - Components of the SPI4-encoded type I secretion system from Salmonella Typhimurium

Klingl, Stefan ; Kordes, Sina ; Schmid, Benedikt ; [et al.]

Elsevier BV ; 2020

In: Protein Expression and Purification Vol. 172 ( 2020-08), p. 105632-

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In: Protein Expression and Purification, Elsevier BV, Vol. 172 ( 2020-08), p. 105632-

Type of Medium: Online Resource

ISSN: 1046-5928

URL: Article

DOI: 10.1016/j.pep.2020.105632

Language: English

Publisher: Elsevier BV

Publication Date: 2020

detail.hit.zdb_id: 1471688-4

SSG: 12

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The Central Vacuole of the Diatom Phaeodactylum tricornutum : Identification of New Vacuolar Membrane Proteins and of a Functional Di-leucine-based Targeting Motif

Schreiber, Viktoria ; Dersch, Josefine ; Puzik, Katharina ; [et al.]

Elsevier BV ; 2017

In: Protist Vol. 168, No. 3 ( 2017-07), p. 271-282

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In: Protist, Elsevier BV, Vol. 168, No. 3 ( 2017-07), p. 271-282

Type of Medium: Online Resource

ISSN: 1434-4610

URL: Article

DOI: 10.1016/j.protis.2017.03.001

Language: English

Publisher: Elsevier BV

Publication Date: 2017

detail.hit.zdb_id: 1419415-6

detail.hit.zdb_id: 2036014-9

detail.hit.zdb_id: 3033701-X

SSG: 12

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Manipulation of charge distribution in the arginine and glutamate clusters of the OmpG pore alters sugar specificity and ion selectivity

Schmitt, Christine ; Bafna, Jayesh Arun ; Schmid, Benedikt ; [et al.]

Elsevier BV ; 2019

In: Biochimica et Biophysica Acta (BBA) - Biomembranes Vol. 1861, No. 10 ( 2019-10), p. 183021-

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In: Biochimica et Biophysica Acta (BBA) - Biomembranes, Elsevier BV, Vol. 1861, No. 10 ( 2019-10), p. 183021-

Type of Medium: Online Resource

ISSN: 0005-2736

URL: Article

DOI: 10.1016/j.bbamem.2019.07.009

RVK:

WA 15000

Language: English

Publisher: Elsevier BV

Publication Date: 2019

detail.hit.zdb_id: 2209384-9

SSG: 12

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