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  • 1
    In: GeroScience, Springer Science and Business Media LLC, Vol. 44, No. 3 ( 2022-06), p. 1641-1655
    Abstract: Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)
    Type of Medium: Online Resource
    ISSN: 2509-2715 , 2509-2723
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2886418-9
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  • 2
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2007
    In:  ACM Transactions on Database Systems Vol. 32, No. 2 ( 2007-06), p. 8-
    In: ACM Transactions on Database Systems, Association for Computing Machinery (ACM), Vol. 32, No. 2 ( 2007-06), p. 8-
    Abstract: A common problem in many types of databases is retrieving the most similar matches to a query object. Finding these matches in a large database can be too slow to be practical, especially in domains where objects are compared using computationally expensive similarity (or distance) measures. Embedding methods can significantly speed-up retrieval by mapping objects into a vector space, where distances can be measured rapidly using a Minkowski metric. In this article we present a novel way to improve embedding quality. In particular, we propose to construct embeddings that use a query-sensitive distance measure for the target space of the embedding. This distance measure is used to compare those vectors that the query and database objects are mapped to. The term “query-sensitive” means that the distance measure changes, depending on the current query object. We demonstrate theoretically that using a query-sensitive distance measure increases the modeling power of embeddings and allows them to capture more of the structure of the original space. We also demonstrate experimentally that query-sensitive embeddings can significantly improve retrieval performance. In experiments with an image database of handwritten digits and a time-series database, the proposed method outperforms existing state-of-the-art non-Euclidean indexing methods, meaning that it provides significantly better tradeoffs between efficiency and retrieval accuracy.
    Type of Medium: Online Resource
    ISSN: 0362-5915 , 1557-4644
    RVK:
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2007
    detail.hit.zdb_id: 196155-X
    detail.hit.zdb_id: 2006335-0
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  • 3
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2009
    In:  ACM Transactions on Database Systems Vol. 34, No. 1 ( 2009-04), p. 1-35
    In: ACM Transactions on Database Systems, Association for Computing Machinery (ACM), Vol. 34, No. 1 ( 2009-04), p. 1-35
    Abstract: In the emerging area of sensor-based systems, a significant challenge is to develop scalable, fault-tolerant methods to extract useful information from the data the sensors collect. An approach to this data management problem is the use of sensor database systems, which allow users to perform aggregation queries such as MIN, COUNT, and AVG on the readings of a sensor network. In addition, more advanced queries such as frequency counting and quantile estimation can be supported. Due to energy limitations in sensor-based networks, centralized data collection is generally impractical, so most systems use in-network aggregation to reduce network traffic. However, even these aggregation strategies remain bandwidth-intensive when combined with the fault-tolerant, multipath routing methods often used in these environments. To avoid this expense, we investigate the use of approximate in-network aggregation using small sketches. We present duplicate-insensitive sketching techniques that can be implemented efficiently on small sensor devices with limited hardware support and we analyze both their performance and accuracy. Finally, we present an experimental evaluation that validates the effectiveness of our methods.
    Type of Medium: Online Resource
    ISSN: 0362-5915 , 1557-4644
    RVK:
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2009
    detail.hit.zdb_id: 196155-X
    detail.hit.zdb_id: 2006335-0
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  • 4
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2009
    In:  Knowledge and Information Systems Vol. 21, No. 2 ( 2009-11), p. 133-171
    In: Knowledge and Information Systems, Springer Science and Business Media LLC, Vol. 21, No. 2 ( 2009-11), p. 133-171
    Type of Medium: Online Resource
    ISSN: 0219-1377 , 0219-3116
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2009
    detail.hit.zdb_id: 2023541-0
    detail.hit.zdb_id: 2036569-X
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  • 5
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2014
    In:  ACM Transactions on Database Systems Vol. 39, No. 2 ( 2014-05), p. 1-46
    In: ACM Transactions on Database Systems, Association for Computing Machinery (ACM), Vol. 39, No. 2 ( 2014-05), p. 1-46
    Abstract: Large-scale data analysis lies in the core of modern enterprises and scientific research. With the emergence of cloud computing, the use of an analytical query processing infrastructure can be directly associated with monetary cost. MapReduce has been a popular framework in the context of cloud computing, designed to serve long-running queries (jobs) which can be processed in batch mode. Taking into account that different jobs often perform similar work, there are many opportunities for sharing. In principle, sharing similar work reduces the overall amount of work, which can lead to reducing monetary charges for utilizing the processing infrastructure. In this article we present a sharing framework tailored to MapReduce, namely, 〈 tt 〉 MRShare 〈 /tt 〉 . Our framework, 〈 tt 〉 MRShare 〈 /tt 〉 , transforms a batch of queries into a new batch that will be executed more efficiently, by merging jobs into groups and evaluating each group as a single query. Based on our cost model for MapReduce, we define an optimization problem and we provide a solution that derives the optimal grouping of queries. Given the query grouping, we merge jobs appropriately and submit them to MapReduce for processing. A key property of 〈 tt 〉 MRShare 〈 /tt 〉 is that it is independent of the MapReduce implementation. Experiments with our prototype, built on top of Hadoop, demonstrate the overall effectiveness of our approach. 〈 tt 〉 MRShare 〈 /tt 〉 is primarily designed for handling I/O-intensive queries. However, with the development of high-level languages operating on top of MapReduce, user queries executed in this model become more complex and CPU intensive. Commonly, executed queries can be modeled as evaluating pipelines of CPU-expensive filters over the input stream. Examples of such filters include, but are not limited to, index probes, or certain types of joins. In this article we adapt some of the standard techniques for filter ordering used in relational and stream databases, propose their extensions, and implement them through 〈 tt 〉 MRAdaptiveFilter 〈 /tt 〉 , an extension of 〈 tt 〉 MRShare 〈 /tt 〉 for expensive filter ordering tailored to MapReduce, which allows one to handle both single- and batch-query execution modes. We present an experimental evaluation that demonstrates additional benefits of 〈 tt 〉 MRAdaptiveFilter 〈 /tt 〉 , when executing CPU-intensive queries in 〈 tt 〉 MRShare 〈 /tt 〉 .
    Type of Medium: Online Resource
    ISSN: 0362-5915 , 1557-4644
    RVK:
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2014
    detail.hit.zdb_id: 196155-X
    detail.hit.zdb_id: 2006335-0
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  • 6
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2000
    In:  ACM SIGMOD Record Vol. 29, No. 2 ( 2000-06), p. 463-474
    In: ACM SIGMOD Record, Association for Computing Machinery (ACM), Vol. 29, No. 2 ( 2000-06), p. 463-474
    Abstract: Finding approximate answers to multi-dimensional range queries over real valued attributes has significant applications in data exploration and database query optimization. In this paper we consider the following problem: given a table of d attributes whose domain is the real numbers, and a query that specifies a range in each dimension, find a good approximation of the number of records in the table that satisfy the query. We present a new histogram technique that is designed to approximate the density of multi-dimensional datasets with real attributes. Our technique finds buckets of variable size, and allows the buckets to overlap. Overlapping buckets allow more efficient approximation of the density. The size of the cells is based on the local density of the data. This technique leads to a faster and more compact approximation of the data distribution. We also show how to generalize kernel density estimators, and how to apply them on the multi-dimensional query approximation problem. Finally, we compare the accuracy of the proposed techniques with existing techniques using real and synthetic datasets.
    Type of Medium: Online Resource
    ISSN: 0163-5808
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2000
    detail.hit.zdb_id: 243829-X
    detail.hit.zdb_id: 2051432-3
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  • 7
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2012
    In:  Proceedings of the VLDB Endowment Vol. 5, No. 11 ( 2012-07), p. 1579-1590
    In: Proceedings of the VLDB Endowment, Association for Computing Machinery (ACM), Vol. 5, No. 11 ( 2012-07), p. 1579-1590
    Abstract: This paper proposes a general framework for matching similar subsequences in both time series and string databases. The matching results are pairs of query subsequences and database subsequences. The framework finds all possible pairs of similar subsequences if the distance measure satisfies the "consistency" property, which is a property introduced in this paper. We show that most popular distance functions, such as the Euclidean distance, DTW, ERP, the Frechét distance for time series, and the Hamming distance and Levenshtein distance for strings, are all "consistent". We also propose a generic index structure for metric spaces named "reference net". The reference net occupies O ( n ) space, where n is the size of the dataset and is optimized to work well with our framework. The experiments demonstrate the ability of our method to improve retrieval performance when combined with diverse distance measures. The experiments also illustrate that the reference net scales well in terms of space overhead and query time.
    Type of Medium: Online Resource
    ISSN: 2150-8097
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2012
    detail.hit.zdb_id: 2478691-3
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  • 8
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2012
    In:  Proceedings of the VLDB Endowment Vol. 5, No. 12 ( 2012-08), p. 1930-1933
    In: Proceedings of the VLDB Endowment, Association for Computing Machinery (ACM), Vol. 5, No. 12 ( 2012-08), p. 1930-1933
    Abstract: We present "Hum-a-song", a system built for music retrieval, and particularly for the Query-By-Humming (QBH) application. According to QBH, the user is able to hum a part of a song that she recalls and would like to learn what this song is, or find other songs similar to it in a large music repository. We present a simple yet efficient approach that maps the problem to time series subsequence matching. The query and the database songs are represented as 2-dimensional time series conveying information about the pitch and the duration of the notes. Then, since the query is a short sequence and we want to find its best match that may start and end anywhere in the database, subsequence matching methods are suitable for this task. In this demo, we present a system that employs and exposes to the user a variety of state-of-the-art dynamic programming methods, including a newly proposed efficient method named SMBGT that is robust to noise and considers all intrinsic problems in QBH; it allows variable tolerance levels when matching elements, where tolerances are defined as functions of the compared sequences, gaps in both the query and target sequences, and bounds the matching length and (optionally) the minimum number of matched elements. Our system is intended to become open source, which is to the best of our knowledge the first non-commercial effort trying to solve QBH with a variety of methods, and that also approaches the problem from the time series perspective.
    Type of Medium: Online Resource
    ISSN: 2150-8097
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2012
    detail.hit.zdb_id: 2478691-3
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  • 9
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2005
    In:  The VLDB Journal Vol. 14, No. 2 ( 2005-04), p. 137-154
    In: The VLDB Journal, Springer Science and Business Media LLC, Vol. 14, No. 2 ( 2005-04), p. 137-154
    Type of Medium: Online Resource
    ISSN: 1066-8888 , 0949-877X
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2005
    detail.hit.zdb_id: 1463009-6
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  • 10
    Online Resource
    Online Resource
    Association for Computing Machinery (ACM) ; 2009
    In:  Proceedings of the VLDB Endowment Vol. 2, No. 1 ( 2009-08), p. 205-216
    In: Proceedings of the VLDB Endowment, Association for Computing Machinery (ACM), Vol. 2, No. 1 ( 2009-08), p. 205-216
    Abstract: This paper introduces a novel method, called Reference-Based String Alignment (RBSA), that speeds up retrieval of optimal subsequence matches in large databases of sequences under the edit distance and the Smith-Waterman similarity measure. RBSA operates using the assumption that the optimal match deviates by a relatively small amount from the query, an amount that does not exceed a prespecified fraction of the query length. RBSA has an exact version that guarantees no false dismissals and can handle large queries efficiently. An approximate version of RBSA is also described, that achieves significant additional improvements over the exact version, with negligible losses in retrieval accuracy. RBSA performs filtering of candidate matches using precomputed alignment scores between the database sequence and a set of fixed-length reference sequences. At query time, the query sequence is partitioned into segments of length equal to that of the reference sequences. For each of those segments, the alignment scores between the segment and the reference sequences are used to efficiently identify a relatively small number of candidate subsequence matches. An alphabet collapsing technique is employed to improve the pruning power of the filter step. In our experimental evaluation, RBSA significantly outperforms state-of-the-art biological sequence alignment methods, such as q-grams, BLAST, and BWT.
    Type of Medium: Online Resource
    ISSN: 2150-8097
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2009
    detail.hit.zdb_id: 2478691-3
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