In:
Molecular Informatics, Wiley, Vol. 35, No. 8-9 ( 2016-09), p. 326-332
Abstract:
A novel class of antibacterial and antifungal agents is here identified by means of dockings and virtual screening techniques. Biological data proved the initial effort, formulated on the structure similarity of nuclear receptors binders with known quinolones or thiazole derivatives, to reposition PPARs agonists as likely bacterial type II topoisomerases inhibitors.
Type of Medium:
Online Resource
ISSN:
1868-1743
,
1868-1751
DOI:
10.1002/minf.v35.8-9
DOI:
10.1002/minf.201600021
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2537668-8
SSG:
15,3
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