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Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study

Charlier, Caroline ; Perrodeau, Élodie ; Leclercq, Alexandre ; [et al.]

Elsevier BV ; 2017

In: The Lancet Infectious Diseases Vol. 17, No. 5 ( 2017-05), p. 510-519

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In: The Lancet Infectious Diseases, Elsevier BV, Vol. 17, No. 5 ( 2017-05), p. 510-519

Type of Medium: Online Resource

ISSN: 1473-3099

URL: Article

DOI: 10.1016/S1473-3099(16)30521-7

Language: English

Publisher: Elsevier BV

Publication Date: 2017

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Prognostic value of KRAS mutations in stage III colon cancer: post hoc analysis of the PETACC8 phase III trial dataset

Thaler, Josef ; Greil, Richard ; Gaenzer, Johannes ; [et al.]

Elsevier BV ; 2015

In: Annals of Oncology Vol. 26, No. 4 ( 2015-04), p. 822-825

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In: Annals of Oncology, Elsevier BV, Vol. 26, No. 4 ( 2015-04), p. 822-825

Type of Medium: Online Resource

ISSN: 0923-7534

URL: Article

DOI: 10.1093/annonc/mdv070

Language: English

Publisher: Elsevier BV

Publication Date: 2015

detail.hit.zdb_id: 2003498-2

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Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming

Hickey, Raymond D. ; Galivo, Feorillo ; Schug, Jonathan ; [et al.]

Elsevier BV ; 2013

In: Stem Cell Research Vol. 11, No. 1 ( 2013-07), p. 503-515

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In: Stem Cell Research, Elsevier BV, Vol. 11, No. 1 ( 2013-07), p. 503-515

Type of Medium: Online Resource

ISSN: 1873-5061

URL: Article

DOI: 10.1016/j.scr.2013.02.005

Language: English

Publisher: Elsevier BV

Publication Date: 2013

detail.hit.zdb_id: 2393143-7

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Mice Defective in Two Apoptosis Pathways in the Myeloid Lineage Develop Acute Myeloblastic Leukemia

Traver, David ; Akashi, Koichi ; Weissman, Irving L. ; [et al.]

Elsevier BV ; 1998

In: Immunity Vol. 9, No. 1 ( 1998-07), p. 47-57

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In: Immunity, Elsevier BV, Vol. 9, No. 1 ( 1998-07), p. 47-57

Type of Medium: Online Resource

ISSN: 1074-7613

URL: Article

DOI: 10.1016/S1074-7613(00)80587-7

RVK:

XA 48754.8

Language: English

Publisher: Elsevier BV

Publication Date: 1998

detail.hit.zdb_id: 2001966-X

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Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1

Francipane, Maria Giovanna ; Lagasse, Eric

Impact Journals, LLC ; 2013

In: Oncotarget Vol. 4, No. 11 ( 2013-11-30), p. 1948-1962

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In: Oncotarget, Impact Journals, LLC, Vol. 4, No. 11 ( 2013-11-30), p. 1948-1962

Type of Medium: Online Resource

ISSN: 1949-2553

URL: Issue

URL: Article

DOI: 10.18632/oncotarget.v4i11

DOI: 10.18632/oncotarget.1310

Language: English

Publisher: Impact Journals, LLC

Publication Date: 2013

detail.hit.zdb_id: 2560162-3

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Beyond 'Natural': Cigarette Ad Tactics that Mislead about Relative Risk

Moran, Meghan Bridgid ; Brown, Jennifer ; Lindblom, Eric ; [et al.]

Auricle Technologies, Pvt., Ltd. ; 2018

In: Tobacco Regulatory Science Vol. 4, No. 5 ( 2018-09-01), p. 3-19

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In: Tobacco Regulatory Science, Auricle Technologies, Pvt., Ltd., Vol. 4, No. 5 ( 2018-09-01), p. 3-19

Type of Medium: Online Resource

ISSN: 2333-9748

URL: Article

DOI: 10.18001/TRS.4.5.1

Language: English

Publisher: Auricle Technologies, Pvt., Ltd.

Publication Date: 2018

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BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

Omidvar, Nader ; Kogan, Scott ; Beurlet, Stephanie ; [et al.]

American Association for Cancer Research (AACR) ; 2007

In: Cancer Research Vol. 67, No. 24 ( 2007-12-15), p. 11657-11667

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In: Cancer Research, American Association for Cancer Research (AACR), Vol. 67, No. 24 ( 2007-12-15), p. 11657-11667

Abstract: Myelodysplastic syndromes (MDS) are clonal stem cell hematologic disorders that evolve to acute myeloid leukemia (AML) and thus model multistep leukemogenesis. Activating RAS mutations and overexpression of BCL-2 are prognostic features of MDS/AML transformation. Using NRASD12 and BCL-2, we created two distinct models of MDS and AML, where human (h)BCL-2 is conditionally or constitutively expressed. Our novel transplantable in vivo models show that expression of hBCL-2 in a primitive compartment by mouse mammary tumor virus–long terminal repeat results in a disease resembling human MDS, whereas the myeloid MRP8 promoter induces a disease with characteristics of human AML. Expanded leukemic stem cell (Lin−/Sca-1+/c-Kit+) populations and hBCL-2 in the increased RAS-GTP complex within the expanded Sca-1+ compartment are described in both MDS/AML–like diseases. Furthermore, the oncogenic compartmentalizations provide the proapoptotic versus antiapoptotic mechanisms, by activating extracellular signal-regulated kinase and AKT signaling, in determination of the neoplastic phenotype. When hBCL-2 is switched off with doxycycline in the MDS mice, partial reversal of the phenotype was observed with persistence of bone marrow blasts and tissue infiltration as RAS recruits endogenous mouse (m)BCL-2 to remain active, thus demonstrating the role of the complex in the disease. This represents the first in vivo progression model of MDS/AML dependent on the formation of a BCL-2:RAS-GTP complex. The colocalization of BCL-2 and RAS in the bone marrow of MDS/AML patients offers targeting either oncogene as a therapeutic strategy. [Cancer Res 2007;67(24):11657–67]

Type of Medium: Online Resource

ISSN: 0008-5472 , 1538-7445

URL: Article

DOI: 10.1158/0008-5472.CAN-07-0196

RVK:

XA 36000

RVK:

XA 10000

Language: English

Publisher: American Association for Cancer Research (AACR)

Publication Date: 2007

detail.hit.zdb_id: 2036785-5

detail.hit.zdb_id: 1432-1

detail.hit.zdb_id: 410466-3

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Kinetics of Liver Repopulation after Bone Marrow Transplantation

Wang, Xin ; Montini, Eugenio ; Al-Dhalimy, Muhsen ; [et al.]

Elsevier BV ; 2002

In: The American Journal of Pathology Vol. 161, No. 2 ( 2002-08), p. 565-574

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In: The American Journal of Pathology, Elsevier BV, Vol. 161, No. 2 ( 2002-08), p. 565-574

Type of Medium: Online Resource

ISSN: 0002-9440

URL: Article

DOI: 10.1016/S0002-9440(10)64212-5

RVK:

XA 10000

RVK:

XA 19800

Language: English

Publisher: Elsevier BV

Publication Date: 2002

detail.hit.zdb_id: 1480207-7

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Liver Repopulation and Correction of Metabolic Liver Disease by Transplanted Adult Mouse Pancreatic Cells

Wang, Xin ; Al-Dhalimy, Muhsen ; Lagasse, Eric ; [et al.]

Elsevier BV ; 2001

In: The American Journal of Pathology Vol. 158, No. 2 ( 2001-02), p. 571-579

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In: The American Journal of Pathology, Elsevier BV, Vol. 158, No. 2 ( 2001-02), p. 571-579

Type of Medium: Online Resource

ISSN: 0002-9440

URL: Article

DOI: 10.1016/S0002-9440(10)63999-5

RVK:

XA 10000

RVK:

XA 19800

Language: English

Publisher: Elsevier BV

Publication Date: 2001

detail.hit.zdb_id: 1480207-7

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Distinct Human Stem Cell Populations in Small and Large Intestine

Cramer, Julie M. ; Thompson, Timothy ; Geskin, Albert ; [et al.]

Public Library of Science (PLoS) ; 2015

In: PLOS ONE Vol. 10, No. 3 ( 2015-3-9), p. e0118792-

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In: PLOS ONE, Public Library of Science (PLoS), Vol. 10, No. 3 ( 2015-3-9), p. e0118792-

Type of Medium: Online Resource

ISSN: 1932-6203

URL: Article

DOI: 10.1371/journal.pone.0118792

DOI: 10.1371/journal.pone.0118792.g001

DOI: 10.1371/journal.pone.0118792.g002

DOI: 10.1371/journal.pone.0118792.g003

DOI: 10.1371/journal.pone.0118792.g004

DOI: 10.1371/journal.pone.0118792.g005

DOI: 10.1371/journal.pone.0118792.g006

DOI: 10.1371/journal.pone.0118792.t001

DOI: 10.1371/journal.pone.0118792.s001

DOI: 10.1371/journal.pone.0118792.s002

DOI: 10.1371/journal.pone.0118792.s003

DOI: 10.1371/journal.pone.0118792.s004

DOI: 10.1371/journal.pone.0118792.s005

DOI: 10.1371/journal.pone.0118792.s006

DOI: 10.1371/journal.pone.0118792.s007

DOI: 10.1371/journal.pone.0118792.s008

DOI: 10.1371/journal.pone.0118792.s009

DOI: 10.1371/journal.pone.0118792.s010

DOI: 10.1371/journal.pone.0118792.s011

DOI: 10.1371/journal.pone.0118792.s012

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2015

detail.hit.zdb_id: 2267670-3

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