In:
Journal of Medical Virology, Wiley, Vol. 81, No. 4 ( 2009-04), p. 573-577
Abstract:
Travel influences the spread of non‐B subtypes of HIV in Europe. The aim of this study was to assess whether the spread of non‐B subtypes occurred in Croatia, a country with a low level HIV infection. Phylogenetic analysis of the reverse transcriptase and protease genes was undertaken in 145 Croatian patients with the following risks for HIV‐infection: men who have sex with men (n = 64), heterosexual contact (n = 54), intravenous drug use (n = 21), bisexual contact (n = 4) and intravenous drug use plus heterosexual exposure (n = 2). The sample included 25 seamen and 13 steady female sexual partners of seamen. Overall, 38 (26%) of HIV‐patients were infected with non‐B subtypes. Non‐B subtype infections were found only in patients with a possible heterosexual exposure. Non‐B infections were most frequent in seamen and their regular female partners (in 27 of 38 seamen and their partners, 71%). The relative distribution of non‐B subtypes was as follows: A, 8%; C, 26%; F, 3%; CRF01_AE, 8%; CRF02_AG, 34%; CRF05_DF, 5%; CRF06_cpx, 3%; CRF10_CD 8%; and subtype U, 5%. There were altogether 19 heterosexual couples, phylogenetic analysis confirmed that the paired samples were related in all cases. Non‐B subtypes were found only in individuals with a heterosexual risk, mainly in seamen and their partners. J. Med. Virol. 81:573–577, 2009 © 2009 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
0146-6615
,
1096-9071
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
752392-0
detail.hit.zdb_id:
1475090-9
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