In:
International Psychogeriatrics, Cambridge University Press (CUP), Vol. 24, No. S1 ( 2012-08), p. S21-S24
Abstract:
Neuroplasticity, the ability of synapses to undergo structural adaptations in response to functional demand or dysfunctions is increasingly impaired in aging and Alzheimer's disease. EGb761 ® has been shown in several preclinical reports to increase nearly all aspects of impaired neuroplasticity (long-term potentiation, spine density, neuritogenesis, neurogenesis). While all three fractions of constituents (ginkgolides, flavonoids, bilobalide) seem to be active, the flavonoids and specifically the aglycone isorhamnetin seem to be most relevant.
Type of Medium:
Online Resource
ISSN:
1041-6102
,
1741-203X
DOI:
10.1017/S1041610212000592
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
2012
detail.hit.zdb_id:
2147136-8
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