In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 1 ( 2023-1-26), p. e0269096-
Abstract:
This study evaluated short-term (1-month) and long-term (1-year) mortality risks associated with the glomerular filtration rate (eGFR) on admission for patients with intracerebral hemorrhage. Methods From the Taiwan Stroke Registry data from April 2006 to December 2016, we identified and stratified patients with intracerebral hemorrhage into five subgroups by the eGFR level on admission: ≥90, 60–89, 30–59, 15–29, and 〈 15 mL/min/1.73 m 2 or on dialysis. Risks for 1-month and 1-year mortality after intracerebral hemorrhage were compared by the eGFR levels. Results Both the 1-month and 1-year mortality rates progressively increased with the decrease in eGFR levels. The 1-month mortality rate in patients with eGFR 〈 15 mL/min/1.73 m 2 or on dialysis was approximately 5.5-fold greater than that in patients with eGFR ≥ 90 mL/min/1.73 m 2 (8.31 versus 1.50 per 1000 person-days), with an adjusted hazard ratio (HR) of 4.59 [95% confidence interval (CI) = 2.71–7.78]. Similarly, the 1-year mortality in patients with eGFR 〈 15 mL/min/1.73 m 2 or on dialysis was 7.5 times that in patients with eGFR ≥ 90 mL/min/1.73 m 2 (2.34 versus 0.31 per 1000 person-days), with an adjusted HR of 4.54 (95% CI 2.95–6.98). Conclusion Impairment of renal function is an independent risk factor for mortality in patients with intracerebral hemorrhage in a gradual way. The eGFR level is a prognostic indicator for patients with intracerebral hemorrhage.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0269096
DOI:
10.1371/journal.pone.0269096.g001
DOI:
10.1371/journal.pone.0269096.g002
DOI:
10.1371/journal.pone.0269096.g003
DOI:
10.1371/journal.pone.0269096.t001
DOI:
10.1371/journal.pone.0269096.t002
DOI:
10.1371/journal.pone.0269096.t003
DOI:
10.1371/journal.pone.0269096.t004
DOI:
10.1371/journal.pone.0269096.t005
DOI:
10.1371/journal.pone.0269096.s001
DOI:
10.1371/journal.pone.0269096.s002
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3
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