In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 2 ( 2022-2-16), p. e0263894-
Abstract:
The predictive value of non-invasive electrocardiographic examination findings for the risk of sudden cardiac death (SCD) in populations with structurally normal hearts remains unclear. This study aimed to investigate the characteristics of the QRS vectorcardiography of surface electrocardiography in patients with structurally normal hearts who experienced SCD. We consecutively enrolled patients who underwent vectorcardiography between March 2017 and December 2018 in a tertiary referral medical center. These patients didn’t have structural heart diseases, histories of congestive heart failure, or reduced ejection fraction, and they were classified into SCD (with aborted SCD history and cerebral performance category score of 1) and control groups (with an intervention for atrioventricular node reentrant tachycardia and without SCD history). A total of 162 patients (mean age, 54.3±18.1 years; men, 75.9%), including 59 in the SCD group and 103 in the control group, underwent propensity analysis. The baseline demographic variables, underlying diseases, QRS loop descriptors (the percentage of the loop area, loop dispersion, and inter-lead QRS dispersion), and other electrocardiographic parameters were compared between the two groups. In the univariate and multivariate analyses, a smaller percentage of the loop area (odds ratio, 0.0003; 95% confidence interval, 0.00–0.02; p 〈 0.001), more significant V 4-5 dispersion (odds ratio, 1.04; 95% confidence interval, 1.02–1.07; p = 0.002), and longer QRS duration (odds ratio, 1.05; 95% confidence interval, 1.00–1.10; p = 0.04) were associated with SCD. In conclusion, the QRS loop descriptors of surface electrocardiography could be used as non-invasive markers to identify patients experiencing aborted SCD from a healthy population. A decreased percentage of loop area and elevated V 4-5 QRS dispersion values assessed using vectorcardiography were associated with an increased risk of SCD in patients with structurally normal hearts.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0263894
DOI:
10.1371/journal.pone.0263894.g001
DOI:
10.1371/journal.pone.0263894.g002
DOI:
10.1371/journal.pone.0263894.g003
DOI:
10.1371/journal.pone.0263894.g004
DOI:
10.1371/journal.pone.0263894.t001
DOI:
10.1371/journal.pone.0263894.t002
DOI:
10.1371/journal.pone.0263894.t003
DOI:
10.1371/journal.pone.0263894.s001
DOI:
10.1371/journal.pone.0263894.s002
DOI:
10.1371/journal.pone.0263894.s003
DOI:
10.1371/journal.pone.0263894.s004
DOI:
10.1371/journal.pone.0263894.s005
DOI:
10.1371/journal.pone.0263894.s006
DOI:
10.1371/journal.pone.0263894.s007
DOI:
10.1371/journal.pone.0263894.s008
DOI:
10.1371/journal.pone.0263894.r001
DOI:
10.1371/journal.pone.0263894.r002
DOI:
10.1371/journal.pone.0263894.r003
DOI:
10.1371/journal.pone.0263894.r004
DOI:
10.1371/journal.pone.0263894.r005
DOI:
10.1371/journal.pone.0263894.r006
DOI:
10.1371/journal.pone.0263894.r007
DOI:
10.1371/journal.pone.0263894.r008
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2267670-3
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