In:
Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 98, No. 51 ( 2019-12), p. e18188-
Abstract:
We compared the effects of 50% N 2 O and N 2 O titration in burn management to alleviate pain and anxiety associated with burn dressing. Methods: In this single-blind prospective randomized controlled trial, 70 stable adult burn patients were randomized to 2 groups during May 2015 to January 2016. The experimental group was titrated with N 2 O ranging from 30% to the ideal sedation concentration before dressing change until the end. The control group was treated with 50% N 2 O 2 minutes before dressing change until the end. Pain, anxiety, vital signs, and the highest concentrations of N 2 O inhaled were recorded at 1 minute before N 2 O inhalation (T0), dismantling of outer (T1), inner dressings (T2), debridement (T3), drug-smearing (T4), bandaging (T5), and 10 minutes after completion of the procedure (T6). Results: The pain and anxiety scores in the experimental group performed significantly less than the control group during T2-T6. The systolic blood pressure in T2 and the heart rate at T2 and T3 varied significantly between the 2 groups. The highest N 2 O concentrations of the experimental group were mainly 60% to 70% at T2 (87.9%), T3 (87.9%), and T4 (81.8%). Conclusion: N 2 O titration significantly reduced pain and anxiety in burn patients, with minimal side effects.
Type of Medium:
Online Resource
ISSN:
0025-7974
,
1536-5964
DOI:
10.1097/MD.0000000000018188
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2019
detail.hit.zdb_id:
2049818-4
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