In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 139, No. Suppl_1 ( 2019-03-05)
Abstract:
Introduction: Family history (FH) is a well-known risk factor for cardiovascular disease (CVD); however, the association of FH with CVD in Hispanic/Latino populations has not been well investigated. We examined the cross-sectional association of FH of CVD or CVD risk factors with individual CVD risk factors (hypertension, hypercholesterolemia, obesity, diabetes mellitus, and smoking), CVD risk profile, and prevalence of CHD or stroke in the HCHS/SOL. Methods: Baseline data on FH and CVD risk factors from 15,104 HCHS/SOL participants were analyzed. Self-reported first-degree FH of high blood pressure (BP), high cholesterol, diabetes, angina, heart attack, heart failure, rheumatic heart disease, angioplasty/bypass, stroke, aortic aneurysm, and peripheral artery disease was ascertained and categorized as any first-degree FH vs. no FH of each condition. Hypertension, high cholesterol, obesity and diabetes mellitus were ascertained by objective measures and/or medication use; smoking was self-reported. The CVD risk profile was calculated by assigning a score of 0 to 5 based on the number of adverse CVD risk factors. Analysis of CVD risk factors was dichotomized as low (0 and 1 risk factor) vs. high (2+ risk factors). Odds ratios and 95% confidence intervals were derived from logistic regression models, accounting for the complex study design and controlling for multiple covariates. Results: Prevalence of CVD risk factors and risk profile were associated with self-reported FH (see Table). Furthermore, prevalence of CHD was associated with FH of high BP, high cholesterol, diabetes, angina, heart attack, heart failure, and rheumatic heart disease. Personal history of stroke was associated with FH of high BP, angina, and aortic aneurysm. Conclusions: First-degree FH of CVD factors and diseases was associated with hypertension, high cholesterol, obesity, diabetes, CHD and stroke among Hispanics/Latinos in HCHS/SOL. Ascertainment of FH should be an integral part of CVD risk assessment in Hispanics/Latinos in the US.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.139.suppl_1.P372
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2019
detail.hit.zdb_id:
1466401-X
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