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  • 1
    In: Autophagy, Informa UK Limited, Vol. 17, No. 1 ( 2021-01-02), p. 1-382
    Type of Medium: Online Resource
    ISSN: 1554-8627 , 1554-8635
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2262043-6
    SSG: 12
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  • 2
    In: Autophagy, Informa UK Limited, Vol. 12, No. 1 ( 2016-01-02), p. 1-222
    Type of Medium: Online Resource
    ISSN: 1554-8627 , 1554-8635
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2262043-6
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Frontiers Media SA ; 2023
    In:  Frontiers in Public Health Vol. 11 ( 2023-6-13)
    In: Frontiers in Public Health, Frontiers Media SA, Vol. 11 ( 2023-6-13)
    Abstract: Vaccination as a fundamental pillar of promoting public health and interest is critical to limiting the COVID-19 pandemic. However, many citizens are still hesitant about this epidemic prevention measure. This article aimed to understand the COVID-19 vaccination and hesitancy rates among Guangzhou residents at different points in time as well as to explore the relevant factors that cause vaccination hesitancy. Methods We conducted a total of nine cross-sectional surveys by enrolling 12,977 questionnaires among Guangzhou residents through the online survey software called “WenJuanXing” between April 2021 and December 2022, and residents made their choices by judging their willingness to vaccinate. These surveys collected data on the participants' sociodemographic characteristics, vaccination status, vaccine hesitancy, and factors influencing this hesitancy. The Chi-squared test was used for univariate analysis and the multivariate logistic regression model was used to further adjust the influence of the confounding factors to evaluate the main factors affecting the hesitancy of the COVID-19 vaccine at different periods. Results Over the course of 2021–2022, a total of 12,977 residents in the study area were surveyed. The vaccine hesitancy rates fluctuated over time. From April to June 2021, the vaccine hesitancy rate decreased from 30% to 9.1% and then increased to 13.7% in November. However, from April to December 2022, the hesitancy rate continued to rise from 13.4% to 30.4%. Vaccination rates, the epidemic waves of COVID-19, and changes in policies may all be possible factors that contributed to these fluctuations in vaccine hesitancy rates. We found statistically significant correlations between factors, such as residence, education, and occupation, and vaccine hesitancy at certain points of time. The results of the surveys in April and June 2021 showed that rural residents showed higher vaccine hesitancy rate than urban residents. Their lower education level was associated with higher vaccine hesitancy. Workers and farmers are more likely to have vaccine hesitancy than people with other occupations. The univariate analysis showed that people with underlying medical conditions and lower perceived health status were more likely to experience vaccine hesitation. Logistic regression analysis revealed that the health status of individuals is the most important factor leading to vaccine hesitancy, and residents' underestimation of domestic risks and overconfidence in personal protection measures were also contributing factors. At different stages, vaccine hesitancy among residents was related to vaccine side effects, safety and efficacy, convenience fluctuation, and various factors. Conclusion In the present study, we found that vaccine hesitancy did not display a consistent downward trend but it fluctuated over time. Higher education, residing in urban areas, lower perceived disease risk, and concerns about the vaccine's safety and side effects were risk factors for vaccine hesitancy. Implementing appropriate interventions and educational programs tailored to address these risk factors may prove to be effective in enhancing public confidence on vaccination.
    Type of Medium: Online Resource
    ISSN: 2296-2565
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2711781-9
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  • 4
    In: Acta Physico-Chimica Sinica, Acta Physico-Chimica Sinica & University Chemistry Editorial Office, Peking University, Vol. 19, No. 12 ( 2003), p. 1102-1107
    Type of Medium: Online Resource
    ISSN: 1000-6818
    Language: English
    Publisher: Acta Physico-Chimica Sinica & University Chemistry Editorial Office, Peking University
    Publication Date: 2003
    detail.hit.zdb_id: 2474339-2
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  • 5
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2022
    In:  Acta Physica Sinica Vol. 0, No. 0 ( 2022), p. 0-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 0, No. 0 ( 2022), p. 0-
    Abstract: Potential energy curves (PECs), dipole moments (DMs) and transition dipole moments (TDMs) of the X〈sup〉2〈/sup〉Π, a〈sup〉4〈/sup〉Σ〈sup〉-〈/sup〉, A〈sup〉2〈/sup〉Σ〈sup〉-〈/sup〉, b〈sup〉4〈/sup〉Π, B〈sup〉2〈/sup〉ΣΔ, C〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉, D〈sup〉2〈/sup〉Π, 2〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉 states correlating with the three lowest dissociation channels of AsH〈sup〉+〈/sup〉cation are calculated by using the multireference configuration interaction (MRCI) method. The Davidson corrections, core-valence (CV) correlation and spin-orbit coupling (SOC) effects are considered. The aug-cc-pV5Z all-electron basis set of H atom and the aug-cc-pwCV5Z-PP pseudopotential basis set of As atom is selected in the calculation.〈br〉In the complete active space self-consistent field (CASSCF) calculation, H (1s) and As (4s4p) shell are selected as active orbital, As (3p3d) shells are selected as closed orbital, which keeps doubly occupation, the rest electrons are in the frozen orbital. In the MRCI calculation, As (3p3d) shells are used for CV correlation, the calculation accuracy can be improved. SOC effects are considered with Breit-Pauli operators.〈br〉All calculated states are bound states. The X〈sup〉2〈/sup〉Π is the ground state, which is a depth potential well, the dissociation energy is 3.100 eV. The b〈sup〉4〈/sup〉Π, C〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉 and D〈sup〉2〈/sup〉Π are weakly bound states. The spectroscopic parameters are obtained by solving radial Schrodinger equation. To the best of our knowledge, there have not any study on the spectroscopy of AsH〈sup〉+〈/sup〉 cation. Compared with Ⅴ-hydride cations MH〈sup〉+〈/sup〉 (M = N, P, As), the order of the energy levels of the low-lying states for three ions are same. The dissociation energy and harmonic frequency both decreases with increase the atomic weight of M.〈br〉At spin-free level, the PECs of b〈sup〉4〈/sup〉Π and B〈sup〉2〈/sup〉Δ states cross at about 1.70 Å. When SOC effects are taken into account, according to the rule of avoid-crossing, the 〈i〉B〈/i〉〈sup〉2〈/sup〉Δ〈sub〉3/2〈/sub〉 and 〈i〉B〈/i〉〈sup〉2〈/sup〉Δ〈sub〉5/2〈/sub〉 states change to the double potential wells, and the avoided crossing between the 〈i〉B〈/i〉〈sup〉2〈/sup〉Δ〈sub〉3/2〈/sub〉 (〈i〉B〈/i〉〈sup〉2〈/sup〉Δ〈sub〉3/2〈/sub〉) and 〈i〉b〈/i〉〈sup〉4〈/sup〉Π〈sub〉3/2〈/sub〉 (〈i〉b〈/i〉〈sup〉4〈/sup〉Π〈sub〉5/2〈/sub〉) states is observed, respectively. The transition dipole moments (TDMs) of the 〈i〉A〈/i〉〈sup〉2〈/sup〉Σ〈sup〉-〈/sup〉→〈i〉X〈/i〉〈sup〉2〈/sup〉Π,〈i〉a〈/i〉〈sup〉4〈/sup〉Σ〈sub〉1/2〈/sub〉〈sup〉-〈/sup〉,〈i〉X〈/i〉〈sup〉2〈/sup〉Π〈sub〉1/2〈/sub〉 and 〈i〉A〈/i〉〈sup〉2〈/sup〉Σ〈sub〉1/2〈/sub〉〈sup〉-〈/sup〉→〈i〉X〈/i〉〈sup〉2〈/sup〉Π〈sub〉1/2〈/sub〉 transitions are also calculated. The TDM at equilibrium distance of the 〈i〉a〈/i〉〈sup〉4〈/sup〉Σ〈sub〉1/2〈/sub〉〈sup〉-〈/sup〉→〈i〉X〈/i〉〈sup〉2〈/sup〉Π〈sub〉1/2〈/sub〉 spin-forbidden reaches 0.036 Debye, therefore, the SOC effect plays an important role. Based on the accurately PECs and PDMs, the Franck-Condon factors, spontaneous radiative coefficients and spontaneous radiative lifetimes of the 〈i〉A〈/i〉〈sup〉2〈/sup〉Σ〈sup〉-〈/sup〉→〈i〉X〈/i〉〈sup〉2〈/sup〉Π,〈i〉a〈/i〉〈sup〉4〈/sup〉Σ〈sub〉1/2〈/sub〉〈sup〉-〈/sup〉→和〈i〉X〈/i〉〈sup〉2〈/sup〉Π〈sub〉1/2〈/sub〉 and 〈i〉A〈/i〉〈sup〉2〈/sup〉Σ〈sub〉1/2〈/sub〉〈sup〉-〈/sup〉→〈i〉X〈/i〉〈sup〉2〈/sup〉Π〈sub〉1/2〈/sub〉 transitions are also calculated.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2022
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  • 6
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2022
    In:  Acta Physica Sinica Vol. 71, No. 21 ( 2022), p. 213101-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 71, No. 21 ( 2022), p. 213101-
    Abstract: 〈sec〉Potential energy curves (PECs), dipole moments (DMs) and transition dipole moments (TDMs) of the X〈sup〉2〈/sup〉Π, a〈sup〉4〈/sup〉Σ〈sup〉–〈/sup〉, A〈sup〉2〈/sup〉Σ〈sup〉–〈/sup〉, b〈sup〉4〈/sup〉Π, B〈sup〉2〈/sup〉Δ, C〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉, D〈sup〉2〈/sup〉Π, 2〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉 states correlating with the three lowest dissociation channels of AsH〈sup〉+〈/sup〉 cation are calculated by using the multireference configuration interaction (MRCI) method. The Davidson correction, core-valence (CV) correlation, and spin-orbit coupling (SOC) effect are all considered. The aug-cc-pV5Z all-electron basis set of H atom and the aug-cc-pwCV5Z-PP pseudopotential basis set of As atom are both selected in the calculation.〈/sec〉〈sec〉In the complete active space self-consistent field (CASSCF) calculation, H (1s) and As (4s4p) shell are selected as active orbitals, As (3p3d) shells are selected as closed orbitals, which keeps doubly occupation, the remaining electrons are in the frozen orbitals. In the MRCI calculation, As (3p3d) shells are used for CV correlation, and the calculation accuracy can be improved. The SOC effects are considered with Breit-Pauli operators.〈/sec〉〈sec〉All calculated states are bound states. The X〈sup〉2〈/sup〉Π is the ground state, which is a deep potential well, the dissociation energy is 3.100 eV. The b〈sup〉4〈/sup〉Π, C〈sup〉2〈/sup〉Σ〈sup〉+〈/sup〉 and D〈sup〉2〈/sup〉Π are weakly bound states. The spectroscopic parameters are obtained by solving radial Schrodinger equation. To the best of our knowledge, there has been no study of the spectroscopy of AsH〈sup〉+〈/sup〉 cation so far. Comparing with Ⅴ-hydride cations 〈i〉M〈/i〉H〈sup〉+〈/sup〉 (〈i〉M〈/i〉 = N, P, As), the orders of the energy levels of the low-lying states for three ions are identical. The dissociation energy and harmonic frequency both decrease with the increase of the atomic weight of 〈i〉M〈/i〉.〈/sec〉〈sec〉At spin-free level, the PEC of b〈sup〉4〈/sup〉Π state and the PEC of B〈sup〉2〈/sup〉Δ state cross at about 1.70 Å. When SOC effects are taken into account, according to the rule of avoid-crossing, the 〈inline-formula〉〈tex-math id="M5"〉\begin{document}$ {{{\rm{B}}^2}}{\Delta _{3/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M5.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M5.png"/〉〈/alternatives〉〈/inline-formula〉state and 〈inline-formula〉〈tex-math id="M6"〉\begin{document}$ {{{\rm{B}}^2}}{\Delta _{5/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M6.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M6.png"/〉〈/alternatives〉〈/inline-formula〉state change to the double potential wells, and the avoided crossing between the 〈inline-formula〉〈tex-math id="M7"〉\begin{document}$ {{{\rm{B}}^2}}{\Delta _{3/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M7.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M7.png"/〉〈/alternatives〉〈/inline-formula〉 (〈inline-formula〉〈tex-math id="M8"〉\begin{document}$ {{{\rm{B}}^2}}{\Delta _{3/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M8.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M8.png"/〉〈/alternatives〉〈/inline-formula〉) state and 〈inline-formula〉〈tex-math id="M9"〉\begin{document}${{\rm{b}}^4}{\Pi _{3/2}}$\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M9.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M9.png"/〉〈/alternatives〉〈/inline-formula〉 (〈inline-formula〉〈tex-math id="M10"〉\begin{document}${{\rm{b}}^4}{\Pi _{5/2}}$\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M10.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M10.png"/〉〈/alternatives〉〈/inline-formula〉) state is observed. The transition dipole moment (TDM) of the 〈inline-formula〉〈tex-math id="M11"〉\begin{document}$ {{{\rm{A}}^2}}{\Sigma ^ - } \to {{{\rm{X}}^2}}\Pi $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M11.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M11.png"/〉〈/alternatives〉〈/inline-formula〉, 〈inline-formula〉〈tex-math id="M12"〉\begin{document}$ {{{\rm{a}}^4}}\Sigma _{1/2}^ - \to {{{\rm{X}}^2}}{\Pi _{1/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M12.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M12.png"/〉〈/alternatives〉〈/inline-formula〉 and 〈inline-formula〉〈tex-math id="M13"〉\begin{document}$ {{{\rm{A}}^2}}\Sigma _{1/2}^ - \to {{{\rm{X}}^2}}{\Pi _{1/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M13.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M13.png"/〉〈/alternatives〉〈/inline-formula〉 transition are also calculated. The TDM at the equilibrium distance of the 〈inline-formula〉〈tex-math id="M14"〉\begin{document}$ {{{\rm{a}}^4}}\Sigma _{1/2}^ - \to {{{\rm{X}}^2}}{\Pi _{1/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M14.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M14.png"/〉〈/alternatives〉〈/inline-formula〉 spin-forbidden reaches 0.036 Debye, therefore, the SOC effect plays an important role. Based on the accurate PECs and PDMs, the Franck-Condon factors, spontaneous radiative coefficients, and spontaneous radiative lifetimes of the 〈inline-formula〉〈tex-math id="M15"〉\begin{document}$ {{{\rm{A}}^2}}{\Sigma ^ - } \to {{{\rm{X}}^2}}\Pi $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M15.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M15.png"/〉〈/alternatives〉〈/inline-formula〉, 〈inline-formula〉〈tex-math id="M16"〉\begin{document}$ {{{\rm{a}}^4}}\Sigma _{1/2}^ - \to {{{\rm{X}}^2}}{\Pi _{1/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M16.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M16.png"/〉〈/alternatives〉〈/inline-formula〉, and 〈inline-formula〉〈tex-math id="M17"〉\begin{document}$ {{{\rm{A}}^2}}\Sigma _{1/2}^ - \to {{{\rm{X}}^2}}{\Pi _{1/2}} $\end{document}〈/tex-math〉〈alternatives〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M17.jpg"/〉〈graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="21-20221104_M17.png"/〉〈/alternatives〉〈/inline-formula〉 transition are also calculated.〈/sec〉
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2022
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  • 7
    Online Resource
    Online Resource
    Elsevier BV ; 2021
    In:  Sensors and Actuators B: Chemical Vol. 343 ( 2021-09), p. 130060-
    In: Sensors and Actuators B: Chemical, Elsevier BV, Vol. 343 ( 2021-09), p. 130060-
    Type of Medium: Online Resource
    ISSN: 0925-4005
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 1500731-5
    detail.hit.zdb_id: 1021505-0
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  • 8
    In: Cancer Cell, Elsevier BV, Vol. 20, No. 6 ( 2011-12), p. 701-714
    Type of Medium: Online Resource
    ISSN: 1535-6108
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2011
    detail.hit.zdb_id: 2074034-7
    detail.hit.zdb_id: 2078448-X
    SSG: 12
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  • 9
    In: Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 53, No. 6 ( 2022-06), p. 1984-1992
    Abstract: The role of stroke etiology subtype in patients with acute large vessel occlusion on the occurrence of hemorrhagic transformation (HT) after endovascular treatment is poorly studied, and which factors mediate their relationship remains largely unknown. We utilized nationwide registry data to explore the association of stroke subtype (cardioembolism versus large artery atherosclerosis) with HT and to identify the possible mediators. Methods: A total of 1015 subjects were selected from the ANGEL-ACT registry (Endovascular Treatment Key Technique and Emergency Work Flow Improvement of Acute Ischemic Stroke)—a prospective consecutive cohort of acute large vessel occlusion patients undergoing endovascular treatment at 111 hospitals in China between November 2017 and March 2019—and divided into large artery atherosclerosis (n=538) and cardioembolism (n=477) according to the Trial of ORG 10172 in Acute Stroke Treatment criteria. The types of HT included any intracerebral hemorrhage (ICH), parenchymal hematoma, and symptomatic ICH within 24 hours after endovascular treatment. The association between stroke subtype and HT was analyzed using a logistic regression model. Mediation analysis was done to assess how much of the effect of stroke subtype on HT was mediated through the identified mediators. Results: Stroke subtype (cardioembolism versus large artery atherosclerosis) was associated with increased risk of any ICH (29.8% versus 16.5%; odds ratio, 2.03 [95% CI, 1.22–3.36]), parenchymal hematoma (14.3% versus 5.4%; odds ratio, 2.90 [95% CI, 1.38–6.13] ), and symptomatic ICH (9.9% versus 4.7%; odds ratio, 2.59 [95% CI, 1.09–6.16]) after adjustment for potential confounders. The more thrombectomy passes in cardioembolism patients had a significant mediation effect on the association of stroke subtype with increased risk of HT (any ICH, 15.9%; parenchymal hematoma, 13.4%; symptomatic ICH, 14.2%, respectively). Conclusions: Stroke subtype is an independent risk factor for HT within 24 hours following endovascular treatment among acute large vessel occlusion patients. Mediation analyses propose that stroke subtype contributes to HT partly through thrombectomy pass, suggesting a possible pathomechanistic link. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03370939.
    Type of Medium: Online Resource
    ISSN: 0039-2499 , 1524-4628
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 1467823-8
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  • 10
    In: Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 52, No. 4 ( 2021-04), p. 1203-1212
    Abstract: The benefit of endovascular treatment (EVT) for large vessel occlusion in clinical practice in developing countries like China needs to be confirmed. The aim of the study was to determine whether the benefit of EVT for acute ischemic stroke in randomized trials could be generalized to clinical practice in Chinese population. Methods: We conducted a prospective registry of EVT at 111 centers in China. Patients with acute ischemic stroke caused by imaging-confirmed intracranial large vessel occlusion and receiving EVT were included. The primary outcome was functional independence at 90 days defined as a modified Rankin Scale score of 0 to 2. Outcomes of specific subgroups in the anterior circulation were reported and logistic regression was performed to predict the primary outcome. Results: Among the 1793 enrolled patients, 1396 (77.9%) had anterior circulation large vessel occlusion (median age, 66 [56–73] years) and 397 (22.1%) had posterior circulation large vessel occlusion (median age, 64 [55–72] years). Functional independence at 90 days was reached in 45% and 44% in anterior and posterior circulation groups, respectively. For anterior circulation population, underlying intracranial atherosclerotic disease was identified in 29% of patients, with higher functional independence at 90 days (52% versus 44%; P =0.0122) than patients without intracranial atherosclerotic disease. In the anterior circulation population, after adjusting for baseline characteristics, procedure details, and early outcomes, the independent predictors for functional independence at 90 days were age 〈 66 years (odds ratio [OR], 1.733 [95% CI, 1.213–2.476] ), time from onset to puncture 〉 6 hours (OR, 1.536 [95% CI, 1.065–2.216]), local anesthesia (OR, 2.194 [95% CI, 1.325–3.633] ), final modified Thrombolysis in Cerebral Infarction 2b/3 (OR, 2.052 [95% CI, 1.085–3.878]), puncture-to-reperfusion time ≤1.5 hours (OR, 1.628 [95% CI, 1.098–2.413] ), and National Institutes of Health Stroke Scale score 24 hours after the procedure 〈 11 (OR, 9.126 [95% CI, 6.222–13.385]). Conclusions: Despite distinct characteristics in the Chinese population, favorable outcome of EVT can be achieved in clinical practice in China. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03370939.
    Type of Medium: Online Resource
    ISSN: 0039-2499 , 1524-4628
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 1467823-8
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