In:
Cardiology Research and Practice, Hindawi Limited, Vol. 2019 ( 2019-04-01), p. 1-10
Abstract:
Background . The relationship between heart rate in CAD patients who underwent percutaneous coronary intervention (PCI) and had long-term outcomes over up to 10 years of follow-up has not been investigated. Methods . All patients were from the CORFCHD-PCI, a retrospective cohort study that included a total of 6050 CAD patients who underwent PCI from January 2008 to December 2016. One patient was excluded due to a lack of heart rate data. Ultimately, 6049 patients were enrolled. The primary outcome was long-term mortality after PCI. Results . Patients were divided into 5 groups according to heart rate quintiles: 1st quintile (heart rate 〈 66 beats/min; n = 1123 ), 2nd quintile (heart rate ≥66 beats/min to 72 beats/min; n = 1010 ), 3rd quintile (heart rate ≥72 beats/min to 78 beats/min; n = 1442 ), 4th quintile (heart rate ≥78 beats/min to 84 beats/min; n = 1211 ), and 5th quintile (heart rate ≥84 beats/min; n = 1263 ). After multivariate Cox regression analyses, the respective risks of ACM, CM, and MACEs were increased 79.1% (hazard risk (HR) = 1.791, 95% CI: 1.207–2.657, P = 0.004 ), 56.9% (HR = 1.569, 95% CI: 1.019–2.416, P = 0.041 ), and 25.5% (HR = 1.255, 95% CI: 0.990–1.590, P = 0.060 ) in the 4th quintile and 98.7% (HR = 1.987, 95% CI: 1.344–2.937, P = 0.001 ), 98.8% (HR = 1.988, 95% CI: 1.310–3.016, P 〈 0.001 ), and 0.36.1% (HR = 1.361, 95% CI: 1.071–1.730, P = 0.012 ) in the 5th quintile compared with those in the 1st quintile. Patients with a heart rate of ≥80 beats/min had 89.4%, 115.2%, and 39.1% increased risk of ACM, CM, and MACEs, respectively, compared to those patients with a heart rate of 〈 80 beats/min. Conclusion . The present study indicated that the resting heart rate is an independent predictor of adverse long-term outcomes in CAD patients who underwent PCI.
Type of Medium:
Online Resource
ISSN:
2090-8016
,
2090-0597
DOI:
10.1155/2019/5432076
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2019
detail.hit.zdb_id:
2506187-2
Bookmarklink