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  • 1
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 10, No. 5 ( 2020-01-28), p. 101-104
    Abstract: In the article presents data on the management of a 48-year-old patient with HIV infection, urogenital infection with pregnancy, which occurred as a result of IVF, with premature effusion of amniotic fluid at 23 weeks of pregnancy with the syndrome of growth retardation of 2 fetus in monochoric diamniotic twins. After the discharge of the amniotic fluid, the patient was treated for six days in an infectious hospital, then transferred to the perinatal center, where blood tests noted moderatemanifestations of endotoxicosis, increased levels of aminotransferases and an inflammatory reaction of the body. The course of treatment included detoxification methods (plasmapheresis, hemosorption, photomodification of blood with ultraviolet, laser rays), which contributed to the normalization of blood tests, prolongation of pregnancy for another three weeks in the absence of septic complications after operative childbirth in the mother and in newborn girls. At birth, 1 childs weight, body length and Apgar score were 750 g., 29 sm. and3/5points, respectively, in 2 children 590 g., 30 sm. and1/3points, respectively. The children required treatment from resuscitators, at the second stage of nursing, from rehabilitation specialists.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2020
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  • 2
    Online Resource
    Online Resource
    ECO-Vector LLC ; 2017
    In:  Pediatrician (St. Petersburg) Vol. 8, No. 6 ( 2017-12-28), p. 86-93
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 8, No. 6 ( 2017-12-28), p. 86-93
    Abstract: Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of neonatal mortality and development of severe neurological disorders that determine the quality of life of these children. In developed countries, the frequency of detection of hypoxic-ischemic encephalopathy (HIE) among full-term newborns is 1-6 per 1.000 live births. In our country, hypoxic-ischemic brain damage is observed in 15-30% of full-term newborns. The term HIE is a clinical diagnosis combining neurological disorders and biochemical changes caused by perinatal HI (hypoxiа-ischemia). The pattern of acute brain damage depends on the degree of cerebral maturity, the severity and duration of hypoxiа-ischemia. The most vulnerable regions are the structures of the brain with high level of metabolism. Such structures in term infants include cortical neurons and neurons of basal nuclei, a subcortical white matter. MRI allows to diagnose brain lesions in term infants in the acute period of HIE. Safety, non-invasiveness and large diagnostic capabilities of MRI allow this method to be considered the gold standard of neuroimaging in neonatology. In this review we described the main MRI patterns of brain injury in term neonates following HIE.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2017
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  • 3
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 10, No. 1 ( 2019-12-15), p. 29-36
    Abstract: The aim of the study was to determine the capabilities of magnetic resonance morphometry and diffusion tensor imaging in the diagnosis of bilateral spastic forms of cerebral palsy in children. The main groups were 33 children aged from 1 year to 4 years 5 months. with bilateral spastic forms of cerebral palsy, the comparison group – 11 children who did not have movement disorders. The patients underwent magnetic resonance morphometry, diffusion tensor imaging. A comparison was made between the volumes of brain structures and diffusion values between groups. Significant differences (p 〈 0,05) were found in the volumes of the right lateral, 3rd ventricles, white matter, thalamuses, globus pallidus, putamen, hippocampus. Significant differences (p 〈 0,05) in diffusion values in the thalamuses and in the posterior limb of internal capsules were also identified. The correlation of the identified changes with the clinic of the disease was demonstrated. The obtained data demonstrate wide possibilities and high diagnostic value in the detection of bilateral spastic forms of cerebral palsy in children.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2019
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  • 4
    Online Resource
    Online Resource
    ECO-Vector LLC ; 2020
    In:  Pediatrician (St. Petersburg) Vol. 10, No. 6 ( 2020-03-04), p. 93-99
    In: Pediatrician (St. Petersburg), ECO-Vector LLC, Vol. 10, No. 6 ( 2020-03-04), p. 93-99
    Abstract: Subdural hematoma is a sufficiently rare, but serious pathology of the brain in infants, which can lead to severe neurological deficit or result in death. Subdural hematomas are detected in 2025 per 100,000 children under 1 year. A retrospective analysis of autopsy material revealed that subdural hematomas were diagnosed in 72% of children who died before the age of 5 months from intracranial hemorrhage. According to localization, subdural hematomas are divided into supra- and subtentorial, mainly associated localization, which are located along the tent of cerebellum and sickle of the brain, mainly. The main mechanism of development of subdural hematomas is associated with the rupture of the bridge veins of the subdural space as a result of their tension, both traumatic etiology and nontraumatic brain damage, accompanied by progressive cerebral atrophy. It is believed that perinatal hypoxic-ischemic brain damage is one of the leading etiological factors of developed subdural hematomas in young children. In addition, the formation of subdural hematomas in young children can be observed with intraamniotic infections, congenital fermentopathies, and above all, in children with aciduria. In some infants, subdural hematomas occur without clinical manifestation, but in most cases are accompanied by the development of neurological disorders, both in acute and in distant periods. In the main, subdural hematomas in the acute period manifest with focal convulsions with secondary generalization of seizures, behavioral disturbances, respiration, and symptoms of intracranial hypertension. During the formation of chronic subdural hematoma, development of structural epilepsy (up to 20%), microcephaly, impaired psychomotor development is observed. In 55% of young children with acute subdural hematomas, the formation of chronic subdural hematomas is observed.
    Type of Medium: Online Resource
    ISSN: 2587-6252 , 2079-7850
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2020
    Library Location Call Number Volume/Issue/Year Availability
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