In:
Pure and Applied Chemistry, Walter de Gruyter GmbH, Vol. 79, No. 4 ( 2007-01-01), p. 685-700
Abstract:
The novel polyketide (+)-discodermolide was isolated in very small quantities from sponge extracts. This compound is one of several microtubule stabilizers showing promise as novel chemotherapeutic agents for the treatment of cancer. The clinical evaluation of this and similar compounds is hampered by lack of material, and at present, the only way to obtain the necessary quantities is total chemical synthesis.
Type of Medium:
Online Resource
ISSN:
1365-3075
,
0033-4545
DOI:
10.1351/pac200779040685
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2007
detail.hit.zdb_id:
2022101-0
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