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Self-study of the non-extension sign in an e-learning program improves diagnostic accuracy of invasion depth of early gastric cancer

Kato, Minoru ; Uedo, Noriya ; Nagahama, Takashi ; [et al.]

Georg Thieme Verlag KG ; 2019

In: Endoscopy International Open Vol. 07, No. 07 ( 2019-07), p. E871-E882

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In: Endoscopy International Open, Georg Thieme Verlag KG, Vol. 07, No. 07 ( 2019-07), p. E871-E882

Abstract: Background and study aims We developed an e-learning program for endoscopic diagnosis of invasion depth of early gastric cancer (EGC) using a simple diagnostic criterion called non-extension sign, and the contribution of self-study quizzes to improvement of diagnostic accuracy was evaluated. Methods We conducted a prospective randomized controlled study that recruited endoscopists throughout Japan. After completing a pretest, the participants watched video lectures and undertook post-test 1. The participants were then randomly allocated to either the self-study or non-self-study group, and participants in the first group completed the self-study program that comprised 100-case quizzes. Finally, participants in both groups undertook post-test 2. The primary endpoint was the difference in post-test 2 scores between the groups. The perfect score for the tests was set as 100 points. Results A total of 423 endoscopists completed the pretest and were enrolled. Post-test 1 was completed by 415 endoscopists and 208 were allocated to the self-study group and 207 to the non-self-study group. Two hundred and four in the self-study group and 205 in the non-self-study group were included in the analysis. Video lectures improved the mean score of post-test 1 from 72 to 77 points. Participants who completed the self-study quizzes showed significantly better post-test 2 scores compared with the non-self-study group (80 vs. 76 points, respectively, P 〈 0.0001). Conclusions Our e-learning program showed that self-study quizzes consolidated knowledge of the non-extension sign and improved diagnostic ability of endoscopists for invasion depth of EGC.

Type of Medium: Online Resource

ISSN: 2364-3722 , 2196-9736

URL: Article

DOI: 10.1055/a-0902-4467

Language: English

Publisher: Georg Thieme Verlag KG

Publication Date: 2019

detail.hit.zdb_id: 2761052-4

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CKD, Brain Atrophy, and White Matter Lesion Volume: The Japan Prospective Studies Collaboration for Aging and Dementia

Maki, Kenji ; Ohara, Tomoyuki ; Hata, Jun ; [et al.]

Elsevier BV ; 2023

In: Kidney Medicine Vol. 5, No. 3 ( 2023-03), p. 100593-

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In: Kidney Medicine, Elsevier BV, Vol. 5, No. 3 ( 2023-03), p. 100593-

Type of Medium: Online Resource

ISSN: 2590-0595

URL: Article

DOI: 10.1016/j.xkme.2022.100593

Language: English

Publisher: Elsevier BV

Publication Date: 2023

detail.hit.zdb_id: 3009701-0

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5th Japanese Association of Hepato-Biliary-Pancreatic Surgery : October 14?15, 1993, Arcadia Ichigaya, Tokyo, Japan President: Fujio Hanyu

Miyazaki, Kohji ; Tsutsumi, Nobuo ; Kitahara, Kenji ; [et al.]

Springer Science and Business Media LLC ; 1993

In: Journal of Hepato-Biliary-Pancreatic Surgery Vol. 1, No. 1 ( 1993-2), p. 42-104

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In: Journal of Hepato-Biliary-Pancreatic Surgery, Springer Science and Business Media LLC, Vol. 1, No. 1 ( 1993-2), p. 42-104

Type of Medium: Online Resource

ISSN: 0944-1166 , 1436-0691

URL: Article

DOI: 10.1007/BF01235934

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 1993

detail.hit.zdb_id: 2536390-6

detail.hit.zdb_id: 1473162-9

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Clinical and histological features in pediatric and adolescent/young adult patients with renal disease: a cross-sectional analysis of the Japan Renal Biopsy Registry (J-RBR)

Urushihara, Maki ; Sato, Hiroshi ; Shimizu, Akira ; [et al.]

Springer Science and Business Media LLC ; 2021

In: Clinical and Experimental Nephrology Vol. 25, No. 9 ( 2021-09), p. 1018-1026

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In: Clinical and Experimental Nephrology, Springer Science and Business Media LLC, Vol. 25, No. 9 ( 2021-09), p. 1018-1026

Type of Medium: Online Resource

ISSN: 1342-1751 , 1437-7799

URL: Article

DOI: 10.1007/s10157-021-02077-w

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2021

detail.hit.zdb_id: 1499111-1

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Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force

Lee, Ho ; Chubachi, Shotaro ; Namkoong, Ho ; [et al.]

Springer Science and Business Media LLC ; 2022

In: BMC Infectious Diseases Vol. 22, No. 1 ( 2022-12-12)

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In: BMC Infectious Diseases, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12-12)

Abstract: We aimed to elucidate differences in the characteristics of patients with coronavirus disease 2019 (COVID-19) requiring hospitalization in Japan, by COVID-19 waves, from conventional strains to the Delta variant. Methods We used secondary data from a database and performed a retrospective cohort study that included 3261 patients aged ≥ 18 years enrolled from 78 hospitals that participated in the Japan COVID-19 Task Force between February 2020 and September 2021. Results Patients hospitalized during the second (mean age, 53.2 years [standard deviation {SD}, ± 18.9]) and fifth (mean age, 50.7 years [SD ± 13.9] ) COVID-19 waves had a lower mean age than those hospitalized during the other COVID-19 waves. Patients hospitalized during the first COVID-19 wave had a longer hospital stay (mean, 30.3 days [SD ± 21.5], p 〈 0.0001), and post-hospitalization complications, such as bacterial infections (21.3%, p 〈 0.0001), were also noticeable. In addition, there was an increase in the use of drugs such as remdesivir/baricitinib/tocilizumab/steroids during the latter COVID-19 waves. In the fifth COVID-19 wave, patients exhibited a greater number of presenting symptoms, and a higher percentage of patients required oxygen therapy at the time of admission. However, the percentage of patients requiring invasive mechanical ventilation was the highest in the first COVID-19 wave and the mortality rate was the highest in the third COVID-19 wave. Conclusions We identified differences in clinical characteristics of hospitalized patients with COVID-19 in each COVID-19 wave up to the fifth COVID-19 wave in Japan. The fifth COVID-19 wave was associated with greater disease severity on admission, the third COVID-19 wave had the highest mortality rate, and the first COVID-19 wave had the highest percentage of patients requiring mechanical ventilation.

Type of Medium: Online Resource

ISSN: 1471-2334

URL: Article

DOI: 10.1186/s12879-022-07927-w

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2022

detail.hit.zdb_id: 2041550-3

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Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study

Matsubara, Yuta ; Kiyohara, Hiroki ; Mikami, Yohei ; [et al.]

Springer Science and Business Media LLC ; 2024

In: Journal of Gastroenterology

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In: Journal of Gastroenterology, Springer Science and Business Media LLC

Type of Medium: Online Resource

ISSN: 0944-1174 , 1435-5922

URL: Article

DOI: 10.1007/s00535-023-02071-x

Language: English

Publisher: Springer Science and Business Media LLC

Publication Date: 2024

detail.hit.zdb_id: 1473159-9

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Signet-ring Cell Carcinoma in Hyperplastic Polyp of the Stomach

Yoshida, Kenta ; Mikami, Tatsuya ; Oyama, Takao ; [et al.]

Japanese Society of Internal Medicine ; 2019

In: Internal Medicine Vol. 58, No. 24 ( 2019-12-15), p. 3531-3535

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In: Internal Medicine, Japanese Society of Internal Medicine, Vol. 58, No. 24 ( 2019-12-15), p. 3531-3535

Type of Medium: Online Resource

ISSN: 0918-2918 , 1349-7235

URL: Article

DOI: 10.2169/internalmedicine.2860-19

RVK:

XA 49642

Language: English

Publisher: Japanese Society of Internal Medicine

Publication Date: 2019

detail.hit.zdb_id: 2202453-0

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Evaluation of metabolic dysfunction-associated fatty liver disease using FibroScan, diet, and microbiota: A large cross-sectional study

Tateda, Tetsuyuki ; Iino, Chikara ; Sasada, Takafumi ; [et al.]

Public Library of Science (PLoS) ; 2022

In: PLOS ONE Vol. 17, No. 11 ( 2022-11-23), p. e0277930-

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In: PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 11 ( 2022-11-23), p. e0277930-

Abstract: We evaluated the clinical characteristics of metabolic dysfunction-associated fatty liver disease (MAFLD) to evaluate the usefulness of the MAFLD diagnostic criteria in a resident health survey. Methods In 1056 participants of a health survey, we compared obesity, diabetes, metabolic dysregulation, FibroScan-aspartate aminotransferase (FAST) score, dietary habits, and gut microbiota between healthy individuals and participants with MAFLD and Nonalcoholic fatty liver disease (NAFLD). Results The proportion of participants with MAFLD in the fatty liver was higher than that with NAFLD (88.1% vs. 75.5%, respectively). Of 36 participants with a FAST score 〉 0.35, 29 (80.6%) participants had MAFLD and 23 (63.9%) participants had NAFLD. Of 29 patients with liver fibrosis, 26 (89.7%) participants had obesity and metabolic dysregulation. In the evaluation of diet, the total energy, protein, dietary fiber, and salt intake were significantly higher in participants with MAFLD than those in participants without fatty liver. In the microbiota analysis, the results of the linear discriminant analysis effect size analysis revealed nine bacterial genera that were significantly different in participants with MAFLD in comparison with participants without fatty liver. Of these genera, the relative abundance of Blautia was especially low in participants with MAFLD. Conclusion In a resident health survey, participants with MAFLD had a higher proportion of fatty liver than those with NAFLD. MAFLD criteria could help in improved screening of participants with liver fibrosis. Therefore, the MAFLD criteria could be a useful diagnostic tool for aggressively identifying participants with a high risk of fatty liver. Additionally, Blautia might be involved in the development of MAFLD.

Type of Medium: Online Resource

ISSN: 1932-6203

URL: Article

DOI: 10.1371/journal.pone.0277930

DOI: 10.1371/journal.pone.0277930.g001

DOI: 10.1371/journal.pone.0277930.g002

DOI: 10.1371/journal.pone.0277930.g003

DOI: 10.1371/journal.pone.0277930.g004

DOI: 10.1371/journal.pone.0277930.t001

DOI: 10.1371/journal.pone.0277930.t002

DOI: 10.1371/journal.pone.0277930.t003

DOI: 10.1371/journal.pone.0277930.t004

DOI: 10.1371/journal.pone.0277930.t005

DOI: 10.1371/journal.pone.0277930.t006

DOI: 10.1371/journal.pone.0277930.t007

DOI: 10.1371/journal.pone.0277930.t008

DOI: 10.1371/journal.pone.0277930.s001

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2022

detail.hit.zdb_id: 2267670-3

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Association of serum creatinine-to-cystatin C ratio with skeletal muscle mass and strength in nonalcoholic fatty liver disease in the Iwaki Health Promotion Project

Mikami, Kenichiro ; Endo, Tetsu ; Sawada, Naoya ; [et al.]

The Society for Free Radical Research Japan ; 2022

In: Journal of Clinical Biochemistry and Nutrition Vol. 70, No. 3 ( 2022), p. 273-282

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In: Journal of Clinical Biochemistry and Nutrition, The Society for Free Radical Research Japan, Vol. 70, No. 3 ( 2022), p. 273-282

Type of Medium: Online Resource

ISSN: 0912-0009 , 1880-5086

URL: Article

DOI: 10.3164/jcbn.21-61

Language: English

Publisher: The Society for Free Radical Research Japan

Publication Date: 2022

detail.hit.zdb_id: 2217563-5

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〈i〉Erratum for〈/i〉 Signet-ring Cell Carcinoma in Hyperplastic Polyp of the Stomach

Yoshida, Kenta ; Mikami, Tatsuya ; Oyama, Takao ; [et al.]

Japanese Society of Internal Medicine ; 2020

In: Internal Medicine Vol. 59, No. 9 ( 2020-5-1), p. 1237-1237

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In: Internal Medicine, Japanese Society of Internal Medicine, Vol. 59, No. 9 ( 2020-5-1), p. 1237-1237

Type of Medium: Online Resource

ISSN: 0918-2918 , 1349-7235

URL: Article

DOI: 10.2169/internalmedicine.E001-20

RVK:

XA 49642

Language: English

Publisher: Japanese Society of Internal Medicine

Publication Date: 2020

detail.hit.zdb_id: 2202453-0

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